Spruce Biosciences, Inc. (SPRB)
USD 0.28
(0.53%)
USD 0.28
(0.53%)
| Year | Operating Income | Operating Income Growth |
|---|---|---|
| 2023 | -51.99 Million USD | -9.96% |
| 2022 | -47.28 Million USD | -12.4% |
| 2021 | -42.06 Million USD | -43.0% |
| 2020 | -29.41 Million USD | -124.43% |
| 2019 | -13.1 Million USD | -31.44% |
| 2018 | -9.97 Million USD | 0.0% |
| Year | Operating Income | Operating Income Growth |
|---|---|---|
| 2024 Q1 | -12.63 Million USD | -13.16% |
| 2024 Q2 | -10.03 Million USD | 20.56% |
| 2023 Q4 | -11.16 Million USD | 18.26% |
| 2023 FY | -51.99 Million USD | -9.96% |
| 2023 Q1 | -13.19 Million USD | -8.99% |
| 2023 Q2 | -13.97 Million USD | -5.86% |
| 2023 Q3 | -13.65 Million USD | 2.25% |
| 2022 Q3 | -11.55 Million USD | 2.74% |
| 2022 Q1 | -11.73 Million USD | -28.44% |
| 2022 FY | -47.28 Million USD | -12.4% |
| 2022 Q2 | -11.88 Million USD | -1.27% |
| 2022 Q4 | -12.11 Million USD | -4.78% |
| 2021 Q1 | -9.81 Million USD | -17.79% |
| 2021 FY | -42.06 Million USD | -43.0% |
| 2021 Q4 | -9.13 Million USD | 19.87% |
| 2021 Q3 | -11.4 Million USD | 2.68% |
| 2021 Q2 | -11.71 Million USD | -19.32% |
| 2020 FY | -29.41 Million USD | -124.43% |
| 2020 Q4 | -8.33 Million USD | 12.82% |
| 2020 Q3 | -9.55 Million USD | -49.62% |
| 2020 Q2 | -6.38 Million USD | -24.47% |
| 2020 Q1 | -5.13 Million USD | -63.78% |
| 2019 Q3 | -2.56 Million USD | 30.79% |
| 2019 Q4 | -3.13 Million USD | -22.23% |
| 2019 FY | -13.1 Million USD | -31.44% |
| 2019 Q1 | -3.7 Million USD | 0.0% |
| 2019 Q2 | -3.7 Million USD | 0.0% |
| 2018 FY | -9.97 Million USD | 0.0% |
| Name | Operating Income | Operating Income Difference |
|---|---|---|
| Alnylam Pharmaceuticals, Inc. | -282.17 Million USD | 81.574% |
| AlloVir, Inc. | -181.33 Million USD | 71.327% |
| Aptorum Group Limited | -10.52 Million USD | -394.074% |
| Ardelyx, Inc. | -63.27 Million USD | 17.831% |
| Arrowhead Pharmaceuticals, Inc. | -205 Million USD | 74.638% |
| Bicycle Therapeutics plc | -189.94 Million USD | 72.627% |
| AbCellera Biologics Inc. | -237.2 Million USD | 78.081% |
| BioXcel Therapeutics, Inc. | -171.78 Million USD | 69.733% |
| Chimerix, Inc. | -93.06 Million USD | 44.133% |
| Corbus Pharmaceuticals Holdings, Inc. | -45.07 Million USD | -15.342% |
| Elevation Oncology, Inc. | -45.44 Million USD | -14.409% |
| Alkermes plc | 414.12 Million USD | 112.555% |
| Fortress Biotech, Inc. | -142.34 Million USD | 63.473% |
| Fortress Biotech, Inc. | -142.34 Million USD | 63.473% |
| Agenus Inc. | -159.54 Million USD | 67.413% |
| HOOKIPA Pharma Inc. | -97.69 Million USD | 46.78% |
| Dyadic International, Inc. | -8.22 Million USD | -531.77% |
| ImmuCell Corporation | -5.74 Million USD | -804.528% |
| Eton Pharmaceuticals, Inc. | -1.19 Million USD | -4261.829% |
| IDEAYA Biosciences, Inc. | -134.42 Million USD | 61.323% |
| Lantern Pharma Inc. | -17.87 Million USD | -190.828% |
| Immix Biopharma, Inc. | -16.14 Million USD | -222.115% |
| Incyte Corporation | 620.52 Million USD | 108.379% |
| IO Biotech, Inc. | -91.44 Million USD | 43.142% |
| Janux Therapeutics, Inc. | -72.97 Million USD | 28.756% |
| Inhibikase Therapeutics, Inc. | -20.08 Million USD | -158.803% |
| Outlook Therapeutics, Inc. | -53.12 Million USD | 2.133% |
| Syros Pharmaceuticals, Inc. | -128.98 Million USD | 59.692% |
| Keros Therapeutics, Inc. | -169.94 Million USD | 69.405% |
| Kintara Therapeutics, Inc. | -8.5 Million USD | -511.61% |
| Longboard Pharmaceuticals, Inc. | -56.75 Million USD | 8.397% |
| Ligand Pharmaceuticals Incorporated | 11.94 Million USD | 535.379% |
| ContextLogic Inc. | -328 Million USD | 84.148% |
| Barinthus Biotherapeutics plc | -83.91 Million USD | 38.04% |
| Madrigal Pharmaceuticals, Inc. | -380.49 Million USD | 86.335% |
| MiMedx Group, Inc. | 37.11 Million USD | 240.082% |
| MEI Pharma, Inc. | 14.54 Million USD | 457.537% |
| Novavax, Inc. | -566.51 Million USD | 90.822% |
| NextCure, Inc. | -67.63 Million USD | 23.129% |
| Ocuphire Pharma, Inc. | -10.56 Million USD | -392.218% |
| Onconetix, Inc. | -36.03 Million USD | -44.286% |
| Oncternal Therapeutics, Inc. | -41.71 Million USD | -24.642% |
| Opthea Limited | -191.84 Million USD | 72.898% |
| Psyence Biomedical Ltd. | -2.75 Million USD | -1789.401% |
| Vaxcyte, Inc. | -468.04 Million USD | 88.891% |
| PDS Biotechnology Corporation | -43.04 Million USD | -20.787% |
| Precigen, Inc. | -88.92 Million USD | 41.53% |
| Pharming Group N.V. | -4.87 Million USD | -965.53% |
| Phathom Pharmaceuticals, Inc. | -167.31 Million USD | 68.925% |
| Pieris Pharmaceuticals, Inc. | -29.75 Million USD | -74.731% |
| PureTech Health plc | -146.19 Million USD | 64.437% |
| Pyxis Oncology, Inc. | -82.19 Million USD | 36.745% |
| Rigel Pharmaceuticals, Inc. | -20.49 Million USD | -153.736% |
| Avidity Biosciences, Inc. | -235.59 Million USD | 77.931% |
| TransCode Therapeutics, Inc. | -19.41 Million USD | -167.75% |
| Reviva Pharmaceuticals Holdings, Inc. | -24.3 Million USD | -113.905% |
| Reviva Pharmaceuticals Holdings, Inc. | -24.3 Million USD | -113.905% |
| Seer, Inc. | -103.46 Million USD | 49.747% |
