Puma Biotechnology, Inc. (PBYI)
USD 2.89
(2.12%)
USD 2.89
(2.12%)
| Year | Operating Income | Operating Income Growth |
|---|---|---|
| 2023 | 32.64 Million USD | 40.36% |
| 2022 | 23.7 Million USD | 366.35% |
| 2021 | -8.89 Million USD | 70.73% |
| 2020 | -30.4 Million USD | 22.25% |
| 2019 | -39.1 Million USD | 58.71% |
| 2018 | -94.7 Million USD | 67.61% |
| 2017 | -292.4 Million USD | -5.71% |
| 2016 | -276.6 Million USD | -15.11% |
| 2015 | -240.3 Million USD | -68.87% |
| 2014 | -142.3 Million USD | -159.52% |
| 2013 | -54.83 Million USD | 26.3% |
| 2012 | -74.4 Million USD | -632.52% |
| 2011 | -10.15 Million USD | -63474.49% |
| 2010 | -15.97 Thousand USD | 5.11% |
| 2009 | -16.83 Thousand USD | -19.55% |
| 2008 | -14.08 Thousand USD | 99.91% |
| 2007 | -15.09 Million USD | 0.0% |
| Year | Operating Income | Operating Income Growth |
|---|---|---|
| 2024 Q1 | -2.29 Million USD | -115.54% |
| 2024 Q2 | -2.17 Million USD | 5.22% |
| 2023 Q3 | 8.58 Million USD | 75.49% |
| 2023 Q4 | 14.79 Million USD | 72.37% |
| 2023 FY | 33.26 Million USD | 40.36% |
| 2023 Q2 | 4.89 Million USD | 12.07% |
| 2023 Q1 | 4.36 Million USD | -56.35% |
| 2022 Q2 | 12.05 Million USD | 1862.87% |
| 2022 Q3 | 9.67 Million USD | -19.78% |
| 2022 Q4 | 10 Million USD | 3.38% |
| 2022 Q1 | -684 Thousand USD | -110.06% |
| 2022 FY | 23.7 Million USD | 366.35% |
| 2021 Q2 | -16.63 Million USD | -182.56% |
| 2021 FY | -8.89 Million USD | 70.73% |
| 2021 Q1 | 20.14 Million USD | 278.28% |
| 2021 Q4 | 6.8 Million USD | 175.94% |
| 2021 Q3 | -8.95 Million USD | 46.17% |
| 2020 Q1 | -16.93 Million USD | -94.63% |
| 2020 Q4 | -11.3 Million USD | 6.85% |
| 2020 FY | -30.4 Million USD | 22.25% |
| 2020 Q2 | 7.12 Million USD | 142.1% |
| 2020 Q3 | -12.13 Million USD | -270.16% |
| 2019 Q2 | -25.78 Million USD | -155.58% |
| 2019 Q4 | -8.7 Million USD | 39.58% |
| 2019 FY | -39.1 Million USD | 58.71% |
| 2019 Q1 | -10.08 Million USD | 45.77% |
| 2019 Q3 | -14.4 Million USD | 44.14% |
| 2018 Q3 | -11.3 Million USD | 72.73% |
| 2018 Q4 | -18.6 Million USD | -64.6% |
| 2018 Q2 | -41.44 Million USD | -77.16% |
| 2018 Q1 | -23.39 Million USD | 63.22% |
| 2018 FY | -94.7 Million USD | 67.61% |
| 2017 Q4 | -63.6 Million USD | 17.87% |
| 2017 Q3 | -77.44 Million USD | 0.95% |
| 2017 FY | -292.4 Million USD | -5.71% |
| 2017 Q2 | -78.18 Million USD | -6.8% |
| 2017 Q1 | -73.2 Million USD | -0.41% |
| 2016 Q1 | -71.24 Million USD | -14.73% |
| 2016 FY | -276.6 Million USD | -15.11% |
| 2016 Q2 | -66.48 Million USD | 6.69% |
| 2016 Q3 | -65.99 Million USD | 0.73% |
| 2016 Q4 | -72.9 Million USD | -10.46% |
| 2015 Q1 | -52.59 Million USD | -10.5% |
| 2015 FY | -240.3 Million USD | -68.87% |
| 2015 Q4 | -62.1 Million USD | -2.25% |
| 2015 Q3 | -60.73 Million USD | 6.44% |
| 2015 Q2 | -64.91 Million USD | -23.41% |
| 2014 Q4 | -47.6 Million USD | -32.37% |
| 2014 Q3 | -35.95 Million USD | 7.57% |
| 2014 FY | -142.3 Million USD | -159.52% |
| 2014 Q1 | -19.81 Million USD | -23.95% |
| 2014 Q2 | -38.9 Million USD | -96.3% |
| 2013 Q4 | -15.98 Million USD | -11.57% |
| 2013 FY | -54.83 Million USD | 26.3% |
| 2013 Q1 | -11.8 Million USD | 46.36% |
| 2013 Q2 | -12.7 Million USD | -7.69% |
| 2013 Q3 | -14.33 Million USD | -12.78% |
| 2012 Q1 | -11.85 Million USD | -16.86% |
| 2012 Q4 | -22 Million USD | 14.97% |
| 2012 Q3 | -25.87 Million USD | -75.09% |
| 2012 Q2 | -14.77 Million USD | -24.68% |
| 2012 FY | -74.4 Million USD | -632.52% |
| 2011 Q3 | -4962.00 USD | -49.82% |
| 2011 Q1 | -6883.00 USD | -22.08% |
| 2011 Q2 | -3312.00 USD | 51.88% |
| 2011 Q4 | -10.14 Million USD | -204283.39% |
| 2011 FY | -10.15 Million USD | -63474.49% |
| 2010 Q4 | -5638.00 USD | -76.02% |
| 2010 Q1 | -4697.00 USD | -41.82% |
| 2010 Q2 | -2438.00 USD | 48.09% |
| 2010 Q3 | -3203.00 USD | -31.38% |
| 2010 FY | -15.97 Thousand USD | 5.11% |
| 2009 Q2 | -4209.00 USD | 29.93% |
| 2009 FY | -16.83 Thousand USD | -19.55% |
| 2009 Q1 | -6007.00 USD | -167.1% |
| 2009 Q3 | -3308.00 USD | 21.41% |
| 2009 Q4 | -3312.00 USD | -0.12% |
| 2008 Q4 | -2249.00 USD | 43.32% |
| 2008 FY | -14.08 Thousand USD | 99.91% |
| 2008 Q1 | -4491.00 USD | 99.97% |
| 2008 Q2 | -3375.00 USD | 24.85% |
| 2008 Q3 | -3968.00 USD | -17.57% |
| 2007 FY | -15.09 Million USD | 0.0% |
| 2007 Q3 | - USD | 0.0% |
| 2007 Q4 | -15.09 Million USD | 0.0% |
| Name | Operating Income | Operating Income Difference |
|---|---|---|
| Akebia Therapeutics, Inc. | -46.25 Million USD | 170.564% |
| Jaguar Health, Inc. | -34.29 Million USD | 195.185% |
| Keros Therapeutics, Inc. | -169.94 Million USD | 119.207% |
| Longboard Pharmaceuticals, Inc. | -56.75 Million USD | 157.506% |
| Alnylam Pharmaceuticals, Inc. | -282.17 Million USD | 111.567% |
| Ligand Pharmaceuticals Incorporated | 11.94 Million USD | -173.321% |
| ContextLogic Inc. | -328 Million USD | 109.951% |
| MiMedx Group, Inc. | 37.11 Million USD | 12.059% |
| MEI Pharma, Inc. | 14.54 Million USD | -124.453% |
| AlloVir, Inc. | -181.33 Million USD | 118.0% |
| Novavax, Inc. | -566.51 Million USD | 105.762% |
| Aptorum Group Limited | -10.52 Million USD | 410.168% |
| Ardelyx, Inc. | -63.27 Million USD | 151.584% |
| Arrowhead Pharmaceuticals, Inc. | -205 Million USD | 115.922% |
| Psyence Biomedical Ltd. | -2.75 Million USD | 1286.122% |
| Vaxcyte, Inc. | -468.04 Million USD | 106.974% |
| Precigen, Inc. | -88.92 Million USD | 136.706% |
| Pharming Group N.V. | -4.87 Million USD | 768.915% |
