Spruce Biosciences, Inc. (SPRB)

USD 0.28

(-3.66%)

Net Debt Summary of Spruce Biosciences, Inc.

  • Spruce Biosciences, Inc.'s latest annual net debt in 2023 was -91.73 Million USD , down -400.96% from previous year.
  • Spruce Biosciences, Inc.'s latest quarterly net debt in 2024 Q1 was -77 Million USD , up 16.06% from previous quarter.
  • Spruce Biosciences, Inc. reported annual net debt of -18.31 Million USD in 2022, up 49.94% from previous year.
  • Spruce Biosciences, Inc. reported annual net debt of -36.57 Million USD in 2021, up 75.78% from previous year.
  • Spruce Biosciences, Inc. reported quarterly net debt of -77 Million USD for 2024 Q1, up 16.06% from previous quarter.
  • Spruce Biosciences, Inc. reported quarterly net debt of -68.19 Million USD for 2023 Q1, down -275.27% from previous quarter.

Annual Net Debt Chart of Spruce Biosciences, Inc. (2023 - 2018)

Historical Annual Net Debt of Spruce Biosciences, Inc. (2023 - 2018)

Year Net Debt Net Debt Growth
2023 -91.73 Million USD -400.96%
2022 -18.31 Million USD 49.94%
2021 -36.57 Million USD 75.78%
2020 -151.02 Million USD -29086.76%
2019 521 Thousand USD 112.67%
2018 -4.11 Million USD 0.0%

Peer Net Debt Comparison of Spruce Biosciences, Inc.

Name Net Debt Net Debt Difference
AbCellera Biologics Inc. -55.94 Million USD -63.979%
Alkermes plc -166.73 Million USD 44.986%
Agenus Inc. 274.13 Million USD 133.461%
Alnylam Pharmaceuticals, Inc. 1.86 Billion USD 104.906%
Aptorum Group Limited 1.35 Million USD 6859.535%
Ardelyx, Inc. 34.51 Million USD 365.792%
Arrowhead Pharmaceuticals, Inc. 4.28 Million USD 2243.224%
Bicycle Therapeutics plc -481.46 Million USD 80.948%
BioXcel Therapeutics, Inc. 36.16 Million USD 353.657%
ChromaDex Corporation -24.04 Million USD -281.445%
Chimerix, Inc. -25.51 Million USD -259.486%
Corbus Pharmaceuticals Holdings, Inc. 6.96 Million USD 1416.432%
Caribou Biosciences, Inc. -23.67 Million USD -287.422%
CRISPR Therapeutics AG -150.84 Million USD 39.189%
Precision BioSciences, Inc. -85.41 Million USD -7.4%
Dyadic International, Inc. -6.37 Million USD -1338.203%
Eton Pharmaceuticals, Inc. -15.93 Million USD -475.723%
Fortress Biotech, Inc. 7.66 Million USD 1296.738%
Lantern Pharma Inc. -21.7 Million USD -322.655%
HOOKIPA Pharma Inc. -110.53 Million USD 17.014%
Inhibikase Therapeutics, Inc. -8.54 Million USD -973.722%
Incyte Corporation -3.17 Billion USD 97.111%
IO Biotech, Inc. -140.69 Million USD 34.804%
Jaguar Health, Inc. 29.39 Million USD 412.102%
Novavax, Inc. -298.29 Million USD 69.248%
Janux Therapeutics, Inc. 5.33 Million USD 1818.756%
Opthea Limited 28.15 Million USD 425.775%
Ligand Pharmaceuticals Incorporated -16.78 Million USD -446.37%
ContextLogic Inc. -232 Million USD 60.461%
MiMedx Group, Inc. -33.9 Million USD -170.582%
Pyxis Oncology, Inc. 10.19 Million USD 999.755%
TransCode Therapeutics, Inc. -2.31 Million USD -3858.953%
NextCure, Inc. -6.47 Million USD -1316.242%
Ocuphire Pharma, Inc. -50.5 Million USD -81.64%
Oncternal Therapeutics, Inc. -6.37 Million USD -1338.0%
Outlook Therapeutics, Inc. 12.16 Million USD 854.156%
Vaxcyte, Inc. -368.22 Million USD 75.089%
PDS Biotechnology Corporation -32.7 Million USD -180.444%
Madrigal Pharmaceuticals, Inc. 17.27 Million USD 630.906%
Pharming Group N.V. 109.8 Million USD 183.54%
Pieris Pharmaceuticals, Inc. -17.39 Million USD -427.305%
Avidity Biosciences, Inc. -175.23 Million USD 47.652%
Reviva Pharmaceuticals Holdings, Inc. -18.51 Million USD -395.306%
Reviva Pharmaceuticals Holdings, Inc. -18.51 Million USD -395.306%
Sangamo Therapeutics, Inc. -7.1 Million USD -1191.972%
Sol-Gel Technologies Ltd. -5.86 Million USD -1465.358%
Acelyrin, Inc. -216.9 Million USD 57.709%
Salarius Pharmaceuticals, Inc. -5.61 Million USD -1535.038%
SELLAS Life Sciences Group, Inc. -1.72 Million USD -5220.766%
Summit Therapeutics Inc. 34.67 Million USD 364.55%
Sensei Biotherapeutics, Inc. -6.8 Million USD -1248.376%
Senti Biosciences, Inc. 1.74 Million USD 5371.839%
Stoke Therapeutics, Inc. -184.6 Million USD 50.311%
Syros Pharmaceuticals, Inc. -77.45 Million USD -18.436%
Alaunos Therapeutics, Inc. -6.06 Million USD -1413.197%
Telomir Pharmaceuticals, Inc. Common Stock 99.76 Thousand USD 92042.387%
Entrada Therapeutics, Inc. 628 Thousand USD 14706.688%
VistaGen Therapeutics, Inc. -117.04 Million USD 21.629%
Wave Life Sciences Ltd. -168.23 Million USD 45.474%
Sorrento Therapeutics, Inc. 110.87 Million USD 182.737%