| Sangamo Therapeutics, Inc. | -274 Million USD | 81.025% |
| Sol-Gel Technologies Ltd. | -29.3 Million USD | -77.42% |
| Acelyrin, Inc. | -422.06 Million USD | 87.681% |
| Salarius Pharmaceuticals, Inc. | -12.89 Thousand USD | -403104.668% |
| SELLAS Life Sciences Group, Inc. | -37.86 Million USD | -37.297% |
| Sensei Biotherapeutics, Inc. | -37.06 Million USD | -40.279% |
| Senti Biosciences, Inc. | -92.72 Million USD | 43.929% |
| Clearside Biomedical, Inc. | -24.84 Million USD | -109.278% |
| Stoke Therapeutics, Inc. | -114.77 Million USD | 54.699% |
| Alaunos Therapeutics, Inc. | -34.26 Million USD | -51.729% |
| Telomir Pharmaceuticals, Inc. Common Stock | -3.94 Million USD | -1218.934% |
| Entrada Therapeutics, Inc. | -3.16 Million USD | -1544.307% |
| VistaGen Therapeutics, Inc. | -33.02 Million USD | -57.454% |
| VYNE Therapeutics Inc. | -29.25 Million USD | -77.705% |
| Windtree Therapeutics, Inc. | -17.53 Million USD | -196.442% |
| Wave Life Sciences Ltd. | -67.99 Million USD | 23.535% |
| Xeris Biopharma Holdings, Inc. | -44.01 Million USD | -18.139% |
| C4 Therapeutics, Inc. | -139.03 Million USD | 62.603% |
| ChromaDex Corporation | -5.59 Million USD | -828.612% |
| Sorrento Therapeutics, Inc. | -504.31 Million USD | 89.69% |
| TRACON Pharmaceuticals, Inc. | -6.89 Million USD | -653.74% |
| Viracta Therapeutics, Inc. | -50.69 Million USD | -2.564% |
| Caribou Biosciences, Inc. | -116.05 Million USD | 55.201% |
| CRISPR Therapeutics AG | -222.53 Million USD | 76.636% |
| Precision BioSciences, Inc. | -43.73 Million USD | -18.879% |
| Fate Therapeutics, Inc. | -190.51 Million USD | 72.709% |
| Innoviva, Inc. | 176.7 Million USD | 129.423% |
| Jaguar Health, Inc. | -34.29 Million USD | -51.623% |
| Summit Therapeutics Inc. | -89.73 Million USD | 42.06% |
| Verrica Pharmaceuticals Inc. | -65.75 Million USD | 20.934% |
| Aadi Bioscience, Inc. | -71.93 Million USD | 27.72% |
| ESSA Pharma Inc. | -32.13 Million USD | -61.8% |
| GlycoMimetics, Inc. | -39.27 Million USD | -32.381% |
| GT Biopharma, Inc. | -13.57 Million USD | -282.977% |
| Inhibrx Biosciences, Inc. | -219.22 Million USD | 76.283% |
| Akebia Therapeutics, Inc. | -46.25 Million USD | -12.403% |
| Catalyst Pharmaceuticals, Inc. | 86.81 Million USD | 159.891% |
| Orchestra BioMed Holdings, Inc. | -51.5 Million USD | -0.946% |
| Alzamend Neuro, Inc. | -9.93 Million USD | -423.192% |
| Rocket Pharmaceuticals, Inc. | -259.65 Million USD | 79.976% |
| Aptose Biosciences Inc. | -52.35 Million USD | 0.693% |
| ZyVersa Therapeutics, Inc. | -14.42 Million USD | -260.542% |
| Soligenix, Inc. | -7.69 Million USD | -575.414% |
| Century Therapeutics, Inc. | -146.54 Million USD | 64.521% |
| Kura Oncology, Inc. | -165.8 Million USD | 68.642% |
| TScan Therapeutics, Inc. | -93.45 Million USD | 44.368% |
| Intensity Therapeutics, Inc. | -8.31 Million USD | -524.991% |
| Ocean Biomedical, Inc. | -2.48 Million USD | -1995.107% |
| CytomX Therapeutics, Inc. | -6.48 Million USD | -701.866% |
| Autolus Therapeutics plc | -195.02 Million USD | 73.341% |
| Mineralys Therapeutics, Inc. | -84.65 Million USD | 38.584% |
| EyePoint Pharmaceuticals, Inc. | -73.66 Million USD | 29.417% |
| Eterna Therapeutics Inc. | -21.13 Million USD | -146.004% |
| Adaptive Biotechnologies Corporation | -227.03 Million USD | 77.099% |
| GRI Bio, Inc. | -11.38 Million USD | -356.6% |
| Xenetic Biosciences, Inc. | -4.51 Million USD | -1051.379% |
| Tenaya Therapeutics, Inc. | -131.19 Million USD | 60.369% |
| IGM Biosciences, Inc. | -263.46 Million USD | 80.265% |
| INmune Bio, Inc. | -29.74 Million USD | -74.819% |
| Heron Therapeutics, Inc. | -110.61 Million USD | 52.996% |
| SAB Biotherapeutics, Inc. | -38.07 Million USD | -36.553% |
| Pasithea Therapeutics Corp. | -15.97 Million USD | -225.376% |
| Entero Therapeutics, Inc. | -15.77 Million USD | -229.678% |
| Milestone Pharmaceuticals Inc. | -61.09 Million USD | 14.902% |
| X4 Pharmaceuticals, Inc. | -107.52 Million USD | 51.644% |
| Atara Biotherapeutics, Inc. | -276 Million USD | 81.162% |
| Coherus BioSciences, Inc. | -203.19 Million USD | 74.413% |
| Verastem, Inc. | -92.08 Million USD | 43.537% |
| Abeona Therapeutics Inc. | -47.13 Million USD | -10.307% |
| Pliant Therapeutics, Inc. | -184.14 Million USD | 71.765% |
| Tonix Pharmaceuticals Holding Corp. | -118.38 Million USD | 56.08% |
| Histogen Inc. | -10.64 Million USD | -388.518% |
| Aprea Therapeutics, Inc. | -15.47 Million USD | -236.047% |
| Surrozen, Inc. | -45.78 Million USD | -13.571% |
| Organovo Holdings, Inc. | -15.08 Million USD | -244.644% |
| Lixte Biotechnology Holdings, Inc. | -5.09 Million USD | -921.426% |
| Ovid Therapeutics Inc. | -59.28 Million USD | 12.295% |
| Panbela Therapeutics, Inc. | -51.29 Million USD | -1.363% |
| CASI Pharmaceuticals, Inc. | -25.28 Million USD | -105.669% |
| Cadrenal Therapeutics, Inc. Common Stock | -7.63 Million USD | -581.175% |
| Centessa Pharmaceuticals plc | -171.28 Million USD | 69.645% |
| Hepion Pharmaceuticals, Inc. | -48.44 Million USD | -7.317% |
| Arcturus Therapeutics Holdings Inc. | -78.2 Million USD | 33.517% |