| Phathom Pharmaceuticals, Inc. | -167.31 Million USD | 119.508% |
| Pieris Pharmaceuticals, Inc. | -29.75 Million USD | 209.692% |
| Rigel Pharmaceuticals, Inc. | -20.49 Million USD | 259.289% |
| Avidity Biosciences, Inc. | -235.59 Million USD | 113.854% |
| TransCode Therapeutics, Inc. | -19.41 Million USD | 268.087% |
| Reviva Pharmaceuticals Holdings, Inc. | -24.3 Million USD | 234.284% |
| Reviva Pharmaceuticals Holdings, Inc. | -24.3 Million USD | 234.284% |
| Bicycle Therapeutics plc | -189.94 Million USD | 117.184% |
| Sangamo Therapeutics, Inc. | -274 Million USD | 111.912% |
| Sol-Gel Technologies Ltd. | -29.3 Million USD | 211.38% |
| Acelyrin, Inc. | -422.06 Million USD | 107.733% |
| SELLAS Life Sciences Group, Inc. | -37.86 Million USD | 186.192% |
| Sensei Biotherapeutics, Inc. | -37.06 Million USD | 188.064% |
| Senti Biosciences, Inc. | -92.72 Million USD | 135.2% |
| Stoke Therapeutics, Inc. | -114.77 Million USD | 128.439% |
| AbCellera Biologics Inc. | -237.2 Million USD | 113.76% |
| Alaunos Therapeutics, Inc. | -34.26 Million USD | 195.252% |
| BioXcel Therapeutics, Inc. | -171.78 Million USD | 119.001% |
| Entrada Therapeutics, Inc. | -3.16 Million USD | 1132.258% |
| Chimerix, Inc. | -93.06 Million USD | 135.072% |
| VistaGen Therapeutics, Inc. | -33.02 Million USD | 198.846% |
| Windtree Therapeutics, Inc. | -17.53 Million USD | 286.1% |
| Corbus Pharmaceuticals Holdings, Inc. | -45.07 Million USD | 172.409% |
| Viracta Therapeutics, Inc. | -50.69 Million USD | 164.388% |
| Elevation Oncology, Inc. | -45.44 Million USD | 171.823% |
| Alkermes plc | 414.12 Million USD | 92.118% |
| Fortress Biotech, Inc. | -142.34 Million USD | 122.931% |
| Fortress Biotech, Inc. | -142.34 Million USD | 122.931% |
| Agenus Inc. | -159.54 Million USD | 120.458% |
| HOOKIPA Pharma Inc. | -97.69 Million USD | 133.41% |
| Dyadic International, Inc. | -8.22 Million USD | 496.61% |
| ImmuCell Corporation | -5.74 Million USD | 667.842% |
| Eton Pharmaceuticals, Inc. | -1.19 Million USD | 2838.255% |
| IDEAYA Biosciences, Inc. | -134.42 Million USD | 124.28% |
| Lantern Pharma Inc. | -17.87 Million USD | 282.575% |
| Immix Biopharma, Inc. | -16.14 Million USD | 302.217% |
| Incyte Corporation | 620.52 Million USD | 94.74% |
| IO Biotech, Inc. | -91.44 Million USD | 135.694% |
| Janux Therapeutics, Inc. | -72.97 Million USD | 144.725% |
| Inhibikase Therapeutics, Inc. | -20.08 Million USD | 262.471% |
| Outlook Therapeutics, Inc. | -53.12 Million USD | 161.438% |
| Syros Pharmaceuticals, Inc. | -128.98 Million USD | 125.305% |
| Kintara Therapeutics, Inc. | -8.5 Million USD | 483.955% |
| Barinthus Biotherapeutics plc | -83.91 Million USD | 138.897% |
| Madrigal Pharmaceuticals, Inc. | -380.49 Million USD | 108.578% |
| Sorrento Therapeutics, Inc. | -504.31 Million USD | 106.472% |
| NextCure, Inc. | -67.63 Million USD | 148.258% |
| Ocuphire Pharma, Inc. | -10.56 Million USD | 409.003% |
| Onconetix, Inc. | -36.03 Million USD | 190.58% |
| Oncternal Therapeutics, Inc. | -41.71 Million USD | 178.247% |
| Opthea Limited | -191.84 Million USD | 117.014% |
| PDS Biotechnology Corporation | -43.04 Million USD | 175.827% |
| PureTech Health plc | -146.19 Million USD | 122.326% |
| Pyxis Oncology, Inc. | -82.19 Million USD | 139.71% |
| Seer, Inc. | -103.46 Million USD | 131.548% |
| Salarius Pharmaceuticals, Inc. | -12.89 Thousand USD | 253222.543% |
| Clearside Biomedical, Inc. | -24.84 Million USD | 231.38% |
| Telomir Pharmaceuticals, Inc. Common Stock | -3.94 Million USD | 927.996% |
| VYNE Therapeutics Inc. | -29.25 Million USD | 211.559% |
| Wave Life Sciences Ltd. | -67.99 Million USD | 148.003% |
| Xeris Biopharma Holdings, Inc. | -44.01 Million USD | 174.165% |
| C4 Therapeutics, Inc. | -139.03 Million USD | 123.477% |
| ChromaDex Corporation | -5.59 Million USD | 682.961% |
| TRACON Pharmaceuticals, Inc. | -6.89 Million USD | 573.181% |
| Caribou Biosciences, Inc. | -116.05 Million USD | 128.124% |
| CRISPR Therapeutics AG | -222.53 Million USD | 114.667% |
| Precision BioSciences, Inc. | -43.73 Million USD | 174.63% |
| Fate Therapeutics, Inc. | -190.51 Million USD | 117.133% |
| Innoviva, Inc. | 176.7 Million USD | 81.529% |
| Summit Therapeutics Inc. | -89.73 Million USD | 136.373% |
| Verrica Pharmaceuticals Inc. | -65.75 Million USD | 149.636% |
| Aadi Bioscience, Inc. | -71.93 Million USD | 145.376% |
| ESSA Pharma Inc. | -32.13 Million USD | 201.574% |
| GlycoMimetics, Inc. | -39.27 Million USD | 183.106% |
| GT Biopharma, Inc. | -13.57 Million USD | 340.424% |
| Inhibrx Biosciences, Inc. | -219.22 Million USD | 114.889% |
| Catalyst Pharmaceuticals, Inc. | 86.81 Million USD | 62.402% |
| Orchestra BioMed Holdings, Inc. | -51.5 Million USD | 163.371% |
| Alzamend Neuro, Inc. | -9.93 Million USD | 428.448% |
| Rocket Pharmaceuticals, Inc. | -259.65 Million USD | 112.57% |
| Aptose Biosciences Inc. | -52.35 Million USD | 162.342% |
| ZyVersa Therapeutics, Inc. | -14.42 Million USD | 326.34% |
| Soligenix, Inc. | -7.69 Million USD | 524.01% |
| Century Therapeutics, Inc. | -146.54 Million USD | 122.273% |
| Kura Oncology, Inc. | -165.8 Million USD | 119.686% |
| TScan Therapeutics, Inc. | -93.45 Million USD | 134.925% |
| Intensity Therapeutics, Inc. | -8.31 Million USD | 492.355% |
| Ocean Biomedical, Inc. | -2.48 Million USD | 1415.26% |
| CytomX Therapeutics, Inc. | -6.48 Million USD | 603.393% |
| Autolus Therapeutics plc | -195.02 Million USD | 116.736% |