TRACON Pharmaceuticals, Inc. -7.59 Million USD -1107.609%
Barinthus Biotherapeutics plc -129.11 Million USD 28.954%
Psyence Biomedical Ltd. 6.89 Million USD 1430.462%
Phathom Pharmaceuticals, Inc. -242.36 Million USD 62.152%
Immix Biopharma, Inc. -17.5 Million USD -423.878%
Keros Therapeutics, Inc. -316.7 Million USD 71.036%
MEI Pharma, Inc. -3.7 Million USD -2375.843%
Windtree Therapeutics, Inc. 12.51 Million USD 833.195%
Xeris Biopharma Holdings, Inc. 161.74 Million USD 156.714%
Rigel Pharmaceuticals, Inc. 27.79 Million USD 430.047%
Fortress Biotech, Inc. 7.66 Million USD 1296.738%
Precigen, Inc. -481 Thousand USD -18970.686%
Clearside Biomedical, Inc. 14.08 Million USD 751.445%
AlloVir, Inc. -62.69 Million USD -46.319%
C4 Therapeutics, Inc. -55.61 Million USD -64.94%
Fate Therapeutics, Inc. 61.66 Million USD 248.753%
ImmuCell Corporation 10.99 Million USD 934.625%
IDEAYA Biosciences, Inc. -154.14 Million USD 40.491%
Onconetix, Inc. 5.33 Million USD 1820.549%
PureTech Health plc -167.19 Million USD 45.137%
VYNE Therapeutics Inc. -30.46 Million USD -201.149%
Elevation Oncology, Inc. -19.11 Million USD -379.81%
Kintara Therapeutics, Inc. -4.9 Million USD -1768.609%
Seer, Inc. -4.24 Million USD -2063.443%
Verrica Pharmaceuticals Inc. -24.03 Million USD -281.62%
Innoviva, Inc. 255.56 Million USD 135.893%
Aadi Bioscience, Inc. -55.86 Million USD -64.202%
ESSA Pharma Inc. -33.62 Million USD -172.831%
GlycoMimetics, Inc. -40.98 Million USD -123.817%
GT Biopharma, Inc. -1.02 Million USD -8884.329%
Inhibrx Biosciences, Inc. -67.78 Million USD -35.329%
Akebia Therapeutics, Inc. 61.25 Million USD 249.746%
Catalyst Pharmaceuticals, Inc. -134.07 Million USD 31.585%
Longboard Pharmaceuticals, Inc. -13.85 Million USD -562.024%
Orchestra BioMed Holdings, Inc. -28.87 Million USD -217.713%
Alzamend Neuro, Inc. -75.33 Thousand USD -121664.409%
Rocket Pharmaceuticals, Inc. -30.86 Million USD -197.226%
Aptose Biosciences Inc. -8.19 Million USD -1019.361%
ZyVersa Therapeutics, Inc. -3.12 Million USD -2831.591%
Soligenix, Inc. -4.95 Million USD -1752.534%
Century Therapeutics, Inc. 847 Thousand USD 10929.988%
Kura Oncology, Inc. -20.11 Million USD -355.96%
TScan Therapeutics, Inc. -40.92 Million USD -124.136%
Intensity Therapeutics, Inc. -8.39 Million USD -992.284%
Ocean Biomedical, Inc. 1.82 Million USD 5135.42%
CytomX Therapeutics, Inc. -3.19 Million USD -2769.252%
Autolus Therapeutics plc -186.59 Million USD 50.841%
Mineralys Therapeutics, Inc. -49.3 Million USD -86.05%
EyePoint Pharmaceuticals, Inc. -275.79 Million USD 66.74%
Eterna Therapeutics Inc. 34.26 Million USD 367.684%
Adaptive Biotechnologies Corporation 164.36 Million USD 155.808%
GRI Bio, Inc. -1.79 Million USD -5013.155%
Xenetic Biosciences, Inc. -8.98 Million USD -921.146%
Tenaya Therapeutics, Inc. -33.25 Million USD -175.822%
IGM Biosciences, Inc. -72.6 Million USD -26.339%
INmune Bio, Inc. -25.41 Million USD -260.985%
Heron Therapeutics, Inc. 150.95 Million USD 160.768%
SAB Biotherapeutics, Inc. -50.65 Million USD -81.073%
Pasithea Therapeutics Corp. -16.24 Million USD -464.514%
Entero Therapeutics, Inc. -2.88 Million USD -3079.631%
Milestone Pharmaceuticals Inc. 38.01 Million USD 341.299%
X4 Pharmaceuticals, Inc. -41.18 Million USD -122.727%
Atara Biotherapeutics, Inc. 31.88 Million USD 387.69%
Coherus BioSciences, Inc. 377.95 Million USD 124.27%
Verastem, Inc. -37.27 Million USD -146.07%
Abeona Therapeutics Inc. -9.07 Million USD -911.022%
Pliant Therapeutics, Inc. -51.86 Million USD -76.873%
Tonix Pharmaceuticals Holding Corp. -15.13 Million USD -506.079%
Histogen Inc. -7.48 Million USD -1125.19%
Aprea Therapeutics, Inc. -21.6 Million USD -324.542%
Surrozen, Inc. -32.66 Million USD -180.829%
Organovo Holdings, Inc. -1.5 Million USD -5986.928%
Lixte Biotechnology Holdings, Inc. -4.2 Million USD -2082.235%
Ovid Therapeutics Inc. 18.96 Million USD 583.803%
Panbela Therapeutics, Inc. 2.61 Million USD 3606.498%
CASI Pharmaceuticals, Inc. 4.15 Million USD 2307.17%
Cadrenal Therapeutics, Inc. Common Stock -8.38 Million USD -994.48%
Centessa Pharmaceuticals plc -43.44 Million USD -111.155%
Hepion Pharmaceuticals, Inc. -14.57 Million USD -529.285%
Arcturus Therapeutics Holdings Inc. -316.78 Million USD 71.044%
BioRestorative Therapies, Inc. -722.06 Thousand USD -12603.93%
Apollomics, Inc. -27.39 Million USD -234.842%
Amarin Corporation plc -191.04 Million USD 51.984%