| BioRestorative Therapies, Inc. | -15.22 Million USD | -241.592% |
| Apollomics, Inc. | -54.83 Million USD | 5.181% |
| Amarin Corporation plc | -67.58 Million USD | 23.074% |
| Mesoblast Limited | -58.79 Million USD | 11.568% |
| Turnstone Biologics Corp. | -59.03 Million USD | 11.924% |
| Kymera Therapeutics, Inc. | -165.53 Million USD | 68.59% |
| Synaptogenix, Inc. | -8.31 Million USD | -525.378% |
| Tiziana Life Sciences Ltd | -14.58 Million USD | -256.458% |
| Aurinia Pharmaceuticals Inc. | -91.69 Million USD | 43.295% |
| BriaCell Therapeutics Corp. | -4.79 Million USD | -985.117% |
| Monopar Therapeutics Inc. | -8.83 Million USD | -488.74% |
| Exelixis, Inc. | 170.88 Million USD | 130.426% |
| Better Therapeutics, Inc. | -38.26 Million USD | -35.887% |
| Nurix Therapeutics, Inc. | -155.06 Million USD | 66.47% |
| Apellis Pharmaceuticals, Inc. | -517.12 Million USD | 89.946% |
| NLS Pharmaceutics AG | -11.8 Million USD | -340.355% |
| Dermata Therapeutics, Inc. | -8.04 Million USD | -546.526% |
| Aridis Pharmaceuticals, Inc. | -29.99 Million USD | -73.35% |
| Gritstone bio, Inc. | -154.63 Million USD | 66.377% |
| Jasper Therapeutics, Inc. | -68.86 Million USD | 24.496% |
| TNF Pharmaceuticals, Inc. | -17.12 Million USD | -203.643% |
| Avid Bioservices, Inc. | -18.67 Million USD | -178.365% |
| Insmed Incorporated | -709.62 Million USD | 92.673% |
| Virpax Pharmaceuticals, Inc. | -15.68 Million USD | -231.381% |
| MediWound Ltd. | -15.29 Million USD | -240.046% |
| OmniAb, Inc. | -69.41 Million USD | 25.103% |
| Alector, Inc. | -151.74 Million USD | 65.735% |
| Seres Therapeutics, Inc. | -107.98 Million USD | 51.851% |
| Checkpoint Therapeutics, Inc. | -52.14 Million USD | 0.297% |
| Zai Lab Limited | -366.57 Million USD | 85.816% |
| Revance Therapeutics, Inc. | -316.77 Million USD | 83.587% |
| Aura Biosciences, Inc. | -84.99 Million USD | 38.825% |
| Lyell Immunopharma, Inc. | -245.49 Million USD | 78.822% |
| Immunic, Inc. | -99.22 Million USD | 47.6% |
| Tarsus Pharmaceuticals, Inc. | -143.15 Million USD | 63.681% |
| Veracyte, Inc. | -85.79 Million USD | 39.399% |
| InMed Pharmaceuticals Inc. | - USD | Infinity% |
| FibroGen, Inc. | -281.81 Million USD | 81.551% |
| SeaStar Medical Holding Corporation | -14.21 Million USD | -265.89% |
| Adial Pharmaceuticals, Inc. | -6.88 Million USD | -654.84% |
| Sonnet BioTherapeutics Holdings, Inc. | -18.79 Million USD | -176.667% |
| Jazz Pharmaceuticals plc | 578.58 Million USD | 108.986% |
| Cyclacel Pharmaceuticals, Inc. | -25.45 Million USD | -104.271% |
| Amylyx Pharmaceuticals, Inc. | 38.8 Million USD | 233.996% |
| TG Therapeutics, Inc. | 20.63 Million USD | 351.99% |
| Galecto, Inc. | -39.9 Million USD | -30.292% |
| Calithera Biosciences, Inc. | -42.07 Million USD | -23.575% |
| Fortrea Holdings Inc. | 63.1 Million USD | 182.398% |
| KalVista Pharmaceuticals, Inc. | -140.44 Million USD | 62.98% |
| Aptevo Therapeutics Inc. | -28.87 Million USD | -80.044% |
| XBiotech Inc. | -37.51 Million USD | -38.611% |
| Jasper Therapeutics, Inc. | -68.86 Million USD | 24.496% |
| Lyra Therapeutics, Inc. | -67.12 Million USD | 22.537% |
| Foghorn Therapeutics Inc. | -107.9 Million USD | 51.816% |
| Y-mAbs Therapeutics, Inc. | -25.67 Million USD | -102.528% |
| Theravance Biopharma, Inc. | -53.29 Million USD | 2.438% |
| Ultragenyx Pharmaceutical Inc. | -569.2 Million USD | 90.866% |
| Metagenomi, Inc. Common Stock | -78.49 Million USD | 33.76% |
| Vaxxinity, Inc. | -58.28 Million USD | 10.795% |
| BioCryst Pharmaceuticals, Inc. | -103.7 Million USD | 49.866% |
| Gain Therapeutics, Inc. | -22.25 Million USD | -133.644% |
| Cartesian Therapeutics, Inc. | -86.41 Million USD | 39.834% |
| NexImmune, Inc. | -29.19 Million USD | -78.104% |
| Creative Medical Technology Holdings, Inc. | -5.62 Million USD | -825.121% |
| Marker Therapeutics, Inc. | -14.58 Million USD | -256.571% |
| Regeneron Pharmaceuticals, Inc. | 4.04 Billion USD | 101.285% |
| Chemomab Therapeutics Ltd. | -25.45 Million USD | -104.222% |
| Scopus BioPharma Inc. | -11.71 Million USD | -343.82% |
| RAPT Therapeutics, Inc. | -127.06 Million USD | 59.081% |
| Ainos, Inc. | -13.2 Million USD | -293.696% |
| Pluri Inc. | -22.15 Million USD | -134.647% |
| Prothena Corporation plc | -191.03 Million USD | 72.784% |
| Adaptimmune Therapeutics plc | -138.03 Million USD | 62.334% |
| Celularity Inc. | -192.28 Million USD | 72.961% |
| Rallybio Corporation | -78.93 Million USD | 34.129% |
| Cue Biopharma, Inc. | -52.14 Million USD | 0.299% |
| MeiraGTx Holdings plc | -137.06 Million USD | 62.066% |
| Omeros Corporation | -164.53 Million USD | 68.399% |
| Humacyte, Inc. | -100.04 Million USD | 48.031% |
| Immunocore Holdings plc | -59.64 Million USD | 12.835% |
| Cocrystal Pharma, Inc. | -18.55 Million USD | -180.15% |
| Cidara Therapeutics, Inc. | -24.48 Million USD | -112.364% |
| Blueprint Medicines Corporation | -486.27 Million USD | 89.308% |
| CalciMedica, Inc. | -21.87 Million USD | -137.682% |
| Cabaletta Bio, Inc. | -74.66 Million USD | 30.36% |