| Mineralys Therapeutics, Inc. | -84.65 Million USD | 138.556% |
| EyePoint Pharmaceuticals, Inc. | -73.66 Million USD | 144.31% |
| Eterna Therapeutics Inc. | -21.13 Million USD | 254.436% |
| Adaptive Biotechnologies Corporation | -227.03 Million USD | 114.377% |
| GRI Bio, Inc. | -11.38 Million USD | 386.643% |
| Xenetic Biosciences, Inc. | -4.51 Million USD | 822.809% |
| Tenaya Therapeutics, Inc. | -131.19 Million USD | 124.879% |
| IGM Biosciences, Inc. | -263.46 Million USD | 112.389% |
| INmune Bio, Inc. | -29.74 Million USD | 209.747% |
| Heron Therapeutics, Inc. | -110.61 Million USD | 129.508% |
| SAB Biotherapeutics, Inc. | -38.07 Million USD | 185.725% |
| Pasithea Therapeutics Corp. | -15.97 Million USD | 304.263% |
| Entero Therapeutics, Inc. | -15.77 Million USD | 306.964% |
| Milestone Pharmaceuticals Inc. | -61.09 Million USD | 153.422% |
| X4 Pharmaceuticals, Inc. | -107.52 Million USD | 130.357% |
| Atara Biotherapeutics, Inc. | -276 Million USD | 111.826% |
| Coherus BioSciences, Inc. | -203.19 Million USD | 116.063% |
| Verastem, Inc. | -92.08 Million USD | 135.446% |
| Abeona Therapeutics Inc. | -47.13 Million USD | 169.248% |
| Pliant Therapeutics, Inc. | -184.14 Million USD | 117.725% |
| Tonix Pharmaceuticals Holding Corp. | -118.38 Million USD | 127.572% |
| Histogen Inc. | -10.64 Million USD | 406.68% |
| Aprea Therapeutics, Inc. | -15.47 Million USD | 310.962% |
| Surrozen, Inc. | -45.78 Million USD | 171.298% |
| Organovo Holdings, Inc. | -15.08 Million USD | 316.36% |
| Lixte Biotechnology Holdings, Inc. | -5.09 Million USD | 741.228% |
| Ovid Therapeutics Inc. | -59.28 Million USD | 155.059% |
| Panbela Therapeutics, Inc. | -51.29 Million USD | 163.633% |
| CASI Pharmaceuticals, Inc. | -25.28 Million USD | 229.114% |
| Cadrenal Therapeutics, Inc. Common Stock | -7.63 Million USD | 527.626% |
| Centessa Pharmaceuticals plc | -171.28 Million USD | 119.056% |
| Hepion Pharmaceuticals, Inc. | -48.44 Million USD | 167.371% |
| Arcturus Therapeutics Holdings Inc. | -78.2 Million USD | 141.736% |
| BioRestorative Therapies, Inc. | -15.22 Million USD | 314.444% |
| Apollomics, Inc. | -54.83 Million USD | 159.525% |
| Amarin Corporation plc | -67.58 Million USD | 148.293% |
| Mesoblast Limited | -58.79 Million USD | 155.516% |
| Turnstone Biologics Corp. | -59.03 Million USD | 155.292% |
| Kymera Therapeutics, Inc. | -165.53 Million USD | 119.718% |
| Synaptogenix, Inc. | -8.31 Million USD | 492.598% |
| Tiziana Life Sciences Ltd | -14.58 Million USD | 323.776% |
| Aurinia Pharmaceuticals Inc. | -91.69 Million USD | 135.598% |
| BriaCell Therapeutics Corp. | -4.79 Million USD | 781.211% |
| Monopar Therapeutics Inc. | -8.83 Million USD | 469.597% |
| Exelixis, Inc. | 170.88 Million USD | 80.899% |
| Better Therapeutics, Inc. | -38.26 Million USD | 185.307% |
| Nurix Therapeutics, Inc. | -155.06 Million USD | 121.05% |
| Apellis Pharmaceuticals, Inc. | -517.12 Million USD | 106.312% |
| NLS Pharmaceutics AG | -11.8 Million USD | 376.445% |
| Dermata Therapeutics, Inc. | -8.04 Million USD | 505.874% |
| Aridis Pharmaceuticals, Inc. | -29.99 Million USD | 208.825% |
| Gritstone bio, Inc. | -154.63 Million USD | 121.108% |
| Jasper Therapeutics, Inc. | -68.86 Million USD | 147.4% |
| TNF Pharmaceuticals, Inc. | -17.12 Million USD | 290.62% |
| Avid Bioservices, Inc. | -18.67 Million USD | 274.751% |
| Insmed Incorporated | -709.62 Million USD | 104.6% |
| Virpax Pharmaceuticals, Inc. | -15.68 Million USD | 308.033% |
| MediWound Ltd. | -15.29 Million USD | 313.473% |
| OmniAb, Inc. | -69.41 Million USD | 147.019% |
| Alector, Inc. | -151.74 Million USD | 121.51% |
| Seres Therapeutics, Inc. | -107.98 Million USD | 130.227% |
| Checkpoint Therapeutics, Inc. | -52.14 Million USD | 162.591% |
| Zai Lab Limited | -366.57 Million USD | 108.904% |
| Revance Therapeutics, Inc. | -316.77 Million USD | 110.304% |
| Aura Biosciences, Inc. | -84.99 Million USD | 138.404% |
| Lyell Immunopharma, Inc. | -245.49 Million USD | 113.295% |
| Immunic, Inc. | -99.22 Million USD | 132.896% |
| Tarsus Pharmaceuticals, Inc. | -143.15 Million USD | 122.8% |
| Veracyte, Inc. | -85.79 Million USD | 138.044% |
| InMed Pharmaceuticals Inc. | - USD | -Infinity% |
| FibroGen, Inc. | -281.81 Million USD | 111.582% |
| SeaStar Medical Holding Corporation | -14.21 Million USD | 329.697% |
| Adial Pharmaceuticals, Inc. | -6.88 Million USD | 573.871% |
| Sonnet BioTherapeutics Holdings, Inc. | -18.79 Million USD | 273.685% |
| Jazz Pharmaceuticals plc | 578.58 Million USD | 94.359% |
| Cyclacel Pharmaceuticals, Inc. | -25.45 Million USD | 228.236% |
| Amylyx Pharmaceuticals, Inc. | 38.8 Million USD | 15.881% |
| TG Therapeutics, Inc. | 20.63 Million USD | -58.193% |
| Galecto, Inc. | -39.9 Million USD | 181.794% |
| Calithera Biosciences, Inc. | -42.07 Million USD | 177.578% |
| Fortrea Holdings Inc. | 63.1 Million USD | 48.273% |
| KalVista Pharmaceuticals, Inc. | -140.44 Million USD | 123.24% |
| Aptevo Therapeutics Inc. | -28.87 Million USD | 213.027% |
| XBiotech Inc. | -37.51 Million USD | 187.017% |
| Jasper Therapeutics, Inc. | -68.86 Million USD | 147.4% |
| Lyra Therapeutics, Inc. | -67.12 Million USD | 148.629% |
| Foghorn Therapeutics Inc. | -107.9 Million USD | 130.249% |
| Y-mAbs Therapeutics, Inc. | -25.67 Million USD | 227.142% |
| Theravance Biopharma, Inc. | -53.29 Million USD | 161.247% |
| Ultragenyx Pharmaceutical Inc. | -569.2 Million USD | 105.734% |
