BioCryst Pharmaceuticals, Inc. (BCRX)

USD 6.8

(-7.23%)

Net Debt Summary of BioCryst Pharmaceuticals, Inc.

  • BioCryst Pharmaceuticals, Inc.'s latest annual net debt in 2023 was 736.26 Million USD , up 68.6% from previous year.
  • BioCryst Pharmaceuticals, Inc.'s latest quarterly net debt in 2024 Q2 was 770.43 Million USD , up 3.76% from previous quarter.
  • BioCryst Pharmaceuticals, Inc. reported annual net debt of 436.68 Million USD in 2022, up 391.49% from previous year.
  • BioCryst Pharmaceuticals, Inc. reported annual net debt of 88.84 Million USD in 2021, up 160.27% from previous year.
  • BioCryst Pharmaceuticals, Inc. reported quarterly net debt of 770.43 Million USD for 2024 Q2, up 3.76% from previous quarter.
  • BioCryst Pharmaceuticals, Inc. reported quarterly net debt of -83.81 Million USD for 2024 Q3, down -7.55% from previous quarter.

Annual Net Debt Chart of BioCryst Pharmaceuticals, Inc. (2023 - 1994)

Historical Annual Net Debt of BioCryst Pharmaceuticals, Inc. (2023 - 1994)

Year Net Debt Net Debt Growth
2023 736.26 Million USD 68.6%
2022 436.68 Million USD 391.49%
2021 88.84 Million USD 160.27%
2020 -147.41 Million USD -399.37%
2019 -29.51 Million USD -184.12%
2018 35.09 Million USD 690.36%
2017 4.44 Million USD -85.96%
2016 31.62 Million USD 809.67%
2015 3.47 Million USD 114.16%
2014 -24.54 Million USD -377.73%
2013 8.83 Million USD -3.0%
2012 9.1 Million USD -32.8%
2011 13.55 Million USD 199.51%
2010 -13.62 Million USD 66.88%
2009 -41.12 Million USD -84.07%
2008 -22.34 Million USD 28.29%
2007 -31.15 Million USD -605.27%
2006 -4.41 Million USD 84.85%
2005 -29.15 Million USD -229.89%
2004 -8.83 Million USD 25.98%
2003 -11.94 Million USD 13.62%
2002 -13.82 Million USD 26.72%
2001 -18.86 Million USD -123.36%
2000 -8.44 Million USD 1.79%
1999 -8.6 Million USD 30.08%
1998 -12.3 Million USD -232.43%
1997 -3.7 Million USD -12.12%
1996 -3.3 Million USD 40.0%
1995 -5.5 Million USD -205.56%
1994 -1.8 Million USD 0.0%

Peer Net Debt Comparison of BioCryst Pharmaceuticals, Inc.

Name Net Debt Net Debt Difference
AbCellera Biologics Inc. -55.94 Million USD 1416.171%
Alkermes plc -166.73 Million USD 541.568%
Agenus Inc. 274.13 Million USD -168.577%
Alnylam Pharmaceuticals, Inc. 1.86 Billion USD 60.626%
Aptorum Group Limited 1.35 Million USD -54155.051%
Ardelyx, Inc. 34.51 Million USD -2033.362%
Arrowhead Pharmaceuticals, Inc. 4.28 Million USD -17102.477%
Bicycle Therapeutics plc -481.46 Million USD 252.921%
BioXcel Therapeutics, Inc. 36.16 Million USD -1935.965%
ChromaDex Corporation -24.04 Million USD 3161.652%
Chimerix, Inc. -25.51 Million USD 2985.394%
Corbus Pharmaceuticals Holdings, Inc. 6.96 Million USD -10466.274%
Caribou Biosciences, Inc. -23.67 Million USD 3209.625%
CRISPR Therapeutics AG -150.84 Million USD 588.094%
Precision BioSciences, Inc. -85.41 Million USD 962.037%
Dyadic International, Inc. -6.37 Million USD 11643.659%
Eton Pharmaceuticals, Inc. -15.93 Million USD 4721.013%
Fortress Biotech, Inc. 7.66 Million USD -9505.558%
Lantern Pharma Inc. -21.7 Million USD 3492.418%
HOOKIPA Pharma Inc. -110.53 Million USD 766.081%
Inhibikase Therapeutics, Inc. -8.54 Million USD 8718.177%
Incyte Corporation -3.17 Billion USD 123.189%
IO Biotech, Inc. -140.69 Million USD 623.292%
Jaguar Health, Inc. 29.39 Million USD -2405.073%
Novavax, Inc. -298.29 Million USD 346.826%
Janux Therapeutics, Inc. 5.33 Million USD -13695.503%
Opthea Limited 28.15 Million USD -2514.818%
Ligand Pharmaceuticals Incorporated -16.78 Million USD 4485.407%
ContextLogic Inc. -232 Million USD 417.356%
MiMedx Group, Inc. -33.9 Million USD 2271.812%
Pyxis Oncology, Inc. 10.19 Million USD -7121.834%
TransCode Therapeutics, Inc. -2.31 Million USD 31876.324%
NextCure, Inc. -6.47 Million USD 11467.392%
Ocuphire Pharma, Inc. -50.5 Million USD 1557.924%
Oncternal Therapeutics, Inc. -6.37 Million USD 11642.029%
Outlook Therapeutics, Inc. 12.16 Million USD -5953.193%
Vaxcyte, Inc. -368.22 Million USD 299.949%
PDS Biotechnology Corporation -32.7 Million USD 2350.965%
Madrigal Pharmaceuticals, Inc. 17.27 Million USD -4161.292%
Pharming Group N.V. 109.8 Million USD -570.527%
Pieris Pharmaceuticals, Inc. -17.39 Million USD 4332.387%
Avidity Biosciences, Inc. -175.23 Million USD 520.171%
Reviva Pharmaceuticals Holdings, Inc. -18.51 Million USD 4075.549%
Reviva Pharmaceuticals Holdings, Inc. -18.51 Million USD 4075.549%
Sangamo Therapeutics, Inc. -7.1 Million USD 10469.944%
Sol-Gel Technologies Ltd. -5.86 Million USD 12664.266%
Acelyrin, Inc. -216.9 Million USD 439.445%
Salarius Pharmaceuticals, Inc. -5.61 Million USD 13223.547%