| Marinus Pharmaceuticals, Inc. | -131.48 Million USD | 60.457% |
| Scholar Rock Holding Corporation | -171.29 Million USD | 69.647% |
| Sana Biotechnology, Inc. | -326.9 Million USD | 84.095% |
| Pulmatrix, Inc. | -14.74 Million USD | -252.734% |
| Elicio Therapeutics, Inc. | -35.74 Million USD | -45.455% |
| Vigil Neuroscience, Inc. | -88.86 Million USD | 41.493% |
| Intellia Therapeutics, Inc. | -515.29 Million USD | 89.91% |
| Adlai Nortye Ltd. American Depositary Shares | -67.55 Million USD | 23.031% |
| Cytokinetics, Incorporated | -496.2 Million USD | 89.522% |
| Eloxx Pharmaceuticals, Inc. | -34.41 Million USD | -51.059% |
| Nutriband Inc. | -4.87 Million USD | -967.196% |
| Protara Therapeutics, Inc. | -43.61 Million USD | -19.214% |
| Vor Biopharma Inc. | -126.03 Million USD | 58.748% |
| Roivant Sciences Ltd. | 4.24 Billion USD | 101.226% |
| Evogene Ltd. | -26.39 Million USD | -97.01% |
| ProKidney Corp. | -151.52 Million USD | 65.686% |
| Applied Therapeutics, Inc. | -64.53 Million USD | 19.434% |
| Hoth Therapeutics, Inc. | -7.69 Million USD | -575.915% |
| BridgeBio Pharma, Inc. | -607.37 Million USD | 91.44% |
| CorMedix Inc. | -48.95 Million USD | -6.2% |
| BioLineRx Ltd. | -49.69 Million USD | -4.626% |
| Tango Therapeutics, Inc. | -114.17 Million USD | 54.461% |
| Galectin Therapeutics Inc. | -38.07 Million USD | -36.565% |
| Atai Life Sciences N.V. | -125.47 Million USD | 58.562% |
| Renovaro Biosciences Inc. | -81.63 Million USD | 36.314% |
| Aerovate Therapeutics, Inc. | -81.4 Million USD | 36.134% |
| Zentalis Pharmaceuticals, Inc. | -248.98 Million USD | 79.118% |
| Sagimet Biosciences Inc. | -30.74 Million USD | -69.138% |
| MediciNova, Inc. | -9.9 Million USD | -425.168% |
| Praxis Precision Medicines, Inc. | -126.37 Million USD | 58.858% |
| Cardio Diagnostics Holdings, Inc. | -7.24 Million USD | -617.892% |
| GeoVax Labs, Inc. | -26.74 Million USD | -94.418% |
| Axsome Therapeutics, Inc. | -231.82 Million USD | 77.572% |
| Biomea Fusion, Inc. | -126.13 Million USD | 58.78% |
| PTC Therapeutics, Inc. | -349.4 Million USD | 85.119% |
| Mereo BioPharma Group plc | -28.41 Million USD | -82.971% |
| Cullinan Oncology, Inc. | -191.08 Million USD | 72.791% |
| Syndax Pharmaceuticals, Inc. | -229.95 Million USD | 77.39% |
| Absci Corporation | -115.51 Million USD | 54.99% |
| NRx Pharmaceuticals, Inc. | -27.58 Million USD | -88.469% |
| 4D Molecular Therapeutics, Inc. | -112.86 Million USD | 53.934% |
| Dyne Therapeutics, Inc. | -242.16 Million USD | 78.53% |
| Kiniksa Pharmaceuticals, Ltd. | -25.19 Million USD | -106.354% |
| Ventyx Biosciences, Inc. | -207.99 Million USD | 75.003% |
| Allakos Inc. | -196.05 Million USD | 73.481% |
| Imunon, Inc. | -21.03 Million USD | -147.227% |
| Fulcrum Therapeutics, Inc. | -110.66 Million USD | 53.017% |
| Corcept Therapeutics Incorporated | 107.28 Million USD | 148.464% |
| BioAtla, Inc. | -129.68 Million USD | 59.909% |
| NLS Pharmaceutics AG | -11.8 Million USD | -340.355% |
| Bio-Path Holdings, Inc. | -15.84 Million USD | -228.176% |
| Allogene Therapeutics, Inc. | -327.73 Million USD | 84.136% |
| Larimar Therapeutics, Inc. | -41.75 Million USD | -24.51% |
| XOMA Corporation | -41.84 Million USD | -24.242% |
| Kezar Life Sciences, Inc. | -105.23 Million USD | 50.594% |
| Cara Therapeutics, Inc. | -121.49 Million USD | 57.206% |
| aTyr Pharma, Inc. | -54.91 Million USD | 5.328% |
| Aligos Therapeutics, Inc. | -87.42 Million USD | 40.53% |
| Akero Therapeutics, Inc. | -172.87 Million USD | 69.924% |
| Viridian Therapeutics, Inc. | -254.45 Million USD | 79.567% |
| Eliem Therapeutics, Inc. | -21.46 Million USD | -142.211% |
| EyeGate Pharmaceuticals, Inc. | -8.21 Million USD | -533.076% |
| Akari Therapeutics, Plc | -16.8 Million USD | -209.372% |
| Tevogen Bio Holdings Inc. | -8843.03 USD | -587854.581% |
| Halozyme Therapeutics, Inc. | 337.57 Million USD | 115.402% |
| Lexaria Bioscience Corp. | -6.53 Million USD | -695.727% |
| UroGen Pharma Ltd. | -65.53 Million USD | 20.665% |
| Sutro Biopharma, Inc. | -89.27 Million USD | 41.763% |
| ZIVO Bioscience, Inc. | -7.26 Million USD | -615.86% |
| Orgenesis Inc. | -53.63 Million USD | 3.063% |
| Entera Bio Ltd. | -8.89 Million USD | -484.782% |
| GH Research PLC | -41.22 Million USD | -26.129% |
| Lisata Therapeutics, Inc. | -25.7 Million USD | -102.244% |
| Reneo Pharmaceuticals, Inc. | -83.05 Million USD | 37.398% |
| Xencor, Inc. | -138.63 Million USD | 62.498% |
| 60 Degrees Pharmaceuticals, Inc. | -5.15 Million USD | -908.675% |
| Replimune Group, Inc. | -234.77 Million USD | 77.854% |
| Coeptis Therapeutics Holdings, Inc. | -21.49 Million USD | -141.928% |
| Vanda Pharmaceuticals Inc. | -13.95 Million USD | -272.656% |
| Lexaria Bioscience Corp. | -6.53 Million USD | -695.727% |
| Portage Biotech Inc. | -18.25 Million USD | -184.846% |
| Cardio Diagnostics Holdings, Inc. | -7.24 Million USD | -617.892% |
| Olema Pharmaceuticals, Inc. | -104.96 Million USD | 50.464% |
| OncoCyte Corporation | -25.13 Million USD | -106.847% |
| Qualigen Therapeutics, Inc. | -11.3 Million USD | -359.917% |