| Metagenomi, Inc. Common Stock | -78.49 Million USD | 141.584% |
| Vaxxinity, Inc. | -58.28 Million USD | 156.001% |
| BioCryst Pharmaceuticals, Inc. | -103.7 Million USD | 131.473% |
| Gain Therapeutics, Inc. | -22.25 Million USD | 246.676% |
| Cartesian Therapeutics, Inc. | -86.41 Million USD | 137.771% |
| NexImmune, Inc. | -29.19 Million USD | 211.81% |
| Creative Medical Technology Holdings, Inc. | -5.62 Million USD | 680.769% |
| Marker Therapeutics, Inc. | -14.58 Million USD | 323.847% |
| Regeneron Pharmaceuticals, Inc. | 4.04 Billion USD | 99.193% |
| Chemomab Therapeutics Ltd. | -25.45 Million USD | 228.206% |
| Scopus BioPharma Inc. | -11.71 Million USD | 378.62% |
| RAPT Therapeutics, Inc. | -127.06 Million USD | 125.688% |
| Ainos, Inc. | -13.2 Million USD | 347.153% |
| Pluri Inc. | -22.15 Million USD | 247.306% |
| Prothena Corporation plc | -191.03 Million USD | 117.086% |
| Adaptimmune Therapeutics plc | -138.03 Million USD | 123.646% |
| Celularity Inc. | -192.28 Million USD | 116.975% |
| Rallybio Corporation | -78.93 Million USD | 141.352% |
| Cue Biopharma, Inc. | -52.14 Million USD | 162.59% |
| MeiraGTx Holdings plc | -137.06 Million USD | 123.814% |
| Omeros Corporation | -164.53 Million USD | 119.838% |
| Humacyte, Inc. | -100.04 Million USD | 132.625% |
| Immunocore Holdings plc | -59.64 Million USD | 154.72% |
| Cocrystal Pharma, Inc. | -18.55 Million USD | 275.872% |
| Cidara Therapeutics, Inc. | -24.48 Million USD | 233.317% |
| Blueprint Medicines Corporation | -486.27 Million USD | 106.712% |
| CalciMedica, Inc. | -21.87 Million USD | 249.211% |
| Cabaletta Bio, Inc. | -74.66 Million USD | 143.718% |
| Marinus Pharmaceuticals, Inc. | -131.48 Million USD | 124.824% |
| Scholar Rock Holding Corporation | -171.29 Million USD | 119.055% |
| Sana Biotechnology, Inc. | -326.9 Million USD | 109.985% |
| Pulmatrix, Inc. | -14.74 Million USD | 321.438% |
| Elicio Therapeutics, Inc. | -35.74 Million USD | 191.313% |
| Vigil Neuroscience, Inc. | -88.86 Million USD | 136.729% |
| Intellia Therapeutics, Inc. | -515.29 Million USD | 106.334% |
| Adlai Nortye Ltd. American Depositary Shares | -67.55 Million USD | 148.319% |
| Cytokinetics, Incorporated | -496.2 Million USD | 106.578% |
| Eloxx Pharmaceuticals, Inc. | -34.41 Million USD | 194.831% |
| Nutriband Inc. | -4.87 Million USD | 769.961% |
| Protara Therapeutics, Inc. | -43.61 Million USD | 174.84% |
| Vor Biopharma Inc. | -126.03 Million USD | 125.897% |
| Roivant Sciences Ltd. | 4.24 Billion USD | 99.231% |
| Evogene Ltd. | -26.39 Million USD | 223.679% |
| ProKidney Corp. | -151.52 Million USD | 121.541% |
| Applied Therapeutics, Inc. | -64.53 Million USD | 150.577% |
| Hoth Therapeutics, Inc. | -7.69 Million USD | 524.324% |
| BridgeBio Pharma, Inc. | -607.37 Million USD | 105.374% |
| CorMedix Inc. | -48.95 Million USD | 166.67% |
| BioLineRx Ltd. | -49.69 Million USD | 165.682% |
| Tango Therapeutics, Inc. | -114.17 Million USD | 128.588% |
| Galectin Therapeutics Inc. | -38.07 Million USD | 185.732% |
| Atai Life Sciences N.V. | -125.47 Million USD | 126.014% |
| Renovaro Biosciences Inc. | -81.63 Million USD | 139.981% |
| Aerovate Therapeutics, Inc. | -81.4 Million USD | 140.094% |
| Zentalis Pharmaceuticals, Inc. | -248.98 Million USD | 113.109% |
| Sagimet Biosciences Inc. | -30.74 Million USD | 206.181% |
| MediciNova, Inc. | -9.9 Million USD | 429.688% |
| Praxis Precision Medicines, Inc. | -126.37 Million USD | 125.828% |
| Cardio Diagnostics Holdings, Inc. | -7.24 Million USD | 550.676% |
| GeoVax Labs, Inc. | -26.74 Million USD | 222.051% |
| Axsome Therapeutics, Inc. | -231.82 Million USD | 114.08% |
| Biomea Fusion, Inc. | -126.13 Million USD | 125.877% |
| PTC Therapeutics, Inc. | -349.4 Million USD | 109.342% |
| Mereo BioPharma Group plc | -28.41 Million USD | 214.865% |
| Cullinan Oncology, Inc. | -191.08 Million USD | 117.081% |
| Syndax Pharmaceuticals, Inc. | -229.95 Million USD | 114.194% |
| Absci Corporation | -115.51 Million USD | 128.256% |
| NRx Pharmaceuticals, Inc. | -27.58 Million USD | 218.317% |
| 4D Molecular Therapeutics, Inc. | -112.86 Million USD | 128.919% |
| Dyne Therapeutics, Inc. | -242.16 Million USD | 113.479% |
| Kiniksa Pharmaceuticals, Ltd. | -25.19 Million USD | 229.544% |
| Ventyx Biosciences, Inc. | -207.99 Million USD | 115.693% |
| Allakos Inc. | -196.05 Million USD | 116.648% |
| Imunon, Inc. | -21.03 Million USD | 255.204% |
| Fulcrum Therapeutics, Inc. | -110.66 Million USD | 129.495% |
| Corcept Therapeutics Incorporated | 107.28 Million USD | 69.576% |
| BioAtla, Inc. | -129.68 Million USD | 125.168% |
| NLS Pharmaceutics AG | -11.8 Million USD | 376.445% |
| Bio-Path Holdings, Inc. | -15.84 Million USD | 306.022% |
| Allogene Therapeutics, Inc. | -327.73 Million USD | 109.959% |
| Larimar Therapeutics, Inc. | -41.75 Million USD | 178.165% |
| XOMA Corporation | -41.84 Million USD | 177.997% |
| Kezar Life Sciences, Inc. | -105.23 Million USD | 131.016% |
| Cara Therapeutics, Inc. | -121.49 Million USD | 126.865% |
| aTyr Pharma, Inc. | -54.91 Million USD | 159.433% |
| Aligos Therapeutics, Inc. | -87.42 Million USD | 137.334% |
| Akero Therapeutics, Inc. | -172.87 Million USD | 118.881% |
| Viridian Therapeutics, Inc. | -254.45 Million USD | 112.828% |
| Eliem Therapeutics, Inc. | -21.46 Million USD | 252.054% |
| EyeGate Pharmaceuticals, Inc. | -8.21 Million USD | 497.431% |