SELLAS Life Sciences Group, Inc. -1.72 Million USD 42806.845%
Summit Therapeutics Inc. 34.67 Million USD -2023.395%
Sensei Biotherapeutics, Inc. -6.8 Million USD 10922.666%
Senti Biosciences, Inc. 1.74 Million USD -42214.138%
Stoke Therapeutics, Inc. -184.6 Million USD 498.829%
Syros Pharmaceuticals, Inc. -77.45 Million USD 1050.622%
Alaunos Therapeutics, Inc. -6.06 Million USD 12245.596%
Telomir Pharmaceuticals, Inc. Common Stock 99.76 Thousand USD -737870.712%
Entrada Therapeutics, Inc. 628 Thousand USD -117139.809%
VistaGen Therapeutics, Inc. -117.04 Million USD 729.04%
Wave Life Sciences Ltd. -168.23 Million USD 537.647%
Sorrento Therapeutics, Inc. 110.87 Million USD -564.08%
TRACON Pharmaceuticals, Inc. -7.59 Million USD 9792.812%
Barinthus Biotherapeutics plc -129.11 Million USD 670.245%
Psyence Biomedical Ltd. 6.89 Million USD -10578.882%
Phathom Pharmaceuticals, Inc. -242.36 Million USD 403.786%
Immix Biopharma, Inc. -17.5 Million USD 4304.882%
Keros Therapeutics, Inc. -316.7 Million USD 332.478%
MEI Pharma, Inc. -3.7 Million USD 19972.227%
Windtree Therapeutics, Inc. 12.51 Million USD -5784.949%
Xeris Biopharma Holdings, Inc. 161.74 Million USD -355.21%
Rigel Pharmaceuticals, Inc. 27.79 Million USD -2549.106%
Fortress Biotech, Inc. 7.66 Million USD -9505.558%
Precigen, Inc. -481 Thousand USD 153169.854%
Clearside Biomedical, Inc. 14.08 Million USD -5128.791%
AlloVir, Inc. -62.69 Million USD 1274.418%
C4 Therapeutics, Inc. -55.61 Million USD 1423.886%
Fate Therapeutics, Inc. 61.66 Million USD -1093.958%
ImmuCell Corporation 10.99 Million USD -6599.075%
IDEAYA Biosciences, Inc. -154.14 Million USD 577.642%
Onconetix, Inc. 5.33 Million USD -13709.898%
PureTech Health plc -167.19 Million USD 540.358%
VYNE Therapeutics Inc. -30.46 Million USD 2517.157%
Elevation Oncology, Inc. -19.11 Million USD 3951.166%
Kintara Therapeutics, Inc. -4.9 Million USD 15098.289%
Seer, Inc. -4.24 Million USD 17464.764%
Verrica Pharmaceuticals Inc. -24.03 Million USD 3163.053%
Innoviva, Inc. 255.56 Million USD -188.096%
Aadi Bioscience, Inc. -55.86 Million USD 1417.961%
ESSA Pharma Inc. -33.62 Million USD 2289.861%
GlycoMimetics, Inc. -40.98 Million USD 1896.453%
GT Biopharma, Inc. -1.02 Million USD 72212.243%
Inhibrx Biosciences, Inc. -67.78 Million USD 1186.21%
Akebia Therapeutics, Inc. 61.25 Million USD -1101.93%
Catalyst Pharmaceuticals, Inc. -134.07 Million USD 649.128%
Longboard Pharmaceuticals, Inc. -13.85 Million USD 5413.698%
Orchestra BioMed Holdings, Inc. -28.87 Million USD 2650.104%
Alzamend Neuro, Inc. -75.33 Thousand USD 977435.599%
Rocket Pharmaceuticals, Inc. -30.86 Million USD 2485.672%
Aptose Biosciences Inc. -8.19 Million USD 9084.489%
ZyVersa Therapeutics, Inc. -3.12 Million USD 23630.258%
Soligenix, Inc. -4.95 Million USD 14969.263%
Century Therapeutics, Inc. 847 Thousand USD -86826.328%
Kura Oncology, Inc. -20.11 Million USD 3759.738%
TScan Therapeutics, Inc. -40.92 Million USD 1899.018%
Intensity Therapeutics, Inc. -8.39 Million USD 8867.159%
Ocean Biomedical, Inc. 1.82 Million USD -40316.535%
CytomX Therapeutics, Inc. -3.19 Million USD 23129.903%
Autolus Therapeutics plc -186.59 Million USD 494.571%
Mineralys Therapeutics, Inc. -49.3 Million USD 1593.319%
EyePoint Pharmaceuticals, Inc. -275.79 Million USD 366.962%
Eterna Therapeutics Inc. 34.26 Million USD -2048.553%
Adaptive Biotechnologies Corporation 164.36 Million USD -347.938%
GRI Bio, Inc. -1.79 Million USD 41140.468%
Xenetic Biosciences, Inc. -8.98 Million USD 8296.173%
Tenaya Therapeutics, Inc. -33.25 Million USD 2313.868%
IGM Biosciences, Inc. -72.6 Million USD 1114.057%
INmune Bio, Inc. -25.41 Million USD 2997.43%
Heron Therapeutics, Inc. 150.95 Million USD -387.752%
SAB Biotherapeutics, Inc. -50.65 Million USD 1553.376%
Pasithea Therapeutics Corp. -16.24 Million USD 4631.043%
Entero Therapeutics, Inc. -2.88 Million USD 25621.14%
Milestone Pharmaceuticals Inc. 38.01 Million USD -1836.778%
X4 Pharmaceuticals, Inc. -41.18 Million USD 1887.704%
Atara Biotherapeutics, Inc. 31.88 Million USD -2209.13%
Coherus BioSciences, Inc. 377.95 Million USD -94.805%
Verastem, Inc. -37.27 Million USD 2075.068%
Abeona Therapeutics Inc. -9.07 Million USD 8214.912%
Pliant Therapeutics, Inc. -51.86 Million USD 1519.664%
Tonix Pharmaceuticals Holding Corp. -15.13 Million USD 4964.658%
Histogen Inc. -7.48 Million USD 9933.925%
Aprea Therapeutics, Inc. -21.6 Million USD 3507.563%
Surrozen, Inc. -32.66 Million USD 2354.06%
Organovo Holdings, Inc. -1.5 Million USD 48956.403%
Lixte Biotechnology Holdings, Inc. -4.2 Million USD 17615.597%