Mesoblast Limited 55.96 Million USD 263.912%
Turnstone Biologics Corp. -14.58 Million USD -528.977%
Kymera Therapeutics, Inc. -25.29 Million USD -262.684%
Synaptogenix, Inc. -28.66 Million USD -220.046%
Tiziana Life Sciences Ltd -936 Thousand USD -9700.214%
Aurinia Pharmaceuticals Inc. 48.73 Million USD 288.234%
BriaCell Therapeutics Corp. -862.08 Thousand USD -10540.433%
Monopar Therapeutics Inc. -7.26 Million USD -1162.441%
Exelixis, Inc. -73.05 Million USD -25.572%
Better Therapeutics, Inc. -860 Thousand USD -10566.279%
Nurix Therapeutics, Inc. -24.01 Million USD -282.001%
Apellis Pharmaceuticals, Inc. -241.37 Million USD 61.996%
NLS Pharmaceutics AG 736.06 Thousand USD 12562.198%
Dermata Therapeutics, Inc. -7.43 Million USD -1133.239%
Aridis Pharmaceuticals, Inc. 1.25 Million USD 7414.992%
Gritstone bio, Inc. 39.49 Million USD 332.287%
Jasper Therapeutics, Inc. -84.1 Million USD -9.071%
TNF Pharmaceuticals, Inc. -2.63 Million USD -3384.997%
Avid Bioservices, Inc. 169.72 Million USD 154.045%
Insmed Incorporated 721.62 Million USD 112.712%
Virpax Pharmaceuticals, Inc. -9.14 Million USD -903.445%
MediWound Ltd. -5.32 Million USD -1623.6%
OmniAb, Inc. 9.2 Million USD 1096.74%
Alector, Inc. -35.63 Million USD -157.401%
Seres Therapeutics, Inc. 85.97 Million USD 206.699%
Checkpoint Therapeutics, Inc. -4.92 Million USD -1761.404%
Viracta Therapeutics, Inc. 13.23 Million USD 792.877%
Zai Lab Limited -775 Million USD 88.164%
Revance Therapeutics, Inc. 340.55 Million USD 126.935%
Aura Biosciences, Inc. -21.52 Million USD -326.156%
Lyell Immunopharma, Inc. -82.48 Million USD -11.215%
Immunic, Inc. -45.34 Million USD -102.316%
Tarsus Pharmaceuticals, Inc. -193.21 Million USD 52.524%
Veracyte, Inc. -203.82 Million USD 54.995%
InMed Pharmaceuticals Inc. 638.29 Million USD 114.371%
FibroGen, Inc. 56.76 Million USD 261.59%
SeaStar Medical Holding Corporation 8.9 Million USD 1130.095%
Adial Pharmaceuticals, Inc. -2.82 Million USD -3144.688%
Sonnet BioTherapeutics Holdings, Inc. -2.07 Million USD -4330.656%
Jazz Pharmaceuticals plc 4.59 Billion USD 101.998%
Cyclacel Pharmaceuticals, Inc. -3.34 Million USD -2645.585%
Amylyx Pharmaceuticals, Inc. -165.96 Million USD 44.729%
TG Therapeutics, Inc. 17.86 Million USD 613.548%
Galecto, Inc. -21.21 Million USD -332.362%
Calithera Biosciences, Inc. -23.78 Million USD -285.663%
Fortrea Holdings Inc. 1.56 Billion USD 105.845%
KalVista Pharmaceuticals, Inc. -24.47 Million USD -274.837%
Aptevo Therapeutics Inc. -11.5 Million USD -697.167%
XBiotech Inc. -200.02 Million USD 54.14%
Jasper Therapeutics, Inc. -84.1 Million USD -9.071%
Lyra Therapeutics, Inc. 4.52 Million USD 2125.839%
Foghorn Therapeutics Inc. -35.26 Million USD -160.131%
Y-mAbs Therapeutics, Inc. -77.21 Million USD -18.794%
Theravance Biopharma, Inc. 5.69 Million USD 1711.843%
Ultragenyx Pharmaceutical Inc. -170.41 Million USD 46.173%
Metagenomi, Inc. Common Stock -92.37 Million USD 0.697%
Vaxxinity, Inc. 10.13 Million USD 1005.349%
BioCryst Pharmaceuticals, Inc. 736.26 Million USD 112.459%
Gain Therapeutics, Inc. -10.76 Million USD -751.911%
Cartesian Therapeutics, Inc. -65.95 Million USD -39.078%
NexImmune, Inc. -3.13 Million USD -2827.264%
Creative Medical Technology Holdings, Inc. -3.45 Million USD -2556.782%
Marker Therapeutics, Inc. -15.11 Million USD -507.023%
Regeneron Pharmaceuticals, Inc. -27.1 Million USD -238.487%
Chemomab Therapeutics Ltd. -8.97 Million USD -921.941%
Scopus BioPharma Inc. -124.57 Thousand USD -73534.357%
RAPT Therapeutics, Inc. -40.57 Million USD -126.092%
Ainos, Inc. 4.07 Million USD 2349.427%
Pluri Inc. 22.82 Million USD 501.813%
Prothena Corporation plc -608.34 Million USD 84.921%
Adaptimmune Therapeutics plc -118.75 Million USD 22.758%
Celularity Inc. 65.19 Million USD 240.712%
Rallybio Corporation -24.1 Million USD -280.591%
Cue Biopharma, Inc. -33.81 Million USD -171.238%
MeiraGTx Holdings plc -40.3 Million USD -127.607%
Omeros Corporation 331.17 Million USD 127.698%
Humacyte, Inc. -22.48 Million USD -307.943%
Immunocore Holdings plc -358.59 Million USD 74.42%
Cocrystal Pharma, Inc. -24.57 Million USD -273.266%
Cidara Therapeutics, Inc. -30.9 Million USD -196.851%
Blueprint Medicines Corporation 702.83 Million USD 113.051%
CalciMedica, Inc. -5.53 Million USD -1558.77%
Cabaletta Bio, Inc. -188.22 Million USD 51.264%
Marinus Pharmaceuticals, Inc. -10.21 Million USD -798.081%