| Akari Therapeutics, Plc | -16.8 Million USD | 294.216% |
| Tevogen Bio Holdings Inc. | -8843.03 USD | 369204.255% |
| Halozyme Therapeutics, Inc. | 337.57 Million USD | 90.331% |
| Lexaria Bioscience Corp. | -6.53 Million USD | 599.539% |
| UroGen Pharma Ltd. | -65.53 Million USD | 149.805% |
| Sutro Biopharma, Inc. | -89.27 Million USD | 136.56% |
| ZIVO Bioscience, Inc. | -7.26 Million USD | 549.4% |
| Orgenesis Inc. | -53.63 Million USD | 160.855% |
| Entera Bio Ltd. | -8.89 Million USD | 467.113% |
| GH Research PLC | -41.22 Million USD | 179.181% |
| Lisata Therapeutics, Inc. | -25.7 Million USD | 226.964% |
| Reneo Pharmaceuticals, Inc. | -83.05 Million USD | 139.3% |
| Xencor, Inc. | -138.63 Million USD | 123.543% |
| 60 Degrees Pharmaceuticals, Inc. | -5.15 Million USD | 733.223% |
| Replimune Group, Inc. | -234.77 Million USD | 113.903% |
| Coeptis Therapeutics Holdings, Inc. | -21.49 Million USD | 251.877% |
| Vanda Pharmaceuticals Inc. | -13.95 Million USD | 333.945% |
| Lexaria Bioscience Corp. | -6.53 Million USD | 599.539% |
| Portage Biotech Inc. | -18.25 Million USD | 278.82% |
| Cardio Diagnostics Holdings, Inc. | -7.24 Million USD | 550.676% |
| Olema Pharmaceuticals, Inc. | -104.96 Million USD | 131.097% |
| OncoCyte Corporation | -25.13 Million USD | 229.854% |
| Qualigen Therapeutics, Inc. | -11.3 Million USD | 388.725% |
| Processa Pharmaceuticals, Inc. | -11.45 Million USD | 384.89% |
| Purple Biotech Ltd. | 22.27 Million USD | -46.558% |
| CollPlant Biotechnologies Ltd. | -7.51 Million USD | 534.505% |
| scPharmaceuticals Inc. | -55.39 Million USD | 158.921% |
| ProMIS Neurosciences, Inc. | -18.89 Million USD | 272.719% |
| HilleVax, Inc. | -133.34 Million USD | 124.478% |
| NeuroSense Therapeutics Ltd. | -12.04 Million USD | 370.894% |
| Tharimmune, Inc. | -9.45 Million USD | 445.206% |
| Genprex, Inc. | -31.07 Million USD | 205.034% |
| Neumora Therapeutics, Inc. Common Stock | -188.19 Million USD | 117.344% |
| Atossa Therapeutics, Inc. | -31.37 Million USD | 204.025% |
| XTL Biopharmaceuticals Ltd. | -765 Thousand USD | 4366.667% |
| Virios Therapeutics, Inc. | -5.44 Million USD | 699.238% |
| OKYO Pharma Limited | -15.74 Thousand USD | 207341.648% |
| Savara Inc. | -60 Million USD | 154.394% |
| Curis, Inc. | -48.33 Million USD | 167.533% |
| Daré Bioscience, Inc. | -30.83 Million USD | 205.837% |
| Carmell Therapeutics Corporation | -5.21 Million USD | 725.613% |
| Titan Pharmaceuticals, Inc. | -7.27 Million USD | 548.536% |
| Achieve Life Sciences, Inc. | -27.25 Million USD | 219.78% |
| BeiGene, Ltd. | -1.2 Billion USD | 102.703% |
| Kiromic BioPharma, Inc. | -19.93 Million USD | 263.697% |
| Revolution Medicines, Inc. Warrant | -487.18 Million USD | 106.7% |
| Protagonist Therapeutics, Inc. | -93.65 Million USD | 134.852% |
| Erasca, Inc. | -141.52 Million USD | 123.063% |
| bluebird bio, Inc. | -244.26 Million USD | 113.363% |
| Protagenic Therapeutics, Inc. | -4.52 Million USD | 821.011% |
| BioMarin Pharmaceutical Inc. | 194.44 Million USD | 83.213% |
| DBV Technologies S.A. | -76.43 Million USD | 142.705% |
| Protagenic Therapeutics, Inc. | -4.52 Million USD | 821.011% |
| Moderna, Inc. | -4.23 Billion USD | 100.77% |
| Vincerx Pharma, Inc. | -42.6 Million USD | 176.604% |
| Fresh Tracks Therapeutics, Inc. | -6.36 Million USD | 613.208% |
| Molecular Templates, Inc. | -10.46 Million USD | 411.867% |
| Acrivon Therapeutics, Inc. Common Stock | -67.23 Million USD | 148.545% |
| Travere Therapeutics, Inc. | -376.74 Million USD | 108.664% |
| Monte Rosa Therapeutics, Inc. | -143.31 Million USD | 122.776% |
| Spruce Biosciences, Inc. | -51.99 Million USD | 162.778% |
| Celldex Therapeutics, Inc. | -154.54 Million USD | 121.12% |
| Cogent Biosciences, Inc. | -208.13 Million USD | 115.683% |
| MacroGenics, Inc. | -168.24 Million USD | 119.4% |
| RenovoRx, Inc. | -11.39 Million USD | 386.416% |
| Adicet Bio, Inc. | -152.03 Million USD | 121.468% |
| Prime Medicine, Inc. | -191.29 Million USD | 117.063% |
| Aditxt, Inc. | -26.06 Million USD | 225.238% |
| Adagene Inc. | -23.71 Million USD | 237.606% |
| Estrella Immunopharma, Inc. | -7.31 Million USD | 546.506% |
| Quantum-Si incorporated | -111.17 Million USD | 129.36% |
| Maravai LifeSciences Holdings, Inc. | -31.64 Million USD | 203.134% |
| Acurx Pharmaceuticals, Inc. | -14.57 Million USD | 323.903% |
| Voyager Therapeutics, Inc. | 122.01 Million USD | 73.249% |
| SciSparc Ltd. | -5.77 Million USD | 665.391% |
| Vericel Corporation | -6.46 Million USD | 604.95% |
| Revelation Biosciences, Inc. | -8.65 Million USD | 477.051% |
| Minerva Neurosciences, Inc. | -23.11 Million USD | 241.179% |
| Generation Bio Co. | -138.56 Million USD | 123.556% |
| Astria Therapeutics, Inc. | -83.03 Million USD | 139.311% |
| Black Diamond Therapeutics, Inc. | -86.46 Million USD | 137.752% |
| Arcutis Biotherapeutics, Inc. | -241.1 Million USD | 113.538% |
| Invivyd, Inc. | -207.78 Million USD | 115.709% |
| Relay Therapeutics, Inc. | -373 Million USD | 108.751% |
| Quoin Pharmaceuticals, Ltd. | -9.37 Million USD | 448.03% |
| Spero Therapeutics, Inc. | 21.48 Million USD | -51.948% |
| Artelo Biosciences, Inc. | -10.28 Million USD | 417.294% |
| 2seventy bio, Inc. | -216.7 Million USD | 115.062% |
| ADMA Biologics, Inc. | 21.63 Million USD | -50.888% |
| Clene Inc. | -40.54 Million USD | 180.513% |
| Capricor Therapeutics, Inc. | -24.07 Million USD | 235.56% |
| Boundless Bio, Inc. Common Stock | -54.79 Million USD | 159.566% |