Ovid Therapeutics Inc. 18.96 Million USD -3783.217%
Panbela Therapeutics, Inc. 2.61 Million USD -28044.725%
CASI Pharmaceuticals, Inc. 4.15 Million USD -17615.736%
Cadrenal Therapeutics, Inc. Common Stock -8.38 Million USD 8884.785%
Centessa Pharmaceuticals plc -43.44 Million USD 1794.825%
Hepion Pharmaceuticals, Inc. -14.57 Million USD 5150.923%
Arcturus Therapeutics Holdings Inc. -316.78 Million USD 332.415%
BioRestorative Therapies, Inc. -722.06 Thousand USD 102067.427%
Apollomics, Inc. -27.39 Million USD 2787.593%
Amarin Corporation plc -191.04 Million USD 485.399%
Mesoblast Limited 55.96 Million USD -1215.63%
Turnstone Biologics Corp. -14.58 Million USD 5148.45%
Kymera Therapeutics, Inc. -25.29 Million USD 3011.063%
Synaptogenix, Inc. -28.66 Million USD 2668.833%
Tiziana Life Sciences Ltd -936 Thousand USD 78760.897%
Aurinia Pharmaceuticals Inc. 48.73 Million USD -1410.847%
BriaCell Therapeutics Corp. -862.08 Thousand USD 85504.871%
Monopar Therapeutics Inc. -7.26 Million USD 10232.919%
Exelixis, Inc. -73.05 Million USD 1107.893%
Better Therapeutics, Inc. -860 Thousand USD 85712.326%
Nurix Therapeutics, Inc. -24.01 Million USD 3166.114%
Apellis Pharmaceuticals, Inc. -241.37 Million USD 405.035%
NLS Pharmaceutics AG 736.06 Thousand USD -99927.171%
Dermata Therapeutics, Inc. -7.43 Million USD 9998.53%
Aridis Pharmaceuticals, Inc. 1.25 Million USD -58613.397%
Gritstone bio, Inc. 39.49 Million USD -1764.437%
Jasper Therapeutics, Inc. -84.1 Million USD 975.455%
TNF Pharmaceuticals, Inc. -2.63 Million USD 28072.144%
Avid Bioservices, Inc. 169.72 Million USD -333.792%
Insmed Incorporated 721.62 Million USD -2.03%
Virpax Pharmaceuticals, Inc. -9.14 Million USD 8154.094%
MediWound Ltd. -5.32 Million USD 13934.386%
OmniAb, Inc. 9.2 Million USD -7900.283%
Alector, Inc. -35.63 Million USD 2166.016%
Seres Therapeutics, Inc. 85.97 Million USD -756.412%
Checkpoint Therapeutics, Inc. -4.92 Million USD 15040.463%
Viracta Therapeutics, Inc. 13.23 Million USD -5461.341%
Zai Lab Limited -775 Million USD 195.002%
Revance Therapeutics, Inc. 340.55 Million USD -116.196%
Aura Biosciences, Inc. -21.52 Million USD 3520.516%
Lyell Immunopharma, Inc. -82.48 Million USD 992.66%
Immunic, Inc. -45.34 Million USD 1723.877%
Tarsus Pharmaceuticals, Inc. -193.21 Million USD 481.06%
Veracyte, Inc. -203.82 Million USD 461.226%
InMed Pharmaceuticals Inc. 638.29 Million USD -15.349%
FibroGen, Inc. 56.76 Million USD -1196.996%
SeaStar Medical Holding Corporation 8.9 Million USD -8168.007%
Adial Pharmaceuticals, Inc. -2.82 Million USD 26143.32%
Sonnet BioTherapeutics Holdings, Inc. -2.07 Million USD 35662.427%
Jazz Pharmaceuticals plc 4.59 Billion USD 83.961%
Cyclacel Pharmaceuticals, Inc. -3.34 Million USD 22137.294%
Amylyx Pharmaceuticals, Inc. -165.96 Million USD 543.63%
TG Therapeutics, Inc. 17.86 Million USD -4021.968%
Galecto, Inc. -21.21 Million USD 3570.334%
Calithera Biosciences, Inc. -23.78 Million USD 3195.506%
Fortrea Holdings Inc. 1.56 Billion USD 53.086%
KalVista Pharmaceuticals, Inc. -24.47 Million USD 3108.606%
Aptevo Therapeutics Inc. -11.5 Million USD 6498.418%
XBiotech Inc. -200.02 Million USD 468.091%
Jasper Therapeutics, Inc. -84.1 Million USD 975.455%
Lyra Therapeutics, Inc. 4.52 Million USD -16160.292%
Foghorn Therapeutics Inc. -35.26 Million USD 2187.928%
Y-mAbs Therapeutics, Inc. -77.21 Million USD 1053.49%
Theravance Biopharma, Inc. 5.69 Million USD -12837.375%
Ultragenyx Pharmaceutical Inc. -170.41 Million USD 532.043%
Metagenomi, Inc. Common Stock -92.37 Million USD 897.049%
Vaxxinity, Inc. 10.13 Million USD -7166.739%
Gain Therapeutics, Inc. -10.76 Million USD 6937.822%
Cartesian Therapeutics, Inc. -65.95 Million USD 1216.299%
NexImmune, Inc. -3.13 Million USD 23595.529%
Creative Medical Technology Holdings, Inc. -3.45 Million USD 21424.522%
Marker Therapeutics, Inc. -15.11 Million USD 4972.239%
Regeneron Pharmaceuticals, Inc. -27.1 Million USD 2816.849%
Chemomab Therapeutics Ltd. -8.97 Million USD 8302.559%
Scopus BioPharma Inc. -124.57 Thousand USD 591122.276%
RAPT Therapeutics, Inc. -40.57 Million USD 1914.715%
Ainos, Inc. 4.07 Million USD -17954.904%
Pluri Inc. 22.82 Million USD -3125.135%
Prothena Corporation plc -608.34 Million USD 221.027%
Adaptimmune Therapeutics plc -118.75 Million USD 719.982%
Celularity Inc. 65.19 Million USD -1029.416%
Rallybio Corporation -24.1 Million USD 3154.792%
Cue Biopharma, Inc. -33.81 Million USD 2277.078%
MeiraGTx Holdings plc -40.3 Million USD 1926.872%
Omeros Corporation 331.17 Million USD -122.319%
Humacyte, Inc. -22.48 Million USD 3374.331%