Scholar Rock Holding Corporation -40.03 Million USD -129.113%
Sana Biotechnology, Inc. -33.25 Million USD -175.855%
Pulmatrix, Inc. -10.41 Million USD -780.58%
Elicio Therapeutics, Inc. -5.97 Million USD -1434.716%
Vigil Neuroscience, Inc. -38.14 Million USD -140.496%
Intellia Therapeutics, Inc. -111.4 Million USD 17.659%
Adlai Nortye Ltd. American Depositary Shares -59.94 Million USD -53.026%
Cytokinetics, Incorporated 642.37 Million USD 114.28%
Eloxx Pharmaceuticals, Inc. -5.82 Million USD -1475.305%
Nutriband Inc. -251.65 Thousand USD -36350.407%
Protara Therapeutics, Inc. -34.11 Million USD -168.853%
Vor Biopharma Inc. 4.3 Million USD 2233.256%
Roivant Sciences Ltd. -6.03 Billion USD 98.48%
Evogene Ltd. -19.63 Million USD -367.2%
ProKidney Corp. -56.23 Million USD -63.116%
Applied Therapeutics, Inc. -48.67 Million USD -88.466%
Hoth Therapeutics, Inc. -9.23 Million USD -893.051%
BridgeBio Pharma, Inc. 1.36 Billion USD 106.726%
CorMedix Inc. -43.05 Million USD -113.065%
BioLineRx Ltd. 7.33 Million USD 1350.409%
Tango Therapeutics, Inc. -27.46 Million USD -233.989%
Galectin Therapeutics Inc. 46.14 Million USD 298.778%
Atai Life Sciences N.V. -28.55 Million USD -221.206%
Renovaro Biosciences Inc. 2.23 Million USD 4212.477%
Aerovate Therapeutics, Inc. -22.81 Million USD -302.042%
Zentalis Pharmaceuticals, Inc. 17.73 Million USD 617.226%
Sagimet Biosciences Inc. -75.07 Million USD -22.186%
MediciNova, Inc. -50.78 Million USD -80.629%
Praxis Precision Medicines, Inc. -78.8 Million USD -16.401%
Cardio Diagnostics Holdings, Inc. -22.49 Thousand USD -407679.507%
GeoVax Labs, Inc. -6.45 Million USD -1321.6%
Axsome Therapeutics, Inc. -199.82 Million USD 54.094%
Biomea Fusion, Inc. -166.57 Million USD 44.93%
PTC Therapeutics, Inc. -178.97 Million USD 48.747%
Mereo BioPharma Group plc -51.46 Million USD -78.224%
Cullinan Oncology, Inc. -94.84 Million USD 3.283%
Syndax Pharmaceuticals, Inc. -293.75 Million USD 68.774%
Absci Corporation -72.59 Million USD -26.353%
NRx Pharmaceuticals, Inc. 4.56 Million USD 2108.979%
4D Molecular Therapeutics, Inc. -234.43 Million USD 60.872%
Dyne Therapeutics, Inc. -94.21 Million USD 2.633%
Kiniksa Pharmaceuticals, Ltd. -95.69 Million USD 4.144%
Ventyx Biosciences, Inc. -39.07 Million USD -134.766%
Allakos Inc. -24.97 Million USD -267.287%
Imunon, Inc. -4.21 Million USD -2076.868%
Fulcrum Therapeutics, Inc. -14.74 Million USD -522.236%
Corcept Therapeutics Incorporated -135.4 Million USD 32.253%
BioAtla, Inc. -109.01 Million USD 15.853%
NLS Pharmaceutics AG 736.06 Thousand USD 12562.198%
Bio-Path Holdings, Inc. -939 Thousand USD -9668.903%
Allogene Therapeutics, Inc. 11.96 Million USD 866.589%
Larimar Therapeutics, Inc. -21.2 Million USD -332.627%
XOMA Corporation -29 Million USD -216.31%
Kezar Life Sciences, Inc. -16.56 Million USD -453.925%
Cara Therapeutics, Inc. -9.01 Million USD -917.413%
aTyr Pharma, Inc. -7.44 Million USD -1131.44%
Aligos Therapeutics, Inc. -124.63 Million USD 26.402%
Akero Therapeutics, Inc. -208.16 Million USD 55.934%
Viridian Therapeutics, Inc. -81.77 Million USD -12.168%
Eliem Therapeutics, Inc. -92.76 Million USD 1.114%
EyeGate Pharmaceuticals, Inc. -859.18 Thousand USD -10576.409%
Akari Therapeutics, Plc -3.84 Million USD -2285.696%
Tevogen Bio Holdings Inc. 1.62 Million USD 5752.262%
Halozyme Therapeutics, Inc. 1.38 Billion USD 106.643%
Lexaria Bioscience Corp. -1.18 Million USD -7620.503%
UroGen Pharma Ltd. 4.39 Million USD 2189.046%
Sutro Biopharma, Inc. 113.48 Million USD 180.833%
ZIVO Bioscience, Inc. 71.96 Thousand USD 127570.054%
Orgenesis Inc. 21.78 Million USD 521.089%
Entera Bio Ltd. -10.62 Million USD -763.016%
GH Research PLC -78.07 Million USD -17.487%
Lisata Therapeutics, Inc. -22.28 Million USD -311.567%
Reneo Pharmaceuticals, Inc. -26.65 Million USD -244.086%
Xencor, Inc. 29.64 Million USD 409.439%
60 Degrees Pharmaceuticals, Inc. -1.96 Million USD -4556.79%
Replimune Group, Inc. 1.41 Million USD 6596.459%
Coeptis Therapeutics Holdings, Inc. -244.9 Thousand USD -37354.881%
Vanda Pharmaceuticals Inc. -126.41 Million USD 27.439%
Lexaria Bioscience Corp. -1.18 Million USD -7620.503%
Portage Biotech Inc. -4.98 Million USD -1741.598%
Cardio Diagnostics Holdings, Inc. -22.49 Thousand USD -407679.507%
Olema Pharmaceuticals, Inc. -66.12 Million USD -38.728%
OncoCyte Corporation -6.56 Million USD -1297.684%
Qualigen Therapeutics, Inc. 897.41 Thousand USD 10321.604%