| Processa Pharmaceuticals, Inc. | -11.45 Million USD | -353.807% |
| Purple Biotech Ltd. | 22.27 Million USD | 333.456% |
| CollPlant Biotechnologies Ltd. | -7.51 Million USD | -592.133% |
| scPharmaceuticals Inc. | -55.39 Million USD | 6.143% |
| ProMIS Neurosciences, Inc. | -18.89 Million USD | -175.129% |
| HilleVax, Inc. | -133.34 Million USD | 61.009% |
| NeuroSense Therapeutics Ltd. | -12.04 Million USD | -331.513% |
| Tharimmune, Inc. | -9.45 Million USD | -449.887% |
| Genprex, Inc. | -31.07 Million USD | -67.311% |
| Neumora Therapeutics, Inc. Common Stock | -188.19 Million USD | 72.373% |
| Atossa Therapeutics, Inc. | -31.37 Million USD | -65.704% |
| XTL Biopharmaceuticals Ltd. | -765 Thousand USD | -6696.471% |
| Virios Therapeutics, Inc. | -5.44 Million USD | -854.54% |
| OKYO Pharma Limited | -15.74 Thousand USD | -330019.945% |
| Savara Inc. | -60 Million USD | 13.355% |
| Curis, Inc. | -48.33 Million USD | -7.575% |
| Daré Bioscience, Inc. | -30.83 Million USD | -68.59% |
| Carmell Therapeutics Corporation | -5.21 Million USD | -896.554% |
| Titan Pharmaceuticals, Inc. | -7.27 Million USD | -614.484% |
| Achieve Life Sciences, Inc. | -27.25 Million USD | -90.8% |
| BeiGene, Ltd. | -1.2 Billion USD | 95.695% |
| Kiromic BioPharma, Inc. | -19.93 Million USD | -160.756% |
| Revolution Medicines, Inc. Warrant | -487.18 Million USD | 89.328% |
| Protagonist Therapeutics, Inc. | -93.65 Million USD | 44.483% |
| Erasca, Inc. | -141.52 Million USD | 63.262% |
| bluebird bio, Inc. | -244.26 Million USD | 78.714% |
| Protagenic Therapeutics, Inc. | -4.52 Million USD | -1048.516% |
| BioMarin Pharmaceutical Inc. | 194.44 Million USD | 126.74% |
| DBV Technologies S.A. | -76.43 Million USD | 31.975% |
| Protagenic Therapeutics, Inc. | -4.52 Million USD | -1048.516% |
| Moderna, Inc. | -4.23 Billion USD | 98.773% |
| Vincerx Pharma, Inc. | -42.6 Million USD | -22.024% |
| Fresh Tracks Therapeutics, Inc. | -6.36 Million USD | -717.5% |
| Molecular Templates, Inc. | -10.46 Million USD | -396.78% |
| Acrivon Therapeutics, Inc. Common Stock | -67.23 Million USD | 22.672% |
| Travere Therapeutics, Inc. | -376.74 Million USD | 86.199% |
| Monte Rosa Therapeutics, Inc. | -143.31 Million USD | 63.72% |
| Celldex Therapeutics, Inc. | -154.54 Million USD | 66.357% |
| Cogent Biosciences, Inc. | -208.13 Million USD | 75.019% |
| MacroGenics, Inc. | -168.24 Million USD | 69.097% |
| RenovoRx, Inc. | -11.39 Million USD | -356.239% |
| Adicet Bio, Inc. | -152.03 Million USD | 65.803% |
| Prime Medicine, Inc. | -191.29 Million USD | 72.82% |
| Aditxt, Inc. | -26.06 Million USD | -99.494% |
| Adagene Inc. | -23.71 Million USD | -119.196% |
| Estrella Immunopharma, Inc. | -7.31 Million USD | -611.249% |
| Quantum-Si incorporated | -111.17 Million USD | 53.232% |
| Maravai LifeSciences Holdings, Inc. | -31.64 Million USD | -64.285% |
| Acurx Pharmaceuticals, Inc. | -14.57 Million USD | -256.66% |
| Voyager Therapeutics, Inc. | 122.01 Million USD | 142.612% |
| SciSparc Ltd. | -5.77 Million USD | -800.624% |
| Vericel Corporation | -6.46 Million USD | -704.347% |
| Revelation Biosciences, Inc. | -8.65 Million USD | -500.612% |
| Minerva Neurosciences, Inc. | -23.11 Million USD | -124.887% |
| Generation Bio Co. | -138.56 Million USD | 62.477% |
| Astria Therapeutics, Inc. | -83.03 Million USD | 37.38% |
| Black Diamond Therapeutics, Inc. | -86.46 Million USD | 39.865% |
| Arcutis Biotherapeutics, Inc. | -241.1 Million USD | 78.435% |
| Invivyd, Inc. | -207.78 Million USD | 74.977% |
| Relay Therapeutics, Inc. | -373 Million USD | 86.061% |
| Quoin Pharmaceuticals, Ltd. | -9.37 Million USD | -454.385% |
| Spero Therapeutics, Inc. | 21.48 Million USD | 342.042% |
| Artelo Biosciences, Inc. | -10.28 Million USD | -405.424% |
| 2seventy bio, Inc. | -216.7 Million USD | 76.007% |
| ADMA Biologics, Inc. | 21.63 Million USD | 340.352% |
| Clene Inc. | -40.54 Million USD | -28.251% |
| Capricor Therapeutics, Inc. | -24.07 Million USD | -115.937% |
| Boundless Bio, Inc. Common Stock | -54.79 Million USD | 5.115% |
| GeoVax Labs, Inc. | -26.74 Million USD | -94.418% |
| Recursion Pharmaceuticals, Inc. | -350.06 Million USD | 85.147% |
| Citius Pharmaceuticals, Inc. | -36.73 Million USD | -41.547% |
| Contineum Therapeutics, Inc. Class A Common Stock | 16.07 Million USD | 423.4% |
| Relmada Therapeutics, Inc. | -103.7 Million USD | 49.863% |
| Finch Therapeutics Group, Inc. | -34 Million USD | -52.912% |
| ALX Oncology Holdings Inc. | -170.27 Million USD | 69.466% |
| Vir Biotechnology, Inc. | -684.3 Million USD | 92.402% |
| Evaxion Biotech A/S | -22.19 Million USD | -134.234% |
| Ocular Therapeutix, Inc. | -82.38 Million USD | 36.888% |
| Verve Therapeutics, Inc. | -223.12 Million USD | 76.698% |
| Trevena, Inc. | -35.28 Million USD | -47.339% |
| Surrozen, Inc. | -45.78 Million USD | -13.571% |
| Tyra Biosciences, Inc. | -79.94 Million USD | 34.964% |
| Cingulate Inc. | -22.75 Million USD | -128.448% |
| Galmed Pharmaceuticals Ltd. | 7.49 Million USD | 793.98% |
| Unity Biotechnology, Inc. | -44.66 Million USD | -16.401% |