Immunocore Holdings plc -358.59 Million USD 305.32%
Cocrystal Pharma, Inc. -24.57 Million USD 3095.996%
Cidara Therapeutics, Inc. -30.9 Million USD 2482.661%
Blueprint Medicines Corporation 702.83 Million USD -4.756%
CalciMedica, Inc. -5.53 Million USD 13414.033%
Cabaletta Bio, Inc. -188.22 Million USD 491.173%
Marinus Pharmaceuticals, Inc. -10.21 Million USD 7308.4%
Scholar Rock Holding Corporation -40.03 Million USD 1938.964%
Sana Biotechnology, Inc. -33.25 Million USD 2314.134%
Pulmatrix, Inc. -10.41 Million USD 7167.927%
Elicio Therapeutics, Inc. -5.97 Million USD 12418.32%
Vigil Neuroscience, Inc. -38.14 Million USD 2030.329%
Intellia Therapeutics, Inc. -111.4 Million USD 760.909%
Adlai Nortye Ltd. American Depositary Shares -59.94 Million USD 1328.256%
Cytokinetics, Incorporated 642.37 Million USD -14.617%
Eloxx Pharmaceuticals, Inc. -5.82 Million USD 12744.101%
Nutriband Inc. -251.65 Thousand USD 292667.264%
Protara Therapeutics, Inc. -34.11 Million USD 2257.935%
Vor Biopharma Inc. 4.3 Million USD -17022.465%
Roivant Sciences Ltd. -6.03 Billion USD 112.198%
Evogene Ltd. -19.63 Million USD 3849.954%
ProKidney Corp. -56.23 Million USD 1409.243%
Applied Therapeutics, Inc. -48.67 Million USD 1612.71%
Hoth Therapeutics, Inc. -9.23 Million USD 8070.673%
BridgeBio Pharma, Inc. 1.36 Billion USD 46.018%
CorMedix Inc. -43.05 Million USD 1810.158%
BioLineRx Ltd. 7.33 Million USD -9936.341%
Tango Therapeutics, Inc. -27.46 Million USD 2780.743%
Galectin Therapeutics Inc. 46.14 Million USD -1495.48%
Atai Life Sciences N.V. -28.55 Million USD 2678.143%
Renovaro Biosciences Inc. 2.23 Million USD -32908.582%
Aerovate Therapeutics, Inc. -22.81 Million USD 3326.972%
Zentalis Pharmaceuticals, Inc. 17.73 Million USD -4051.486%
Sagimet Biosciences Inc. -75.07 Million USD 1080.72%
MediciNova, Inc. -50.78 Million USD 1549.813%
Praxis Precision Medicines, Inc. -78.8 Million USD 1034.288%
Cardio Diagnostics Holdings, Inc. -22.49 Thousand USD 3273120.671%
GeoVax Labs, Inc. -6.45 Million USD 11510.397%
Axsome Therapeutics, Inc. -199.82 Million USD 468.463%
Biomea Fusion, Inc. -166.57 Million USD 542.016%
PTC Therapeutics, Inc. -178.97 Million USD 511.379%
Mereo BioPharma Group plc -51.46 Million USD 1530.504%
Cullinan Oncology, Inc. -94.84 Million USD 876.292%
Syndax Pharmaceuticals, Inc. -293.75 Million USD 350.636%
Absci Corporation -72.59 Million USD 1114.168%
NRx Pharmaceuticals, Inc. 4.56 Million USD -16024.967%
4D Molecular Therapeutics, Inc. -234.43 Million USD 414.057%
Dyne Therapeutics, Inc. -94.21 Million USD 881.507%
Kiniksa Pharmaceuticals, Ltd. -95.69 Million USD 869.38%
Ventyx Biosciences, Inc. -39.07 Million USD 1984.334%
Allakos Inc. -24.97 Million USD 3048.012%
Imunon, Inc. -4.21 Million USD 17572.517%
Fulcrum Therapeutics, Inc. -14.74 Million USD 5094.343%
Corcept Therapeutics Incorporated -135.4 Million USD 643.771%
BioAtla, Inc. -109.01 Million USD 775.405%
NLS Pharmaceutics AG 736.06 Thousand USD -99927.171%
Bio-Path Holdings, Inc. -939 Thousand USD 78509.585%
Allogene Therapeutics, Inc. 11.96 Million USD -6052.983%
Larimar Therapeutics, Inc. -21.2 Million USD 3572.461%
XOMA Corporation -29 Million USD 2638.848%
Kezar Life Sciences, Inc. -16.56 Million USD 4546.051%
Cara Therapeutics, Inc. -9.01 Million USD 8266.216%
aTyr Pharma, Inc. -7.44 Million USD 9984.092%
Aligos Therapeutics, Inc. -124.63 Million USD 690.733%
Akero Therapeutics, Inc. -208.16 Million USD 453.695%
Viridian Therapeutics, Inc. -81.77 Million USD 1000.312%
Eliem Therapeutics, Inc. -92.76 Million USD 893.707%
EyeGate Pharmaceuticals, Inc. -859.18 Thousand USD 85793.635%
Akari Therapeutics, Plc -3.84 Million USD 19248.661%
Tevogen Bio Holdings Inc. 1.62 Million USD -45267.585%
Halozyme Therapeutics, Inc. 1.38 Billion USD 46.681%
Lexaria Bioscience Corp. -1.18 Million USD 62068.211%
UroGen Pharma Ltd. 4.39 Million USD -16667.616%
Sutro Biopharma, Inc. 113.48 Million USD -548.801%
ZIVO Bioscience, Inc. 71.96 Thousand USD -1023031.653%
Orgenesis Inc. 21.78 Million USD -3279.848%
Entera Bio Ltd. -10.62 Million USD 7026.955%
GH Research PLC -78.07 Million USD 1043.0%
Lisata Therapeutics, Inc. -22.28 Million USD 3403.419%
Reneo Pharmaceuticals, Inc. -26.65 Million USD 2861.792%
Xencor, Inc. 29.64 Million USD -2383.693%
60 Degrees Pharmaceuticals, Inc. -1.96 Million USD 37477.476%
Replimune Group, Inc. 1.41 Million USD -52043.484%
Coeptis Therapeutics Holdings, Inc. -244.9 Thousand USD 300729.624%
Vanda Pharmaceuticals Inc. -126.41 Million USD 682.411%
Lexaria Bioscience Corp. -1.18 Million USD 62068.211%
Portage Biotech Inc. -4.98 Million USD 14881.49%