Processa Pharmaceuticals, Inc. -4.55 Million USD -1913.547%
Purple Biotech Ltd. -14.13 Million USD -548.819%
CollPlant Biotechnologies Ltd. -23.75 Million USD -286.134%
scPharmaceuticals Inc. -6.54 Million USD -1301.528%
ProMIS Neurosciences, Inc. -16.69 Million USD -449.539%
HilleVax, Inc. -165.48 Million USD 44.569%
NeuroSense Therapeutics Ltd. -2.53 Million USD -3514.263%
Tharimmune, Inc. -10.93 Million USD -738.839%
Genprex, Inc. -6.73 Million USD -1261.458%
Neumora Therapeutics, Inc. Common Stock -368.8 Million USD 75.128%
Atossa Therapeutics, Inc. -88.46 Million USD -3.697%
XTL Biopharmaceuticals Ltd. -1.4 Million USD -6447.466%
Virios Therapeutics, Inc. -3.31 Million USD -2665.496%
OKYO Pharma Limited -826.84 Thousand USD -10993.937%
Savara Inc. 153 Thousand USD 60054.248%
Curis, Inc. -23.88 Million USD -284.016%
Daré Bioscience, Inc. -5.15 Million USD -1678.433%
Carmell Therapeutics Corporation -776.01 Thousand USD -11720.693%
Titan Pharmaceuticals, Inc. -6.2 Million USD -1377.61%
Achieve Life Sciences, Inc. 1.18 Million USD 7840.928%
BeiGene, Ltd. -2.25 Billion USD 95.929%
Kiromic BioPharma, Inc. 12.33 Million USD 843.445%
Revolution Medicines, Inc. Warrant -608.2 Million USD 84.918%
Protagonist Therapeutics, Inc. -185.58 Million USD 50.573%
Erasca, Inc. -37.21 Million USD -146.48%
bluebird bio, Inc. 108.57 Million USD 184.488%
Protagenic Therapeutics, Inc. -1.28 Million USD -7022.486%
BioMarin Pharmaceutical Inc. 378.74 Million USD 124.219%
DBV Technologies S.A. -126.98 Million USD 27.764%
Protagenic Therapeutics, Inc. -1.28 Million USD -7022.486%
Moderna, Inc. -2.9 Billion USD 96.845%
Vincerx Pharma, Inc. -10.35 Million USD -786.109%
Fresh Tracks Therapeutics, Inc. -10.86 Million USD -744.038%
Molecular Templates, Inc. 707 Thousand USD 13074.54%
Acrivon Therapeutics, Inc. Common Stock -31.37 Million USD -192.404%
Travere Therapeutics, Inc. 346.6 Million USD 126.465%
Monte Rosa Therapeutics, Inc. -82.06 Million USD -11.781%
Celldex Therapeutics, Inc. -32.27 Million USD -184.24%
Cogent Biosciences, Inc. -34.37 Million USD -166.843%
MacroGenics, Inc. -66.98 Million USD -36.941%
RenovoRx, Inc. -1.17 Million USD -7720.119%
Adicet Bio, Inc. -138.78 Million USD 33.906%
Prime Medicine, Inc. -27.94 Million USD -228.299%
Aditxt, Inc. 18.12 Million USD 606.211%
Adagene Inc. -87.62 Million USD -4.682%
Estrella Immunopharma, Inc. -4.16 Million USD -2102.175%
Quantum-Si incorporated -118.55 Million USD 22.628%
Maravai LifeSciences Holdings, Inc. 36 Million USD 354.77%
Acurx Pharmaceuticals, Inc. -7.47 Million USD -1127.291%
Voyager Therapeutics, Inc. -48.5 Million USD -89.099%
SciSparc Ltd. -2.06 Million USD -4342.131%
Vericel Corporation 1.27 Million USD 7283.242%
Revelation Biosciences, Inc. -11.99 Million USD -664.946%
Minerva Neurosciences, Inc. 41 Million USD 323.709%
Generation Bio Co. 31.44 Million USD 391.688%
Astria Therapeutics, Inc. -175.36 Million USD 47.692%
Black Diamond Therapeutics, Inc. -30.92 Million USD -196.64%
Arcutis Biotherapeutics, Inc. 116.59 Million USD 178.675%
Invivyd, Inc. -198.47 Million USD 53.783%
Relay Therapeutics, Inc. -90.27 Million USD -1.617%
Quoin Pharmaceuticals, Ltd. -2.39 Million USD -3725.768%
Spero Therapeutics, Inc. -70.79 Million USD -29.58%
Artelo Biosciences, Inc. -6.82 Million USD -1244.029%
2seventy bio, Inc. 181.71 Million USD 150.48%
ADMA Biologics, Inc. 90.06 Million USD 201.848%
Clene Inc. 3.34 Million USD 2846.407%
Capricor Therapeutics, Inc. -9.08 Million USD -909.942%
Boundless Bio, Inc. Common Stock -21.51 Million USD -326.433%
GeoVax Labs, Inc. -6.45 Million USD -1321.6%
Recursion Pharmaceuticals, Inc. -344.12 Million USD 73.344%
Citius Pharmaceuticals, Inc. -25.99 Million USD -252.812%
Contineum Therapeutics, Inc. Class A Common Stock 177.66 Million USD 151.631%
Relmada Therapeutics, Inc. -4.09 Million USD -2141.928%
Finch Therapeutics Group, Inc. 5 Million USD 1933.866%
ALX Oncology Holdings Inc. -5.2 Million USD -1660.991%
Vir Biotechnology, Inc. -130.3 Million USD 29.603%
Evaxion Biotech A/S 5.28 Million USD 1835.062%
Ocular Therapeutix, Inc. -112.56 Million USD 18.511%
Verve Therapeutics, Inc. -131.27 Million USD 30.123%
Trevena, Inc. 2.25 Million USD 4162.445%
Surrozen, Inc. -32.66 Million USD -180.829%
Tyra Biosciences, Inc. -51.51 Million USD -78.082%
Cingulate Inc. 3.08 Million USD 3075.655%
Galmed Pharmaceuticals Ltd. -2.93 Million USD -3023.255%