| Tenax Therapeutics, Inc. | -8.23 Million USD | -531.447% |
| Terns Pharmaceuticals, Inc. | -102.55 Million USD | 49.304% |
| ACADIA Pharmaceuticals Inc. | -73.37 Million USD | 29.145% |
| Connect Biopharma Holdings Limited | -62.07 Million USD | 16.24% |
| Clearmind Medicine Inc. | -8.74 Million USD | -494.794% |
| Kronos Bio, Inc. | -121.83 Million USD | 57.323% |
| Bolt Biotherapeutics, Inc. | -76.19 Million USD | 31.764% |
| CERo Therapeutics Holdings, Inc. | -2.93 Million USD | -1672.699% |
| Viking Therapeutics, Inc. | -100.82 Million USD | 48.433% |
| Statera Biopharma, Inc. | -98.34 Million USD | 47.131% |
| ImmunityBio, Inc. | -362.25 Million USD | 85.647% |
| Korro Bio, Inc. | -84.53 Million USD | 38.495% |
| Kineta, Inc. | -15.72 Million USD | -230.681% |
| BioVie Inc. | -32.17 Million USD | -61.571% |
| Codexis, Inc. | -68.06 Million USD | 23.617% |
| Celularity Inc. | -192.28 Million USD | 72.961% |
| Crinetics Pharmaceuticals, Inc. | -222.6 Million USD | 76.644% |
| Celcuity Inc. | -66.23 Million USD | 21.497% |
| Virax Biolabs Group Limited | -6.49 Million USD | -700.327% |
| Cibus, Inc. | -318.88 Million USD | 83.695% |
| Eledon Pharmaceuticals, Inc. | -43 Million USD | -20.914% |
| eFFECTOR Therapeutics, Inc. | -33.84 Million USD | -53.625% |
| IN8bio, Inc. | -30.33 Million USD | -71.385% |
| Kodiak Sciences Inc. | -277.32 Million USD | 81.252% |
| Annexon, Inc. | -143.72 Million USD | 63.824% |
| Adverum Biotechnologies, Inc. | -123.79 Million USD | 57.999% |
| Assembly Biosciences, Inc. | -64.64 Million USD | 19.573% |
| Avalo Therapeutics, Inc. | -23.44 Million USD | -121.775% |
| Ionis Pharmaceuticals, Inc. | -353.73 Million USD | 85.302% |
| Eyenovia, Inc. | -25.4 Million USD | -104.645% |
| Puma Biotechnology, Inc. | 32.64 Million USD | 259.292% |
| Conduit Pharmaceuticals Inc. | -5.56 Million USD | -834.79% |
| Xilio Therapeutics, Inc. | -79.13 Million USD | 34.297% |
| Arcellx, Inc. | -89.88 Million USD | 42.153% |
| Cardiff Oncology, Inc. | -45.41 Million USD | -14.492% |
| Enanta Pharmaceuticals, Inc. | -137.2 Million USD | 62.106% |
| Regulus Therapeutics Inc. | -31.1 Million USD | -67.132% |
| Moolec Science SA | -6.65 Million USD | -681.403% |
| Acumen Pharmaceuticals, Inc. | -61.13 Million USD | 14.958% |
| Geron Corporation | -193.94 Million USD | 73.192% |
| LAVA Therapeutics N.V. | -43.25 Million USD | -20.207% |
| Royalty Pharma plc | 1.49 Billion USD | 103.484% |
| Atea Pharmaceuticals, Inc. | -164.16 Million USD | 68.328% |
| Greenwich LifeSciences, Inc. | -9.32 Million USD | -457.394% |
| TFF Pharmaceuticals, Inc. | -21.89 Million USD | -137.469% |
| Mersana Therapeutics, Inc. | -170.95 Million USD | 69.587% |
| Humacyte, Inc. | -100.04 Million USD | 48.031% |
| Structure Therapeutics Inc. | -102.77 Million USD | 49.411% |
| 89bio, Inc. | -151.2 Million USD | 65.614% |
| PMV Pharmaceuticals, Inc. | -80.13 Million USD | 35.116% |
| Avenue Therapeutics, Inc. | -14.54 Million USD | -257.586% |
| Genelux Corporation | -24.16 Million USD | -115.158% |
| Trevi Therapeutics, Inc. | -33.92 Million USD | -53.268% |
| Lexicon Pharmaceuticals, Inc. | -171.75 Million USD | 69.728% |
| Notable Labs, Ltd. | -14.65 Million USD | -254.732% |
| Liquidia Corporation | -73.38 Million USD | 29.149% |
| Mustang Bio, Inc. | -50.72 Million USD | -2.498% |
| Immunovant, Inc. | -282.7 Million USD | 81.609% |
| Quantum-Si incorporated | -111.17 Million USD | 53.232% |
| Arbutus Biopharma Corporation | -78.1 Million USD | 33.43% |
| DiaMedica Therapeutics Inc. | -21.26 Million USD | -144.477% |
| Vera Therapeutics, Inc. | -102.01 Million USD | 49.032% |
| Acasti Pharma Inc. | -11.31 Million USD | -359.627% |
| MiNK Therapeutics, Inc. | -22.92 Million USD | -126.835% |
| Pasithea Therapeutics Corp. | -15.97 Million USD | -225.376% |
| Xenon Pharmaceuticals Inc. | -214.05 Million USD | 75.71% |
| Elevai Labs, Inc. Common Stock | -3.66 Million USD | -1317.061% |
| NeuroBo Pharmaceuticals, Inc. | -15.88 Million USD | -227.288% |
| Tempest Therapeutics, Inc. | -29.15 Million USD | -78.321% |
| Soleno Therapeutics, Inc. | -41.38 Million USD | -25.636% |
| PepGen Inc. | -84.76 Million USD | 38.663% |
| Moleculin Biotech, Inc. | -29.63 Million USD | -75.468% |
| United Therapeutics Corporation | 1.18 Billion USD | 104.388% |
| Nuvectis Pharma, Inc. | -22.89 Million USD | -127.073% |
| Solid Biosciences Inc. | -104.31 Million USD | 50.158% |
| BriaCell Therapeutics Corp. | -32.8 Million USD | -58.476% |
| Immuneering Corporation | -58.41 Million USD | 10.991% |
| Lixte Biotechnology Holdings, Inc. | -5.09 Million USD | -921.426% |
| Silo Pharma, Inc. | -3.85 Million USD | -1248.509% |
| Belite Bio, Inc | -31.66 Million USD | -64.182% |
| XOMA Corporation | -41.84 Million USD | -24.242% |
| ARS Pharmaceuticals, Inc. | -67.52 Million USD | 22.996% |
| Bionomics Limited | -17.89 Billion USD | 99.709% |
| Apogee Therapeutics, Inc. | -93 Million USD | 44.095% |
| Alpha Tau Medical Ltd. | 35.68 Million USD | 245.72% |
| uniQure N.V. | -282.87 Million USD | 81.62% |
| Cassava Sciences, Inc. | -105.95 Million USD | 50.93% |