Cardio Diagnostics Holdings, Inc. -22.49 Thousand USD 3273120.671%
Olema Pharmaceuticals, Inc. -66.12 Million USD 1213.496%
OncoCyte Corporation -6.56 Million USD 11318.437%
Qualigen Therapeutics, Inc. 897.41 Thousand USD -81943.162%
Processa Pharmaceuticals, Inc. -4.55 Million USD 16261.626%
Purple Biotech Ltd. -14.13 Million USD 5307.71%
CollPlant Biotechnologies Ltd. -23.75 Million USD 3199.284%
scPharmaceuticals Inc. -6.54 Million USD 11349.29%
ProMIS Neurosciences, Inc. -16.69 Million USD 4510.848%
HilleVax, Inc. -165.48 Million USD 544.914%
NeuroSense Therapeutics Ltd. -2.53 Million USD 29109.693%
Tharimmune, Inc. -10.93 Million USD 6832.897%
Genprex, Inc. -6.73 Million USD 11027.672%
Neumora Therapeutics, Inc. Common Stock -368.8 Million USD 299.634%
Atossa Therapeutics, Inc. -88.46 Million USD 932.315%
XTL Biopharmaceuticals Ltd. -1.4 Million USD 52652.891%
Virios Therapeutics, Inc. -3.31 Million USD 22297.105%
OKYO Pharma Limited -826.84 Thousand USD 89144.903%
Savara Inc. 153 Thousand USD -481119.608%
Curis, Inc. -23.88 Million USD 3182.287%
Daré Bioscience, Inc. -5.15 Million USD 14374.5%
Carmell Therapeutics Corporation -776.01 Thousand USD 94978.172%
Titan Pharmaceuticals, Inc. -6.2 Million USD 11959.955%
Achieve Life Sciences, Inc. 1.18 Million USD -62032.152%
BeiGene, Ltd. -2.25 Billion USD 132.678%
Kiromic BioPharma, Inc. 12.33 Million USD -5867.225%
Revolution Medicines, Inc. Warrant -608.2 Million USD 221.056%
Protagonist Therapeutics, Inc. -185.58 Million USD 496.725%
Erasca, Inc. -37.21 Million USD 2078.359%
bluebird bio, Inc. 108.57 Million USD -578.142%
Protagenic Therapeutics, Inc. -1.28 Million USD 57268.259%
BioMarin Pharmaceutical Inc. 378.74 Million USD -94.395%
DBV Technologies S.A. -126.98 Million USD 679.801%
Protagenic Therapeutics, Inc. -1.28 Million USD 57268.259%
Moderna, Inc. -2.9 Billion USD 125.327%
Vincerx Pharma, Inc. -10.35 Million USD 7212.307%
Fresh Tracks Therapeutics, Inc. -10.86 Million USD 6874.623%
Molecular Templates, Inc. 707 Thousand USD -104039.463%
Acrivon Therapeutics, Inc. Common Stock -31.37 Million USD 2446.964%
Travere Therapeutics, Inc. 346.6 Million USD -112.42%
Monte Rosa Therapeutics, Inc. -82.06 Million USD 997.207%
Spruce Biosciences, Inc. -91.73 Million USD 902.645%
Celldex Therapeutics, Inc. -32.27 Million USD 2381.439%
Cogent Biosciences, Inc. -34.37 Million USD 2241.802%
MacroGenics, Inc. -66.98 Million USD 1199.151%
RenovoRx, Inc. -1.17 Million USD 62867.775%
Adicet Bio, Inc. -138.78 Million USD 630.501%
Prime Medicine, Inc. -27.94 Million USD 2735.074%
Aditxt, Inc. 18.12 Million USD -3963.08%
Adagene Inc. -87.62 Million USD 940.224%
Estrella Immunopharma, Inc. -4.16 Million USD 17775.639%
Quantum-Si incorporated -118.55 Million USD 721.023%
Maravai LifeSciences Holdings, Inc. 36 Million USD -1944.899%
Acurx Pharmaceuticals, Inc. -7.47 Million USD 9950.782%
Voyager Therapeutics, Inc. -48.5 Million USD 1617.793%
SciSparc Ltd. -2.06 Million USD 35754.528%
Vericel Corporation 1.27 Million USD -57555.912%
Revelation Biosciences, Inc. -11.99 Million USD 6239.796%
Minerva Neurosciences, Inc. 41 Million USD -1695.585%
Generation Bio Co. 31.44 Million USD -2241.217%
Astria Therapeutics, Inc. -175.36 Million USD 519.85%
Black Diamond Therapeutics, Inc. -30.92 Million USD 2480.966%
Arcutis Biotherapeutics, Inc. 116.59 Million USD -531.484%
Invivyd, Inc. -198.47 Million USD 470.96%
Relay Therapeutics, Inc. -90.27 Million USD 915.626%
Quoin Pharmaceuticals, Ltd. -2.39 Million USD 30807.328%
Spero Therapeutics, Inc. -70.79 Million USD 1140.071%
Artelo Biosciences, Inc. -6.82 Million USD 10887.78%
2seventy bio, Inc. 181.71 Million USD -305.176%
ADMA Biologics, Inc. 90.06 Million USD -717.474%
Clene Inc. 3.34 Million USD -21943.892%
Capricor Therapeutics, Inc. -9.08 Million USD 8206.243%
Boundless Bio, Inc. Common Stock -21.51 Million USD 3522.742%
GeoVax Labs, Inc. -6.45 Million USD 11510.397%
Recursion Pharmaceuticals, Inc. -344.12 Million USD 313.954%
Citius Pharmaceuticals, Inc. -25.99 Million USD 2931.827%
Contineum Therapeutics, Inc. Class A Common Stock 177.66 Million USD -314.41%
Relmada Therapeutics, Inc. -4.09 Million USD 18094.719%
Finch Therapeutics Group, Inc. 5 Million USD -14619.432%
ALX Oncology Holdings Inc. -5.2 Million USD 14234.498%
Vir Biotechnology, Inc. -130.3 Million USD 665.037%
Evaxion Biotech A/S 5.28 Million USD -13826.38%
Ocular Therapeutix, Inc. -112.56 Million USD 754.063%
Verve Therapeutics, Inc. -131.27 Million USD 660.866%
Trevena, Inc. 2.25 Million USD -32506.997%
Surrozen, Inc. -32.66 Million USD 2354.06%