| GeoVax Labs, Inc. | -26.74 Million USD | 222.051% |
| Recursion Pharmaceuticals, Inc. | -350.06 Million USD | 109.324% |
| Citius Pharmaceuticals, Inc. | -36.73 Million USD | 188.86% |
| Contineum Therapeutics, Inc. Class A Common Stock | 16.07 Million USD | -103.023% |
| Relmada Therapeutics, Inc. | -103.7 Million USD | 131.475% |
| Finch Therapeutics Group, Inc. | -34 Million USD | 195.994% |
| ALX Oncology Holdings Inc. | -170.27 Million USD | 119.169% |
| Vir Biotechnology, Inc. | -684.3 Million USD | 104.77% |
| Evaxion Biotech A/S | -22.19 Million USD | 247.047% |
| Ocular Therapeutix, Inc. | -82.38 Million USD | 139.62% |
| Verve Therapeutics, Inc. | -223.12 Million USD | 114.629% |
| Trevena, Inc. | -35.28 Million USD | 192.496% |
| Surrozen, Inc. | -45.78 Million USD | 171.298% |
| Tyra Biosciences, Inc. | -79.94 Million USD | 140.828% |
| Cingulate Inc. | -22.75 Million USD | 243.415% |
| Galmed Pharmaceuticals Ltd. | 7.49 Million USD | -335.665% |
| Unity Biotechnology, Inc. | -44.66 Million USD | 173.074% |
| Tenax Therapeutics, Inc. | -8.23 Million USD | 496.408% |
| Terns Pharmaceuticals, Inc. | -102.55 Million USD | 131.826% |
| ACADIA Pharmaceuticals Inc. | -73.37 Million USD | 144.481% |
| Connect Biopharma Holdings Limited | -62.07 Million USD | 152.582% |
| Clearmind Medicine Inc. | -8.74 Million USD | 473.398% |
| Kronos Bio, Inc. | -121.83 Million USD | 126.791% |
| Bolt Biotherapeutics, Inc. | -76.19 Million USD | 142.837% |
| CERo Therapeutics Holdings, Inc. | -2.93 Million USD | 1212.859% |
| Viking Therapeutics, Inc. | -100.82 Million USD | 132.372% |
| Statera Biopharma, Inc. | -98.34 Million USD | 133.19% |
| ImmunityBio, Inc. | -362.25 Million USD | 109.01% |
| Korro Bio, Inc. | -84.53 Million USD | 138.612% |
| Kineta, Inc. | -15.72 Million USD | 307.594% |
| BioVie Inc. | -32.17 Million USD | 201.431% |
| Codexis, Inc. | -68.06 Million USD | 147.951% |
| Celularity Inc. | -192.28 Million USD | 116.975% |
| Crinetics Pharmaceuticals, Inc. | -222.6 Million USD | 114.663% |
| Celcuity Inc. | -66.23 Million USD | 149.283% |
| Virax Biolabs Group Limited | -6.49 Million USD | 602.426% |
| Cibus, Inc. | -318.88 Million USD | 110.236% |
| Eledon Pharmaceuticals, Inc. | -43 Million USD | 175.907% |
| eFFECTOR Therapeutics, Inc. | -33.84 Million USD | 196.443% |
| IN8bio, Inc. | -30.33 Million USD | 207.591% |
| Kodiak Sciences Inc. | -277.32 Million USD | 111.77% |
| Annexon, Inc. | -143.72 Million USD | 122.71% |
| Adverum Biotechnologies, Inc. | -123.79 Million USD | 126.367% |
| Assembly Biosciences, Inc. | -64.64 Million USD | 150.49% |
| Avalo Therapeutics, Inc. | -23.44 Million USD | 239.225% |
| Ionis Pharmaceuticals, Inc. | -353.73 Million USD | 109.227% |
| Eyenovia, Inc. | -25.4 Million USD | 228.471% |
| Conduit Pharmaceuticals Inc. | -5.56 Million USD | 686.839% |
| Xilio Therapeutics, Inc. | -79.13 Million USD | 141.247% |
| Arcellx, Inc. | -89.88 Million USD | 136.315% |
| Cardiff Oncology, Inc. | -45.41 Million USD | 171.875% |
| Enanta Pharmaceuticals, Inc. | -137.2 Million USD | 123.789% |
| Regulus Therapeutics Inc. | -31.1 Million USD | 204.921% |
| Moolec Science SA | -6.65 Million USD | 590.546% |
| Acumen Pharmaceuticals, Inc. | -61.13 Million USD | 153.387% |
| Geron Corporation | -193.94 Million USD | 116.83% |
| LAVA Therapeutics N.V. | -43.25 Million USD | 175.463% |
| Royalty Pharma plc | 1.49 Billion USD | 97.813% |
| Atea Pharmaceuticals, Inc. | -164.16 Million USD | 119.883% |
| Greenwich LifeSciences, Inc. | -9.32 Million USD | 449.919% |
| TFF Pharmaceuticals, Inc. | -21.89 Million USD | 249.077% |
| Mersana Therapeutics, Inc. | -170.95 Million USD | 119.093% |
| Humacyte, Inc. | -100.04 Million USD | 132.625% |
| Structure Therapeutics Inc. | -102.77 Million USD | 131.759% |
| 89bio, Inc. | -151.2 Million USD | 121.587% |
| PMV Pharmaceuticals, Inc. | -80.13 Million USD | 140.733% |
| Avenue Therapeutics, Inc. | -14.54 Million USD | 324.484% |
| Genelux Corporation | -24.16 Million USD | 235.071% |
| Trevi Therapeutics, Inc. | -33.92 Million USD | 196.218% |
| Lexicon Pharmaceuticals, Inc. | -171.75 Million USD | 119.004% |
| Notable Labs, Ltd. | -14.65 Million USD | 322.692% |
| Liquidia Corporation | -73.38 Million USD | 144.478% |
| Mustang Bio, Inc. | -50.72 Million USD | 164.346% |
| Immunovant, Inc. | -282.7 Million USD | 111.545% |
| Quantum-Si incorporated | -111.17 Million USD | 129.36% |
| Arbutus Biopharma Corporation | -78.1 Million USD | 141.791% |
| DiaMedica Therapeutics Inc. | -21.26 Million USD | 253.477% |
| Vera Therapeutics, Inc. | -102.01 Million USD | 131.996% |
| Acasti Pharma Inc. | -11.31 Million USD | 388.543% |
| MiNK Therapeutics, Inc. | -22.92 Million USD | 242.402% |
| Pasithea Therapeutics Corp. | -15.97 Million USD | 304.263% |
| Xenon Pharmaceuticals Inc. | -214.05 Million USD | 115.248% |
| Elevai Labs, Inc. Common Stock | -3.66 Million USD | 989.598% |
| NeuroBo Pharmaceuticals, Inc. | -15.88 Million USD | 305.464% |
| Tempest Therapeutics, Inc. | -29.15 Million USD | 211.946% |
| Soleno Therapeutics, Inc. | -41.38 Million USD | 178.871% |
| PepGen Inc. | -84.76 Million USD | 138.506% |
| Moleculin Biotech, Inc. | -29.63 Million USD | 210.155% |
| United Therapeutics Corporation | 1.18 Billion USD | 97.245% |
| Nuvectis Pharma, Inc. | -22.89 Million USD | 242.551% |
| Solid Biosciences Inc. | -104.31 Million USD | 131.29% |