Unity Biotechnology, Inc. 7.18 Million USD 1376.332%
Tenax Therapeutics, Inc. -9.29 Million USD -887.275%
Terns Pharmaceuticals, Inc. -79.32 Million USD -15.641%
ACADIA Pharmaceuticals Inc. -131.45 Million USD 30.218%
Connect Biopharma Holdings Limited -105.54 Million USD 13.087%
Clearmind Medicine Inc. -3.94 Million USD -2226.615%
Kronos Bio, Inc. -36.05 Million USD -154.424%
Bolt Biotherapeutics, Inc. 9.4 Million USD 1074.918%
CERo Therapeutics Holdings, Inc. 1.45 Million USD 6390.947%
Viking Therapeutics, Inc. -54.25 Million USD -69.069%
Statera Biopharma, Inc. 14.41 Million USD 736.289%
ImmunityBio, Inc. 618.22 Million USD 114.838%
Korro Bio, Inc. -132.94 Million USD 31.001%
Kineta, Inc. -4.54 Million USD -1920.04%
BioVie Inc. -17.73 Million USD -417.303%
Codexis, Inc. -43.27 Million USD -111.99%
Celularity Inc. 65.19 Million USD 240.712%
Crinetics Pharmaceuticals, Inc. -3.16 Million USD -2794.604%
Celcuity Inc. 6.78 Million USD 1452.25%
Virax Biolabs Group Limited -3.36 Million USD -2626.048%
Cibus, Inc. -8.07 Million USD -1035.553%
Eledon Pharmaceuticals, Inc. -4.22 Million USD -2069.071%
eFFECTOR Therapeutics, Inc. 4.57 Million USD 2107.221%
IN8bio, Inc. -16.38 Million USD -459.705%
Kodiak Sciences Inc. -103.87 Million USD 11.692%
Annexon, Inc. -193.75 Million USD 52.657%
Adverum Biotechnologies, Inc. 36 Thousand USD 254905.556%
Assembly Biosciences, Inc. -17.49 Million USD -424.201%
Avalo Therapeutics, Inc. -3.51 Million USD -2511.159%
Ionis Pharmaceuticals, Inc. 1.05 Billion USD 108.701%
Eyenovia, Inc. 1.25 Million USD 7387.666%
Puma Biotechnology, Inc. 26.9 Million USD 440.94%
Conduit Pharmaceuticals Inc. -3.24 Million USD -2728.554%
Xilio Therapeutics, Inc. -33.24 Million USD -175.905%
Arcellx, Inc. -296.95 Million USD 69.11%
Cardiff Oncology, Inc. -19.5 Million USD -370.266%
Enanta Pharmaceuticals, Inc. -58.87 Million USD -55.805%
Regulus Therapeutics Inc. -20.72 Million USD -342.563%
Moolec Science SA 117.61 Thousand USD 78091.09%
Acumen Pharmaceuticals, Inc. -38.39 Million USD -138.886%
Geron Corporation 14.76 Million USD 721.435%
LAVA Therapeutics N.V. -37.91 Million USD -141.917%
Royalty Pharma plc 5.65 Billion USD 101.621%
Atea Pharmaceuticals, Inc. -141.42 Million USD 35.137%
Greenwich LifeSciences, Inc. -6.98 Million USD -1212.411%
TFF Pharmaceuticals, Inc. -5.36 Million USD -1610.468%
Mersana Therapeutics, Inc. -140.73 Million USD 34.819%
Humacyte, Inc. -22.48 Million USD -307.943%
Structure Therapeutics Inc. -124.33 Million USD 26.226%
89bio, Inc. -289.05 Million USD 68.265%
PMV Pharmaceuticals, Inc. -25.24 Million USD -263.402%
Avenue Therapeutics, Inc. -1.78 Million USD -5044.7%
Genelux Corporation -6.89 Million USD -1229.613%
Trevi Therapeutics, Inc. -31.05 Million USD -195.341%
Lexicon Pharmaceuticals, Inc. 83.59 Million USD 209.726%
Notable Labs, Ltd. -9.77 Million USD -838.318%
Liquidia Corporation -80.17 Million USD -14.411%
Mustang Bio, Inc. -3.73 Million USD -2355.3%
Immunovant, Inc. -635.22 Million USD 85.559%
Quantum-Si incorporated -118.55 Million USD 22.628%
Arbutus Biopharma Corporation -17.56 Million USD -422.261%
DiaMedica Therapeutics Inc. -4.14 Million USD -2114.096%
Vera Therapeutics, Inc. 8.02 Million USD 1242.768%
Acasti Pharma Inc. -23 Million USD -298.739%
MiNK Therapeutics, Inc. -3.36 Million USD -2624.198%
Pasithea Therapeutics Corp. -16.24 Million USD -464.514%
Xenon Pharmaceuticals Inc. -137.74 Million USD 33.404%
Elevai Labs, Inc. Common Stock -3.11 Million USD -2843.496%
NeuroBo Pharmaceuticals, Inc. -22.23 Million USD -312.603%
Tempest Therapeutics, Inc. -18.56 Million USD -393.995%
Soleno Therapeutics, Inc. -169.27 Million USD 45.811%
PepGen Inc. -60.67 Million USD -51.195%
Moleculin Biotech, Inc. -22.97 Million USD -299.243%
United Therapeutics Corporation -507.7 Million USD 81.932%
Nuvectis Pharma, Inc. -19.12 Million USD -379.609%
Solid Biosciences Inc. -47.75 Million USD -92.105%
BriaCell Therapeutics Corp. -862.08 Thousand USD -10540.433%
Immuneering Corporation -54.94 Million USD -66.955%
Lixte Biotechnology Holdings, Inc. -4.2 Million USD -2082.235%
Silo Pharma, Inc. -3.52 Million USD -2502.78%
Belite Bio, Inc -87.27 Million USD -5.109%
XOMA Corporation -29 Million USD -216.31%
ARS Pharmaceuticals, Inc. -70.69 Million USD -29.751%
Bionomics Limited 227 Million USD 140.408%
Apogee Therapeutics, Inc. -116.28 Million USD 21.114%