Tyra Biosciences, Inc. -51.51 Million USD 1529.365%
Cingulate Inc. 3.08 Million USD -23783.935%
Galmed Pharmaceuticals Ltd. -2.93 Million USD 25168.641%
Unity Biotechnology, Inc. 7.18 Million USD -10144.414%
Tenax Therapeutics, Inc. -9.29 Million USD 8024.314%
Terns Pharmaceuticals, Inc. -79.32 Million USD 1028.187%
ACADIA Pharmaceuticals Inc. -131.45 Million USD 660.103%
Connect Biopharma Holdings Limited -105.54 Million USD 797.605%
Clearmind Medicine Inc. -3.94 Million USD 18774.456%
Kronos Bio, Inc. -36.05 Million USD 2142.12%
Bolt Biotherapeutics, Inc. 9.4 Million USD -7725.125%
CERo Therapeutics Holdings, Inc. 1.45 Million USD -50393.956%
Viking Therapeutics, Inc. -54.25 Million USD 1457.022%
Statera Biopharma, Inc. 14.41 Million USD -5007.14%
ImmunityBio, Inc. 618.22 Million USD -19.094%
Korro Bio, Inc. -132.94 Million USD 653.821%
Kineta, Inc. -4.54 Million USD 16313.741%
BioVie Inc. -17.73 Million USD 4252.106%
Codexis, Inc. -43.27 Million USD 1801.523%
Celularity Inc. 65.19 Million USD -1029.416%
Crinetics Pharmaceuticals, Inc. -3.16 Million USD 23333.386%
Celcuity Inc. 6.78 Million USD -10753.763%
Virax Biolabs Group Limited -3.36 Million USD 21980.483%
Cibus, Inc. -8.07 Million USD 9214.459%
Eledon Pharmaceuticals, Inc. -4.22 Million USD 17509.931%
eFFECTOR Therapeutics, Inc. 4.57 Million USD -16010.853%
IN8bio, Inc. -16.38 Million USD 4592.44%
Kodiak Sciences Inc. -103.87 Million USD 808.8%
Annexon, Inc. -193.75 Million USD 479.998%
Adverum Biotechnologies, Inc. 36 Thousand USD -2045083.333%
Assembly Biosciences, Inc. -17.49 Million USD 4307.475%
Avalo Therapeutics, Inc. -3.51 Million USD 21058.326%
Ionis Pharmaceuticals, Inc. 1.05 Billion USD 30.164%
Eyenovia, Inc. 1.25 Million USD -58394.068%
Puma Biotechnology, Inc. 26.9 Million USD -2636.54%
Conduit Pharmaceuticals Inc. -3.24 Million USD 22803.238%
Xilio Therapeutics, Inc. -33.24 Million USD 2314.534%
Arcellx, Inc. -296.95 Million USD 347.936%
Cardiff Oncology, Inc. -19.5 Million USD 3874.562%
Enanta Pharmaceuticals, Inc. -58.87 Million USD 1350.558%
Regulus Therapeutics Inc. -20.72 Million USD 3652.207%
Moolec Science SA 117.61 Thousand USD -625891.362%
Acumen Pharmaceuticals, Inc. -38.39 Million USD 2017.409%
Geron Corporation 14.76 Million USD -4887.914%
LAVA Therapeutics N.V. -37.91 Million USD 2041.732%
Royalty Pharma plc 5.65 Billion USD 86.988%
Atea Pharmaceuticals, Inc. -141.42 Million USD 620.62%
Greenwich LifeSciences, Inc. -6.98 Million USD 10634.001%
TFF Pharmaceuticals, Inc. -5.36 Million USD 13828.983%
Mersana Therapeutics, Inc. -140.73 Million USD 623.173%
Humacyte, Inc. -22.48 Million USD 3374.331%
Structure Therapeutics Inc. -124.33 Million USD 692.144%
89bio, Inc. -289.05 Million USD 354.717%
PMV Pharmaceuticals, Inc. -25.24 Million USD 3016.829%
Avenue Therapeutics, Inc. -1.78 Million USD 41393.662%
Genelux Corporation -6.89 Million USD 10772.068%
Trevi Therapeutics, Inc. -31.05 Million USD 2470.54%
Lexicon Pharmaceuticals, Inc. 83.59 Million USD -780.711%
Notable Labs, Ltd. -9.77 Million USD 7631.363%
Liquidia Corporation -80.17 Million USD 1018.312%
Mustang Bio, Inc. -3.73 Million USD 19807.334%
Immunovant, Inc. -635.22 Million USD 215.906%
Quantum-Si incorporated -118.55 Million USD 721.023%
Arbutus Biopharma Corporation -17.56 Million USD 4291.904%
DiaMedica Therapeutics Inc. -4.14 Million USD 17871.325%
Vera Therapeutics, Inc. 8.02 Million USD -9072.368%
Acasti Pharma Inc. -23 Million USD 3300.461%
MiNK Therapeutics, Inc. -3.36 Million USD 21965.635%
Pasithea Therapeutics Corp. -16.24 Million USD 4631.043%
Xenon Pharmaceuticals Inc. -137.74 Million USD 634.533%
Elevai Labs, Inc. Common Stock -3.11 Million USD 23725.818%
NeuroBo Pharmaceuticals, Inc. -22.23 Million USD 3411.74%
Tempest Therapeutics, Inc. -18.56 Million USD 4065.028%
Soleno Therapeutics, Inc. -169.27 Million USD 534.945%
PepGen Inc. -60.67 Million USD 1313.559%
Moleculin Biotech, Inc. -22.97 Million USD 3304.5%
United Therapeutics Corporation -507.7 Million USD 245.02%
Nuvectis Pharma, Inc. -19.12 Million USD 3949.556%
Solid Biosciences Inc. -47.75 Million USD 1641.918%
BriaCell Therapeutics Corp. -862.08 Thousand USD 85504.871%
Immuneering Corporation -54.94 Million USD 1440.058%
Lixte Biotechnology Holdings, Inc. -4.2 Million USD 17615.597%
Silo Pharma, Inc. -3.52 Million USD 20991.08%
Belite Bio, Inc -87.27 Million USD 943.655%
XOMA Corporation -29 Million USD 2638.848%
ARS Pharmaceuticals, Inc. -70.69 Million USD 1141.439%
Bionomics Limited 227 Million USD -224.332%
Apogee Therapeutics, Inc. -116.28 Million USD 733.173%