| BriaCell Therapeutics Corp. | -32.8 Million USD | 199.488% |
| Immuneering Corporation | -58.41 Million USD | 155.878% |
| Lixte Biotechnology Holdings, Inc. | -5.09 Million USD | 741.228% |
| Silo Pharma, Inc. | -3.85 Million USD | 946.563% |
| Belite Bio, Inc | -31.66 Million USD | 203.069% |
| XOMA Corporation | -41.84 Million USD | 177.997% |
| ARS Pharmaceuticals, Inc. | -67.52 Million USD | 148.341% |
| Bionomics Limited | -17.89 Billion USD | 100.182% |
| Apogee Therapeutics, Inc. | -93 Million USD | 135.096% |
| Alpha Tau Medical Ltd. | 35.68 Million USD | 8.52% |
| uniQure N.V. | -282.87 Million USD | 111.539% |
| Cassava Sciences, Inc. | -105.95 Million USD | 130.805% |
| Estrella Immunopharma, Inc. | -7.31 Million USD | 546.506% |
| Poseida Therapeutics, Inc. | -129.5 Million USD | 125.204% |
| Forte Biosciences, Inc. | -32.48 Million USD | 200.474% |
| Anebulo Pharmaceuticals, Inc. | -8.3 Million USD | 492.839% |
| Enlivex Therapeutics Ltd. | -29.39 Million USD | 211.039% |
| Conduit Pharmaceuticals Inc. | -5.56 Million USD | 686.839% |
| SeaStar Medical Holding Corporation | -14.21 Million USD | 329.697% |
| FibroBiologics, Inc. Common Stock | -8.88 Million USD | 467.195% |
| Altimmune, Inc. | -95.92 Million USD | 134.025% |
| Amicus Therapeutics, Inc. | -73.49 Million USD | 144.412% |
| Alpha Tau Medical Ltd. | 35.68 Million USD | 8.52% |
| Compugen Ltd. | -12.99 Million USD | 351.232% |
| Peak Bio, Inc. | -1356.23 USD | 2406771.435% |
| Zevra Therapeutics, Inc. | -49.6 Million USD | 165.801% |
| Benitec Biopharma Inc. | -22.49 Million USD | 245.131% |
| Spyre Therapeutics, Inc. | -242.3 Million USD | 113.471% |
| NKGen Biotech, Inc. Common Stock | -29.74 Million USD | 209.729% |
| Zura Bio Limited | -62.63 Million USD | 152.109% |
| PolyPid Ltd. | -22.86 Million USD | 242.738% |
| Aileron Therapeutics, Inc. | -16.27 Million USD | 300.541% |
| NKGen Biotech, Inc. Warrants | -29.74 Million USD | 209.729% |
| Instil Bio, Inc. | -159.16 Million USD | 120.507% |
| argenx SE | -425.04 Million USD | 107.679% |
| Immunome, Inc. | -109.53 Million USD | 129.8% |
| Compass Therapeutics, Inc. | -50.36 Million USD | 164.809% |
| Verona Pharma plc | -67.83 Million USD | 148.12% |
| enGene Holdings Inc. Warrants | -26.06 Million USD | 225.249% |
| Shattuck Labs, Inc. | -91.95 Million USD | 135.495% |
| CervoMed Inc. | -7.81 Million USD | 517.771% |
| LENZ Therapeutics, Inc. | -73.11 Million USD | 144.645% |
| Plus Therapeutics, Inc. | -13.32 Million USD | 345.027% |
| Dianthus Therapeutics, Inc. | -48.17 Million USD | 167.754% |
| Moolec Science SA | -6.65 Million USD | 590.546% |
| Enveric Biosciences, Inc. | -16.44 Million USD | 298.438% |
| Inovio Pharmaceuticals, Inc. | -135.22 Million USD | 124.137% |
| AnaptysBio, Inc. | -164.41 Million USD | 119.853% |
| Design Therapeutics, Inc. | -78.19 Million USD | 141.744% |
| Leap Therapeutics, Inc. | -87.04 Million USD | 137.5% |
| NeurAxis, Inc. | -6.66 Million USD | 589.76% |
| Seelos Therapeutics, Inc. | -40.49 Million USD | 180.595% |
| Lumos Pharma, Inc. | -36.61 Million USD | 189.146% |
| Achilles Therapeutics plc | -75.25 Million USD | 143.373% |
| enGene Holdings Inc. Common Stock | -26.06 Million USD | 225.249% |
| 180 Life Sciences Corp. | -13.47 Million USD | 342.181% |
| Opiant Pharmaceuticals, Inc. | 5.15 Million USD | -533.011% |
| CERo Therapeutics Holdings, Inc. | -2.93 Million USD | 1212.859% |
| Nutriband Inc. | -4.87 Million USD | 769.961% |
| ORIC Pharmaceuticals, Inc. | -110.78 Million USD | 129.464% |
| CG Oncology, Inc. Common stock | -55.44 Million USD | 158.865% |
| Fractyl Health, Inc. Common Stock | -50.83 Million USD | 164.206% |
| Rani Therapeutics Holdings, Inc. | -66.09 Million USD | 149.38% |
| MoonLake Immunotherapeutics | -54.12 Million USD | 160.307% |
| Palisade Bio, Inc. | -13.07 Million USD | 349.732% |
| Tourmaline Bio, Inc. | -45.4 Million USD | 171.88% |
| Beam Therapeutics Inc. | -176.48 Million USD | 118.494% |
| Neurogene Inc. | -55.58 Million USD | 158.723% |
| Mirum Pharmaceuticals, Inc. | -109.15 Million USD | 129.903% |
| AEON Biopharma, Inc. | -48.42 Million USD | 167.398% |
| CARGO Therapeutics, Inc. Common Stock | -96.71 Million USD | 133.75% |
| Sesen Bio, Inc. | -25.9 Million USD | 225.979% |
| Enliven Therapeutics, Inc. | -83.52 Million USD | 139.076% |
| Kiora Pharmaceuticals, Inc. | -12.58 Million USD | 359.317% |
| Iovance Biotherapeutics, Inc. | -460.55 Million USD | 107.087% |
| Taysha Gene Therapies, Inc. | -72.43 Million USD | 145.059% |
| Athira Pharma, Inc. | -125.46 Million USD | 126.015% |
| Vaccinex, Inc. | -22.88 Million USD | 242.626% |
| HCW Biologics Inc. | -25.71 Million USD | 226.919% |
| XOMA Corporation | -41.84 Million USD | 177.997% |
| Nektar Therapeutics | -137.42 Million USD | 123.751% |
| Arvinas, Inc. | -401.5 Million USD | 108.13% |
| Tevogen Bio Holdings Inc. | -8843.03 USD | 369204.255% |
| Merus N.V. | -156.54 Million USD | 120.85% |
| Omega Therapeutics, Inc. | -100.26 Million USD | 132.555% |
| Quince Therapeutics, Inc. | -34.62 Million USD | 194.281% |
| Rezolute, Inc. | -70.42 Million USD | 146.348% |
| Clene Inc. | -40.54 Million USD | 180.513% |
| Indaptus Therapeutics, Inc. | -16.37 Million USD | 299.286% |
| BeyondSpring Inc. | -23.11 Million USD | 241.213% |
| Synlogic, Inc. | -55.16 Million USD | 159.172% |
| Allarity Therapeutics, Inc. | -17.92 Million USD | 282.051% |