| Estrella Immunopharma, Inc. | -7.31 Million USD | -611.249% |
| Poseida Therapeutics, Inc. | -129.5 Million USD | 59.852% |
| Forte Biosciences, Inc. | -32.48 Million USD | -60.047% |
| Anebulo Pharmaceuticals, Inc. | -8.3 Million USD | -525.762% |
| Enlivex Therapeutics Ltd. | -29.39 Million USD | -76.877% |
| Conduit Pharmaceuticals Inc. | -5.56 Million USD | -834.79% |
| SeaStar Medical Holding Corporation | -14.21 Million USD | -265.89% |
| FibroBiologics, Inc. Common Stock | -8.88 Million USD | -484.914% |
| Altimmune, Inc. | -95.92 Million USD | 45.801% |
| Amicus Therapeutics, Inc. | -73.49 Million USD | 29.255% |
| Alpha Tau Medical Ltd. | 35.68 Million USD | 245.72% |
| Compugen Ltd. | -12.99 Million USD | -300.192% |
| Peak Bio, Inc. | -1356.23 USD | -3833541.786% |
| Zevra Therapeutics, Inc. | -49.6 Million USD | -4.816% |
| Benitec Biopharma Inc. | -22.49 Million USD | -131.183% |
| Spyre Therapeutics, Inc. | -242.3 Million USD | 78.542% |
| NKGen Biotech, Inc. Common Stock | -29.74 Million USD | -74.79% |
| Zura Bio Limited | -62.63 Million USD | 16.994% |
| PolyPid Ltd. | -22.86 Million USD | -127.371% |
| Aileron Therapeutics, Inc. | -16.27 Million USD | -219.446% |
| NKGen Biotech, Inc. Warrants | -29.74 Million USD | -74.79% |
| Instil Bio, Inc. | -159.16 Million USD | 67.335% |
| argenx SE | -425.04 Million USD | 87.768% |
| Immunome, Inc. | -109.53 Million USD | 52.531% |
| Compass Therapeutics, Inc. | -50.36 Million USD | -3.237% |
| Verona Pharma plc | -67.83 Million USD | 23.349% |
| enGene Holdings Inc. Warrants | -26.06 Million USD | -99.513% |
| Shattuck Labs, Inc. | -91.95 Million USD | 43.459% |
| CervoMed Inc. | -7.81 Million USD | -565.477% |
| LENZ Therapeutics, Inc. | -73.11 Million USD | 28.884% |
| Plus Therapeutics, Inc. | -13.32 Million USD | -290.309% |
| Dianthus Therapeutics, Inc. | -48.17 Million USD | -7.928% |
| Moolec Science SA | -6.65 Million USD | -681.403% |
| Enveric Biosciences, Inc. | -16.44 Million USD | -216.097% |
| Inovio Pharmaceuticals, Inc. | -135.22 Million USD | 61.551% |
| AnaptysBio, Inc. | -164.41 Million USD | 68.376% |
| Design Therapeutics, Inc. | -78.19 Million USD | 33.504% |
| Leap Therapeutics, Inc. | -87.04 Million USD | 40.266% |
| NeurAxis, Inc. | -6.66 Million USD | -680.149% |
| Seelos Therapeutics, Inc. | -40.49 Million USD | -28.381% |
| Lumos Pharma, Inc. | -36.61 Million USD | -42.003% |
| Achilles Therapeutics plc | -75.25 Million USD | 30.911% |
| enGene Holdings Inc. Common Stock | -26.06 Million USD | -99.513% |
| 180 Life Sciences Corp. | -13.47 Million USD | -285.776% |
| Opiant Pharmaceuticals, Inc. | 5.15 Million USD | 1108.337% |
| CERo Therapeutics Holdings, Inc. | -2.93 Million USD | -1672.699% |
| Nutriband Inc. | -4.87 Million USD | -967.196% |
| ORIC Pharmaceuticals, Inc. | -110.78 Million USD | 53.066% |
| CG Oncology, Inc. Common stock | -55.44 Million USD | 6.233% |
| Fractyl Health, Inc. Common Stock | -50.83 Million USD | -2.276% |
| Rani Therapeutics Holdings, Inc. | -66.09 Million USD | 21.341% |
| MoonLake Immunotherapeutics | -54.12 Million USD | 3.936% |
| Palisade Bio, Inc. | -13.07 Million USD | -297.804% |
| Tourmaline Bio, Inc. | -45.4 Million USD | -14.499% |
| Beam Therapeutics Inc. | -176.48 Million USD | 70.54% |
| Neurogene Inc. | -55.58 Million USD | 6.459% |
| Mirum Pharmaceuticals, Inc. | -109.15 Million USD | 52.367% |
| AEON Biopharma, Inc. | -48.42 Million USD | -7.359% |
| CARGO Therapeutics, Inc. Common Stock | -96.71 Million USD | 46.238% |
| Sesen Bio, Inc. | -25.9 Million USD | -100.675% |
| Enliven Therapeutics, Inc. | -83.52 Million USD | 37.755% |
| Kiora Pharmaceuticals, Inc. | -12.58 Million USD | -313.072% |
| Iovance Biotherapeutics, Inc. | -460.55 Million USD | 88.711% |
| Taysha Gene Therapies, Inc. | -72.43 Million USD | 28.225% |
| Athira Pharma, Inc. | -125.46 Million USD | 58.56% |
| Vaccinex, Inc. | -22.88 Million USD | -127.192% |
| HCW Biologics Inc. | -25.71 Million USD | -102.172% |
| XOMA Corporation | -41.84 Million USD | -24.242% |
| Nektar Therapeutics | -137.42 Million USD | 62.166% |
| Arvinas, Inc. | -401.5 Million USD | 87.05% |
| Tevogen Bio Holdings Inc. | -8843.03 USD | -587854.581% |
| Merus N.V. | -156.54 Million USD | 66.788% |
| Omega Therapeutics, Inc. | -100.26 Million USD | 48.142% |
| Quince Therapeutics, Inc. | -34.62 Million USD | -50.182% |
| Rezolute, Inc. | -70.42 Million USD | 26.17% |
| Clene Inc. | -40.54 Million USD | -28.251% |
| Indaptus Therapeutics, Inc. | -16.37 Million USD | -217.447% |
| BeyondSpring Inc. | -23.11 Million USD | -124.942% |
| Synlogic, Inc. | -55.16 Million USD | 5.743% |
| Allarity Therapeutics, Inc. | -17.92 Million USD | -189.994% |
| Phio Pharmaceuticals Corp. | -10.82 Million USD | -380.349% |
| Peak Bio, Inc. | -1356.23 USD | -3833541.786% |
| Werewolf Therapeutics, Inc. | -40.5 Million USD | -28.368% |
| Krystal Biotech, Inc. | -109.72 Million USD | 52.616% |
| Karyopharm Therapeutics Inc. | -129.53 Million USD | 59.863% |
| SpringWorks Therapeutics, Inc. | -343.01 Million USD | 84.842% |