Alpha Tau Medical Ltd. -2.53 Million USD -3521.398%
uniQure N.V. -102.95 Million USD 10.899%
Cassava Sciences, Inc. -121.13 Million USD 24.275%
Estrella Immunopharma, Inc. -4.16 Million USD -2102.175%
Poseida Therapeutics, Inc. 40.95 Million USD 323.999%
Forte Biosciences, Inc. -11.96 Million USD -666.909%
Anebulo Pharmaceuticals, Inc. -3.09 Million USD -2864.579%
Enlivex Therapeutics Ltd. 106 Thousand USD 86637.736%
Conduit Pharmaceuticals Inc. -3.24 Million USD -2728.554%
SeaStar Medical Holding Corporation 8.9 Million USD 1130.095%
FibroBiologics, Inc. Common Stock -7.41 Million USD -1136.92%
Altimmune, Inc. -134.48 Million USD 31.793%
Amicus Therapeutics, Inc. 198.06 Million USD 146.313%
Alpha Tau Medical Ltd. -2.53 Million USD -3521.398%
Compugen Ltd. -12.9 Million USD -610.865%
Peak Bio, Inc. 10.34 Million USD 987.124%
Zevra Therapeutics, Inc. -283 Thousand USD -32313.428%
Benitec Biopharma Inc. -50.58 Million USD -81.349%
Spyre Therapeutics, Inc. -104.33 Million USD 12.084%
NKGen Biotech, Inc. Common Stock 19.64 Million USD 566.938%
Zura Bio Limited -99.8 Million USD 8.092%
PolyPid Ltd. 6.17 Million USD 1586.71%
Aileron Therapeutics, Inc. 74.12 Million USD 223.759%
NKGen Biotech, Inc. Warrants 19.64 Million USD 566.938%
Instil Bio, Inc. 75.35 Million USD 221.726%
argenx SE -2.02 Billion USD 95.479%
Immunome, Inc. -97.02 Million USD 5.461%
Compass Therapeutics, Inc. -22.49 Million USD -307.78%
Verona Pharma plc -220.44 Million USD 58.388%
enGene Holdings Inc. Warrants -71.74 Million USD -27.859%
Shattuck Labs, Inc. -121.42 Million USD 24.455%
CervoMed Inc. -7.79 Million USD -1077.105%
LENZ Therapeutics, Inc. -185.49 Million USD 50.55%
Plus Therapeutics, Inc. -4.37 Million USD -1997.645%
Dianthus Therapeutics, Inc. -131.73 Million USD 30.37%
Moolec Science SA 117.61 Thousand USD 78091.09%
Enveric Biosciences, Inc. -2.28 Million USD -3909.219%
Inovio Pharmaceuticals, Inc. 15.89 Million USD 676.977%
AnaptysBio, Inc. -18.15 Million USD -405.372%
Design Therapeutics, Inc. -18.15 Million USD -405.399%
Leap Therapeutics, Inc. -70.38 Million USD -30.333%
NeurAxis, Inc. 145.7 Thousand USD 63058.133%
Seelos Therapeutics, Inc. 11.23 Million USD 916.684%
Lumos Pharma, Inc. -28.49 Million USD -221.939%
Achilles Therapeutics plc -126.92 Million USD 27.728%
enGene Holdings Inc. Common Stock -71.74 Million USD -27.859%
180 Life Sciences Corp. -655.73 Thousand USD -13888.989%
Opiant Pharmaceuticals, Inc. -20.77 Million USD -341.565%
CERo Therapeutics Holdings, Inc. 1.45 Million USD 6390.947%
Nutriband Inc. -251.65 Thousand USD -36350.407%
ORIC Pharmaceuticals, Inc. -13.17 Million USD -596.454%
CG Oncology, Inc. Common stock -7.44 Million USD -1132.93%
Fractyl Health, Inc. Common Stock 340.19 Million USD 126.964%
Rani Therapeutics Holdings, Inc. 23.73 Million USD 486.476%
MoonLake Immunotherapeutics -447.47 Million USD 79.5%
Palisade Bio, Inc. -12.06 Million USD -660.424%
Tourmaline Bio, Inc. -140.31 Million USD 34.624%
Beam Therapeutics Inc. -262.72 Million USD 65.085%
Neurogene Inc. -131.95 Million USD 30.484%
Mirum Pharmaceuticals, Inc. 21.81 Million USD 520.471%
AEON Biopharma, Inc. -4.88 Million USD -1779.713%
CARGO Therapeutics, Inc. Common Stock -377.19 Million USD 75.681%
Sesen Bio, Inc. -112.55 Million USD 18.501%
Enliven Therapeutics, Inc. -99.86 Million USD 8.141%
Kiora Pharmaceuticals, Inc. -2.34 Million USD -3807.074%
Iovance Biotherapeutics, Inc. -39.02 Million USD -135.048%
Taysha Gene Therapies, Inc. -83.28 Million USD -10.144%
Athira Pharma, Inc. -88.99 Million USD -3.069%
Vaccinex, Inc. -1.28 Million USD -7021.894%
HCW Biologics Inc. 2.85 Million USD 3311.075%
XOMA Corporation -29 Million USD -216.31%
Nektar Therapeutics 210.24 Million USD 143.631%
Arvinas, Inc. -313.8 Million USD 70.768%
Tevogen Bio Holdings Inc. 1.62 Million USD 5752.262%
Merus N.V. -192.88 Million USD 52.443%
Omega Therapeutics, Inc. 59.98 Million USD 252.922%
Quince Therapeutics, Inc. -6.93 Million USD -1222.139%
Rezolute, Inc. -68.16 Million USD -34.565%
Clene Inc. 3.34 Million USD 2846.407%
Indaptus Therapeutics, Inc. -13.18 Million USD -595.609%
BeyondSpring Inc. -13.75 Million USD -566.885%
Synlogic, Inc. -6.68 Million USD -1272.177%
Allarity Therapeutics, Inc. 1.13 Million USD 8189.065%
Phio Pharmaceuticals Corp. -8.45 Million USD -984.92%
Peak Bio, Inc. 10.34 Million USD 987.124%
Werewolf Therapeutics, Inc. -82.42 Million USD -11.296%