Alpha Tau Medical Ltd. -2.53 Million USD 29166.956%
uniQure N.V. -102.95 Million USD 815.162%
Cassava Sciences, Inc. -121.13 Million USD 707.801%
Estrella Immunopharma, Inc. -4.16 Million USD 17775.639%
Poseida Therapeutics, Inc. 40.95 Million USD -1697.919%
Forte Biosciences, Inc. -11.96 Million USD 6255.556%
Anebulo Pharmaceuticals, Inc. -3.09 Million USD 23895.036%
Enlivex Therapeutics Ltd. 106 Thousand USD -694490.566%
Conduit Pharmaceuticals Inc. -3.24 Million USD 22803.238%
SeaStar Medical Holding Corporation 8.9 Million USD -8168.007%
FibroBiologics, Inc. Common Stock -7.41 Million USD 10028.074%
Altimmune, Inc. -134.48 Million USD 647.463%
Amicus Therapeutics, Inc. 198.06 Million USD -271.729%
Alpha Tau Medical Ltd. -2.53 Million USD 29166.956%
Compugen Ltd. -12.9 Million USD 5805.719%
Peak Bio, Inc. 10.34 Million USD -7020.452%
Zevra Therapeutics, Inc. -283 Thousand USD 260264.664%
Benitec Biopharma Inc. -50.58 Million USD 1555.589%
Spyre Therapeutics, Inc. -104.33 Million USD 805.655%
NKGen Biotech, Inc. Common Stock 19.64 Million USD -3647.854%
Zura Bio Limited -99.8 Million USD 837.697%
PolyPid Ltd. 6.17 Million USD -11832.998%
Aileron Therapeutics, Inc. 74.12 Million USD -893.343%
NKGen Biotech, Inc. Warrants 19.64 Million USD -3647.854%
Instil Bio, Inc. 75.35 Million USD -877.024%
argenx SE -2.02 Billion USD 136.29%
Immunome, Inc. -97.02 Million USD 858.81%
Compass Therapeutics, Inc. -22.49 Million USD 3373.021%
Verona Pharma plc -220.44 Million USD 433.994%
enGene Holdings Inc. Warrants -71.74 Million USD 1126.255%
Shattuck Labs, Inc. -121.42 Million USD 706.36%
CervoMed Inc. -7.79 Million USD 9547.973%
LENZ Therapeutics, Inc. -185.49 Million USD 496.911%
Plus Therapeutics, Inc. -4.37 Million USD 16936.634%
Dianthus Therapeutics, Inc. -131.73 Million USD 658.878%
Moolec Science SA 117.61 Thousand USD -625891.362%
Enveric Biosciences, Inc. -2.28 Million USD 32279.782%
Inovio Pharmaceuticals, Inc. 15.89 Million USD -4531.076%
AnaptysBio, Inc. -18.15 Million USD 4156.338%
Design Therapeutics, Inc. -18.15 Million USD 4156.562%
Leap Therapeutics, Inc. -70.38 Million USD 1146.115%
NeurAxis, Inc. 145.7 Thousand USD -505230.13%
Seelos Therapeutics, Inc. 11.23 Million USD -6455.075%
Lumos Pharma, Inc. -28.49 Million USD 2684.024%
Achilles Therapeutics plc -126.92 Million USD 680.084%
enGene Holdings Inc. Common Stock -71.74 Million USD 1126.255%
180 Life Sciences Corp. -655.73 Thousand USD 112381.884%
Opiant Pharmaceuticals, Inc. -20.77 Million USD 3644.2%
CERo Therapeutics Holdings, Inc. 1.45 Million USD -50393.956%
Nutriband Inc. -251.65 Thousand USD 292667.264%
ORIC Pharmaceuticals, Inc. -13.17 Million USD 5690.054%
CG Oncology, Inc. Common stock -7.44 Million USD 9996.048%
Fractyl Health, Inc. Common Stock 340.19 Million USD -116.423%
Rani Therapeutics Holdings, Inc. 23.73 Million USD -3002.027%
MoonLake Immunotherapeutics -447.47 Million USD 264.539%
Palisade Bio, Inc. -12.06 Million USD 6203.507%
Tourmaline Bio, Inc. -140.31 Million USD 624.739%
Beam Therapeutics Inc. -262.72 Million USD 380.245%
Neurogene Inc. -131.95 Million USD 657.967%
Mirum Pharmaceuticals, Inc. 21.81 Million USD -3274.89%
AEON Biopharma, Inc. -4.88 Million USD 15187.418%
CARGO Therapeutics, Inc. Common Stock -377.19 Million USD 295.197%
Sesen Bio, Inc. -112.55 Million USD 754.15%
Enliven Therapeutics, Inc. -99.86 Million USD 837.298%
Kiora Pharmaceuticals, Inc. -2.34 Million USD 31459.92%
Iovance Biotherapeutics, Inc. -39.02 Million USD 1986.604%
Taysha Gene Therapies, Inc. -83.28 Million USD 984.064%
Athira Pharma, Inc. -88.99 Million USD 927.274%
Vaccinex, Inc. -1.28 Million USD 57263.509%
HCW Biologics Inc. 2.85 Million USD -25673.521%
XOMA Corporation -29 Million USD 2638.848%
Nektar Therapeutics 210.24 Million USD -250.203%
Arvinas, Inc. -313.8 Million USD 334.629%
Tevogen Bio Holdings Inc. 1.62 Million USD -45267.585%
Merus N.V. -192.88 Million USD 481.714%
Omega Therapeutics, Inc. 59.98 Million USD -1127.417%
Quince Therapeutics, Inc. -6.93 Million USD 10712.078%
Rezolute, Inc. -68.16 Million USD 1180.076%
Clene Inc. 3.34 Million USD -21943.892%
Indaptus Therapeutics, Inc. -13.18 Million USD 5683.271%
BeyondSpring Inc. -13.75 Million USD 5452.715%
Synlogic, Inc. -6.68 Million USD 11113.702%
Allarity Therapeutics, Inc. 1.13 Million USD -64826.455%
Phio Pharmaceuticals Corp. -8.45 Million USD 8808.054%
Peak Bio, Inc. 10.34 Million USD -7020.452%
Werewolf Therapeutics, Inc. -82.42 Million USD 993.31%
Krystal Biotech, Inc. -350.23 Million USD 310.221%
Karyopharm Therapeutics Inc. 124.12 Million USD -493.165%