| Phio Pharmaceuticals Corp. | -10.82 Million USD | 401.552% |
| Peak Bio, Inc. | -1356.23 USD | 2406771.435% |
| Werewolf Therapeutics, Inc. | -40.5 Million USD | 180.587% |
| Krystal Biotech, Inc. | -109.72 Million USD | 129.747% |
| Karyopharm Therapeutics Inc. | -129.53 Million USD | 125.197% |
| SpringWorks Therapeutics, Inc. | -343.01 Million USD | 109.516% |
| Lipella Pharmaceuticals Inc. | -4.74 Million USD | 787.744% |
| MannKind Corporation | 8.67 Million USD | -276.124% |
| Ikena Oncology, Inc. | -75.41 Million USD | 143.279% |
| Cyclerion Therapeutics, Inc. | -9.64 Million USD | 438.344% |
| Gyre Therapeutics, Inc. | -67.23 Million USD | 148.55% |
| Gossamer Bio, Inc. | -183.75 Million USD | 117.762% |
| CohBar, Inc. | -12.38 Million USD | 363.474% |
| Cognition Therapeutics, Inc. | -50.72 Million USD | 164.348% |
| NRx Pharmaceuticals, Inc. | -27.58 Million USD | 218.317% |
| Legend Biotech Corporation | -439.48 Million USD | 107.427% |
| Mural Oncology plc | -194.63 Million USD | 116.77% |
| Biora Therapeutics, Inc. | -67.14 Million USD | 148.613% |
| PaxMedica, Inc. Common Stock | -16.14 Million USD | 302.164% |
| Disc Medicine, Inc. | -91.12 Million USD | 135.819% |
| Champions Oncology, Inc. | -7.35 Million USD | 543.719% |
| REGENXBIO Inc. | -268.12 Million USD | 112.173% |
| Ensysce Biosciences, Inc. | -10.71 Million USD | 404.529% |
| Anavex Life Sciences Corp. | -55.75 Million USD | 158.541% |
| Cellectar Biosciences, Inc. | -38.96 Million USD | 183.777% |
| Edgewise Therapeutics, Inc. | -114.35 Million USD | 128.542% |
| Vaxart, Inc. | -83.34 Million USD | 139.162% |
| PharmaCyte Biotech, Inc. | -8.52 Million USD | 483.098% |
| Aldeyra Therapeutics, Inc. | -42.79 Million USD | 176.272% |
| Cellectis S.A. | -106.62 Million USD | 130.612% |
| Longeveron Inc. | -21.02 Million USD | 255.214% |
| Repare Therapeutics Inc. | -116.22 Million USD | 128.084% |
| Sarepta Therapeutics, Inc. | -267.82 Million USD | 112.187% |
| Inozyme Pharma, Inc. | -75.64 Million USD | 143.149% |
| Revolution Medicines, Inc. | -487.18 Million USD | 106.7% |
| Nymox Pharmaceutical Corporation | -6.65 Million USD | 590.679% |
| Third Harmonic Bio, Inc. | -43.95 Million USD | 174.259% |
| ArriVent BioPharma, Inc. Common Stock | -74.59 Million USD | 143.759% |
| AN2 Therapeutics, Inc. | -69.63 Million USD | 146.873% |
| Anixa Biosciences, Inc. | -11.01 Million USD | 396.431% |
| Vertex Pharmaceuticals Incorporated | 4.3 Billion USD | 99.242% |
| Denali Therapeutics Inc. | -196.69 Million USD | 116.594% |
| Revelation Biosciences, Inc. | -8.65 Million USD | 477.051% |
| Veru Inc. | -93.78 Million USD | 134.804% |
| Corvus Pharmaceuticals, Inc. | -23.32 Million USD | 239.912% |
| Cingulate Inc. | -22.75 Million USD | 243.415% |
| Passage Bio, Inc. | -108.38 Million USD | 130.114% |
| Context Therapeutics Inc. | -25.07 Million USD | 230.182% |
| Exicure, Inc. | -14.99 Million USD | 317.658% |
| Day One Biopharmaceuticals, Inc. | -206.06 Million USD | 115.84% |
| Oramed Pharmaceuticals Inc. | -40.59 Million USD | 180.398% |
| Scinai Immunotherapeutics Ltd. | -9.71 Million USD | 435.908% |
| Rhythm Pharmaceuticals, Inc. | -184.35 Million USD | 117.705% |
| Nuvalent, Inc. | -149.49 Million USD | 121.834% |
| ABVC BioPharma, Inc. | -8.21 Million USD | 497.249% |
| Carisma Therapeutics, Inc. | -88.73 Million USD | 136.785% |
| Unicycive Therapeutics, Inc. | -20.77 Million USD | 257.119% |
| OmniAb, Inc. | -69.41 Million USD | 147.019% |
| Anew Medical, Inc. | -1.3 Million USD | 2609.148% |
| Fennec Pharmaceuticals Inc. | -12.77 Million USD | 355.579% |
| Lipocine Inc. | -17.93 Million USD | 282.032% |
| Lexeo Therapeutics, Inc. Common Stock | -68.51 Million USD | 147.641% |
| Nautilus Biotechnology, Inc. | -76.15 Million USD | 142.862% |
| SAB Biotherapeutics, Inc. | -38.07 Million USD | 185.725% |
| G1 Therapeutics, Inc. | -39.52 Million USD | 182.576% |
| Bellerophon Therapeutics, Inc. | -22.38 Million USD | 245.818% |
| Sage Therapeutics, Inc. | -579.84 Million USD | 105.629% |
| Ocugen, Inc. | -65.53 Million USD | 149.808% |
| Mind Medicine (MindMed) Inc. | -93.86 Million USD | 134.773% |
| Q32 Bio Inc. | -92.1 Million USD | 135.439% |
| Brainstorm Cell Therapeutics Inc. | -21.43 Million USD | 252.246% |
| Alumis Inc. Common Stock | -158.17 Million USD | 120.636% |
| Equillium, Inc. | -14.52 Million USD | 324.762% |
| Kyverna Therapeutics, Inc. | -62.4 Million USD | 152.303% |
| Coya Therapeutics, Inc. | -7.9 Million USD | 512.989% |
| CNS Pharmaceuticals, Inc. | -18.86 Million USD | 273.018% |
| Galera Therapeutics, Inc. | -46.95 Million USD | 169.519% |
| Evelo Biosciences, Inc. | -108.46 Million USD | 130.092% |
| Comera Life Sciences Holdings, Inc. | -11.97 Million USD | 372.681% |
| Dominari Holdings Inc. | -21.79 Million USD | 249.752% |
| Edesa Biotech, Inc. | -9.22 Million USD | 453.907% |
| vTv Therapeutics Inc. | -25.5 Million USD | 227.99% |
| Bio-Techne Corporation | 206.68 Million USD | 84.208% |
| Agios Pharmaceuticals, Inc. | -391.48 Million USD | 108.337% |
| Harmony Biosciences Holdings, Inc. | 192.03 Million USD | 83.003% |
| Prelude Therapeutics Incorporated | -132.27 Million USD | 124.675% |
| Candel Therapeutics, Inc. | -38.39 Million USD | 185.02% |
| iTeos Therapeutics, Inc. | -151.1 Million USD | 121.601% |
| Nkarta, Inc. | -131.65 Million USD | 124.793% |
| BioCardia, Inc. | -11.64 Million USD | 380.316% |
| Iterum Therapeutics plc | -47.46 Million USD | 168.762% |