| Lipella Pharmaceuticals Inc. | -4.74 Million USD | -995.523% |
| MannKind Corporation | 8.67 Million USD | 699.136% |
| Ikena Oncology, Inc. | -75.41 Million USD | 31.059% |
| Cyclerion Therapeutics, Inc. | -9.64 Million USD | -438.955% |
| Gyre Therapeutics, Inc. | -67.23 Million USD | 22.664% |
| Gossamer Bio, Inc. | -183.75 Million USD | 71.706% |
| CohBar, Inc. | -12.38 Million USD | -319.694% |
| Cognition Therapeutics, Inc. | -50.72 Million USD | -2.502% |
| NRx Pharmaceuticals, Inc. | -27.58 Million USD | -88.469% |
| Legend Biotech Corporation | -439.48 Million USD | 88.17% |
| Mural Oncology plc | -194.63 Million USD | 73.287% |
| Biora Therapeutics, Inc. | -67.14 Million USD | 22.564% |
| PaxMedica, Inc. Common Stock | -16.14 Million USD | -222.032% |
| Disc Medicine, Inc. | -91.12 Million USD | 42.943% |
| Champions Oncology, Inc. | -7.35 Million USD | -606.811% |
| REGENXBIO Inc. | -268.12 Million USD | 80.609% |
| Ensysce Biosciences, Inc. | -10.71 Million USD | -385.091% |
| Anavex Life Sciences Corp. | -55.75 Million USD | 6.749% |
| Cellectar Biosciences, Inc. | -38.96 Million USD | -33.45% |
| Edgewise Therapeutics, Inc. | -114.35 Million USD | 54.534% |
| Vaxart, Inc. | -83.34 Million USD | 37.619% |
| PharmaCyte Biotech, Inc. | -8.52 Million USD | -510.246% |
| Aldeyra Therapeutics, Inc. | -42.79 Million USD | -21.496% |
| Cellectis S.A. | -106.62 Million USD | 51.238% |
| Longeveron Inc. | -21.02 Million USD | -147.244% |
| Repare Therapeutics Inc. | -116.22 Million USD | 55.265% |
| Sarepta Therapeutics, Inc. | -267.82 Million USD | 80.587% |
| Inozyme Pharma, Inc. | -75.64 Million USD | 31.267% |
| Revolution Medicines, Inc. | -487.18 Million USD | 89.328% |
| Nymox Pharmaceutical Corporation | -6.65 Million USD | -681.615% |
| Third Harmonic Bio, Inc. | -43.95 Million USD | -18.29% |
| ArriVent BioPharma, Inc. Common Stock | -74.59 Million USD | 30.295% |
| AN2 Therapeutics, Inc. | -69.63 Million USD | 25.335% |
| Anixa Biosciences, Inc. | -11.01 Million USD | -372.191% |
| Vertex Pharmaceuticals Incorporated | 4.3 Billion USD | 101.207% |
| Denali Therapeutics Inc. | -196.69 Million USD | 73.567% |
| Revelation Biosciences, Inc. | -8.65 Million USD | -500.612% |
| Veru Inc. | -93.78 Million USD | 44.56% |
| Corvus Pharmaceuticals, Inc. | -23.32 Million USD | -122.869% |
| Cingulate Inc. | -22.75 Million USD | -128.448% |
| Passage Bio, Inc. | -108.38 Million USD | 52.031% |
| Context Therapeutics Inc. | -25.07 Million USD | -107.37% |
| Exicure, Inc. | -14.99 Million USD | -246.712% |
| Day One Biopharmaceuticals, Inc. | -206.06 Million USD | 74.769% |
| Oramed Pharmaceuticals Inc. | -40.59 Million USD | -28.068% |
| Scinai Immunotherapeutics Ltd. | -9.71 Million USD | -435.076% |
| Rhythm Pharmaceuticals, Inc. | -184.35 Million USD | 71.798% |
| Nuvalent, Inc. | -149.49 Million USD | 65.22% |
| ABVC BioPharma, Inc. | -8.21 Million USD | -532.787% |
| Carisma Therapeutics, Inc. | -88.73 Million USD | 41.404% |
| Unicycive Therapeutics, Inc. | -20.77 Million USD | -150.279% |
| OmniAb, Inc. | -69.41 Million USD | 25.103% |
| Anew Medical, Inc. | -1.3 Million USD | -3896.879% |
| Fennec Pharmaceuticals Inc. | -12.77 Million USD | -307.118% |
| Lipocine Inc. | -17.93 Million USD | -189.962% |
| Lexeo Therapeutics, Inc. Common Stock | -68.51 Million USD | 24.112% |
| Nautilus Biotechnology, Inc. | -76.15 Million USD | 31.725% |
| SAB Biotherapeutics, Inc. | -38.07 Million USD | -36.553% |
| G1 Therapeutics, Inc. | -39.52 Million USD | -31.538% |
| Bellerophon Therapeutics, Inc. | -22.38 Million USD | -132.278% |
| Sage Therapeutics, Inc. | -579.84 Million USD | 91.033% |
| Ocugen, Inc. | -65.53 Million USD | 20.659% |
| Mind Medicine (MindMed) Inc. | -93.86 Million USD | 44.609% |
| Q32 Bio Inc. | -92.1 Million USD | 43.548% |
| Brainstorm Cell Therapeutics Inc. | -21.43 Million USD | -142.516% |
| Alumis Inc. Common Stock | -158.17 Million USD | 67.129% |
| Equillium, Inc. | -14.52 Million USD | -258.029% |
| Kyverna Therapeutics, Inc. | -62.4 Million USD | 16.686% |
| Coya Therapeutics, Inc. | -7.9 Million USD | -557.86% |
| CNS Pharmaceuticals, Inc. | -18.86 Million USD | -175.604% |
| Galera Therapeutics, Inc. | -46.95 Million USD | -10.739% |
| Evelo Biosciences, Inc. | -108.46 Million USD | 52.065% |
| Comera Life Sciences Holdings, Inc. | -11.97 Million USD | -334.36% |
| Dominari Holdings Inc. | -21.79 Million USD | -138.544% |
| Edesa Biotech, Inc. | -9.22 Million USD | -463.747% |
| vTv Therapeutics Inc. | -25.5 Million USD | -103.878% |
| Bio-Techne Corporation | 206.68 Million USD | 125.156% |
| Agios Pharmaceuticals, Inc. | -391.48 Million USD | 86.719% |
| Harmony Biosciences Holdings, Inc. | 192.03 Million USD | 127.075% |
| Prelude Therapeutics Incorporated | -132.27 Million USD | 60.694% |
| Candel Therapeutics, Inc. | -38.39 Million USD | -35.43% |
| iTeos Therapeutics, Inc. | -151.1 Million USD | 65.591% |
| Nkarta, Inc. | -131.65 Million USD | 60.507% |
| BioCardia, Inc. | -11.64 Million USD | -346.522% |
| Iterum Therapeutics plc | -47.46 Million USD | -9.533% |