SpringWorks Therapeutics, Inc. -168.99 Million USD 535.671%
Lipella Pharmaceuticals Inc. -3.15 Million USD 23420.634%
MannKind Corporation 143.89 Million USD -411.655%
Ikena Oncology, Inc. -109.15 Million USD 774.508%
Cyclerion Therapeutics, Inc. -7.57 Million USD 9824.818%
Gyre Therapeutics, Inc. -33.1 Million USD 2324.369%
Gossamer Bio, Inc. 180.35 Million USD -308.232%
CohBar, Inc. -5.93 Million USD 12514.422%
Cognition Therapeutics, Inc. -29.74 Million USD 2575.01%
NRx Pharmaceuticals, Inc. 4.56 Million USD -16024.967%
Legend Biotech Corporation -949.39 Million USD 177.551%
Mural Oncology plc -255.84 Million USD 387.78%
Biora Therapeutics, Inc. 32.21 Million USD -2185.476%
PaxMedica, Inc. Common Stock -4.71 Million USD 15729.844%
Disc Medicine, Inc. -358.28 Million USD 305.5%
Champions Oncology, Inc. 4.81 Million USD -15200.623%
REGENXBIO Inc. 54.76 Million USD -1244.336%
Ensysce Biosciences, Inc. -268.9 Thousand USD 273899.492%
Anavex Life Sciences Corp. -151.02 Million USD 587.516%
Cellectar Biosciences, Inc. -9.01 Million USD 8269.835%
Edgewise Therapeutics, Inc. -80.68 Million USD 1012.542%
Vaxart, Inc. -8.24 Million USD 9034.183%
PharmaCyte Biotech, Inc. -50.17 Million USD 1567.251%
Aldeyra Therapeutics, Inc. -127.16 Million USD 678.982%
Cellectis S.A. -43.85 Million USD 1778.864%
Longeveron Inc. -2.9 Million USD 25418.638%
Repare Therapeutics Inc. -107.85 Million USD 782.625%
Sarepta Therapeutics, Inc. 968.37 Million USD 23.969%
Inozyme Pharma, Inc. 12 Million USD -6033.505%
Revolution Medicines, Inc. -608.2 Million USD 221.056%
Nymox Pharmaceutical Corporation -1.23 Million USD 59959.024%
Third Harmonic Bio, Inc. -265.11 Million USD 377.714%
ArriVent BioPharma, Inc. Common Stock -150.07 Million USD 590.609%
AN2 Therapeutics, Inc. -15.64 Million USD 4805.477%
Anixa Biosciences, Inc. -740 Thousand USD 99595.405%
Vertex Pharmaceuticals Incorporated -9.56 Billion USD 107.698%
Denali Therapeutics Inc. -74.86 Million USD 1083.458%
Revelation Biosciences, Inc. -11.99 Million USD 6239.796%
Veru Inc. 4.77 Million USD -15303.154%
Corvus Pharmaceuticals, Inc. -11.24 Million USD 6646.914%
Cingulate Inc. 3.08 Million USD -23783.935%
Passage Bio, Inc. 4.58 Million USD -15958.146%
Context Therapeutics Inc. -14.44 Million USD 5195.327%
Exicure, Inc. 5.84 Million USD -12487.895%
Day One Biopharmaceuticals, Inc. -230.37 Million USD 419.593%
Oramed Pharmaceuticals Inc. -39.57 Million USD 1960.667%
Scinai Immunotherapeutics Ltd. 15.69 Million USD -4592.282%
Rhythm Pharmaceuticals, Inc. -58.82 Million USD 1351.706%
Nuvalent, Inc. -335.38 Million USD 319.527%
ABVC BioPharma, Inc. 1.73 Million USD -42352.205%
Carisma Therapeutics, Inc. -74.48 Million USD 1088.515%
Unicycive Therapeutics, Inc. -8.89 Million USD 8381.957%
OmniAb, Inc. 9.2 Million USD -7900.283%
Anew Medical, Inc. 1.43 Million USD -51298.533%
Fennec Pharmaceuticals Inc. 16.38 Million USD -4394.427%
Lipocine Inc. -4.75 Million USD 15585.367%
Lexeo Therapeutics, Inc. Common Stock -109.82 Million USD 770.381%
Nautilus Biotechnology, Inc. 15.23 Million USD -4733.996%
SAB Biotherapeutics, Inc. -50.65 Million USD 1553.376%
G1 Therapeutics, Inc. 24.89 Million USD -2857.842%
Bellerophon Therapeutics, Inc. -6.72 Million USD 11054.709%
Sage Therapeutics, Inc. -65.82 Million USD 1218.486%
Ocugen, Inc. -32.52 Million USD 2363.971%
Mind Medicine (MindMed) Inc. -85.57 Million USD 960.375%
Q32 Bio Inc. -37.94 Million USD 2040.197%
Brainstorm Cell Therapeutics Inc. -628 Thousand USD 117339.809%
Alumis Inc. Common Stock -13.52 Million USD 5542.132%
Equillium, Inc. -22.39 Million USD 3388.076%
Kyverna Therapeutics, Inc. -25.56 Million USD 2979.639%
Coya Therapeutics, Inc. -32.62 Million USD 2356.632%
CNS Pharmaceuticals, Inc. -247.91 Thousand USD 297083.24%
Galera Therapeutics, Inc. 134.04 Million USD -449.28%
Evelo Biosciences, Inc. 3.19 Million USD -22922.702%
Comera Life Sciences Holdings, Inc. 328.44 Thousand USD -224069.942%
Dominari Holdings Inc. 195 Thousand USD -377472.308%
Edesa Biotech, Inc. -5.26 Million USD 14079.088%
vTv Therapeutics Inc. -8.91 Million USD 8356.88%
Bio-Techne Corporation 267.74 Million USD -174.986%
Agios Pharmaceuticals, Inc. -16.2 Million USD 4642.328%
Harmony Biosciences Holdings, Inc. -118.09 Million USD 723.458%
Prelude Therapeutics Incorporated -8.4 Million USD 8861.942%
Candel Therapeutics, Inc. -12.65 Million USD 5919.825%
iTeos Therapeutics, Inc. -245.11 Million USD 400.371%
Nkarta, Inc. 57.29 Million USD -1184.954%
BioCardia, Inc. 212 Thousand USD -347195.283%
Iterum Therapeutics plc 13.43 Million USD -5378.985%