Krystal Biotech, Inc. -350.23 Million USD 73.809%
Karyopharm Therapeutics Inc. 124.12 Million USD 173.901%
SpringWorks Therapeutics, Inc. -168.99 Million USD 45.721%
Lipella Pharmaceuticals Inc. -3.15 Million USD -2805.474%
MannKind Corporation 143.89 Million USD 163.746%
Ikena Oncology, Inc. -109.15 Million USD 15.964%
Cyclerion Therapeutics, Inc. -7.57 Million USD -1111.597%
Gyre Therapeutics, Inc. -33.1 Million USD -177.13%
Gossamer Bio, Inc. 180.35 Million USD 150.861%
CohBar, Inc. -5.93 Million USD -1446.69%
Cognition Therapeutics, Inc. -29.74 Million USD -208.357%
NRx Pharmaceuticals, Inc. 4.56 Million USD 2108.979%
Legend Biotech Corporation -949.39 Million USD 90.338%
Mural Oncology plc -255.84 Million USD 64.146%
Biora Therapeutics, Inc. 32.21 Million USD 384.743%
PaxMedica, Inc. Common Stock -4.71 Million USD -1847.293%
Disc Medicine, Inc. -358.28 Million USD 74.397%
Champions Oncology, Inc. 4.81 Million USD 2006.276%
REGENXBIO Inc. 54.76 Million USD 267.488%
Ensysce Biosciences, Inc. -268.9 Thousand USD -34012.165%
Anavex Life Sciences Corp. -151.02 Million USD 39.261%
Cellectar Biosciences, Inc. -9.01 Million USD -917.864%
Edgewise Therapeutics, Inc. -80.68 Million USD -13.692%
Vaxart, Inc. -8.24 Million USD -1013.093%
PharmaCyte Biotech, Inc. -50.17 Million USD -82.802%
Aldeyra Therapeutics, Inc. -127.16 Million USD 27.866%
Cellectis S.A. -43.85 Million USD -109.167%
Longeveron Inc. -2.9 Million USD -3054.402%
Repare Therapeutics Inc. -107.85 Million USD 14.953%
Sarepta Therapeutics, Inc. 968.37 Million USD 109.473%
Inozyme Pharma, Inc. 12 Million USD 864.162%
Revolution Medicines, Inc. -608.2 Million USD 84.918%
Nymox Pharmaceutical Corporation -1.23 Million USD -7357.724%
Third Harmonic Bio, Inc. -265.11 Million USD 65.4%
ArriVent BioPharma, Inc. Common Stock -150.07 Million USD 38.876%
AN2 Therapeutics, Inc. -15.64 Million USD -486.247%
Anixa Biosciences, Inc. -740 Thousand USD -12295.946%
Vertex Pharmaceuticals Incorporated -9.56 Billion USD 99.041%
Denali Therapeutics Inc. -74.86 Million USD -22.527%
Revelation Biosciences, Inc. -11.99 Million USD -664.946%
Veru Inc. 4.77 Million USD 2019.05%
Corvus Pharmaceuticals, Inc. -11.24 Million USD -715.668%
Cingulate Inc. 3.08 Million USD 3075.655%
Passage Bio, Inc. 4.58 Million USD 2100.654%
Context Therapeutics Inc. -14.44 Million USD -534.817%
Exicure, Inc. 5.84 Million USD 1668.302%
Day One Biopharmaceuticals, Inc. -230.37 Million USD 60.182%
Oramed Pharmaceuticals Inc. -39.57 Million USD -131.817%
Scinai Immunotherapeutics Ltd. 15.69 Million USD 684.603%
Rhythm Pharmaceuticals, Inc. -58.82 Million USD -55.948%
Nuvalent, Inc. -335.38 Million USD 72.65%
ABVC BioPharma, Inc. 1.73 Million USD 5389.041%
Carisma Therapeutics, Inc. -74.48 Million USD -23.157%
Unicycive Therapeutics, Inc. -8.89 Million USD -931.834%
OmniAb, Inc. 9.2 Million USD 1096.74%
Anew Medical, Inc. 1.43 Million USD 6503.647%
Fennec Pharmaceuticals Inc. 16.38 Million USD 659.952%
Lipocine Inc. -4.75 Million USD -1829.293%
Lexeo Therapeutics, Inc. Common Stock -109.82 Million USD 16.478%
Nautilus Biotechnology, Inc. 15.23 Million USD 702.259%
SAB Biotherapeutics, Inc. -50.65 Million USD -81.073%
G1 Therapeutics, Inc. 24.89 Million USD 468.512%
Bellerophon Therapeutics, Inc. -6.72 Million USD -1264.827%
Sage Therapeutics, Inc. -65.82 Million USD -39.35%
Ocugen, Inc. -32.52 Million USD -182.064%
Mind Medicine (MindMed) Inc. -85.57 Million USD -7.193%
Q32 Bio Inc. -37.94 Million USD -141.726%
Brainstorm Cell Therapeutics Inc. -628 Thousand USD -14506.688%
Alumis Inc. Common Stock -13.52 Million USD -578.025%
Equillium, Inc. -22.39 Million USD -309.655%
Kyverna Therapeutics, Inc. -25.56 Million USD -258.769%
Coya Therapeutics, Inc. -32.62 Million USD -181.15%
CNS Pharmaceuticals, Inc. -247.91 Thousand USD -36900.585%
Galera Therapeutics, Inc. 134.04 Million USD 168.434%
Evelo Biosciences, Inc. 3.19 Million USD 2968.355%
Comera Life Sciences Holdings, Inc. 328.44 Thousand USD 28028.913%
Dominari Holdings Inc. 195 Thousand USD 47141.026%
Edesa Biotech, Inc. -5.26 Million USD -1641.628%
vTv Therapeutics Inc. -8.91 Million USD -928.709%
Bio-Techne Corporation 267.74 Million USD 134.26%
Agios Pharmaceuticals, Inc. -16.2 Million USD -465.92%
Harmony Biosciences Holdings, Inc. -118.09 Million USD 22.325%
Prelude Therapeutics Incorporated -8.4 Million USD -991.634%
Candel Therapeutics, Inc. -12.65 Million USD -625.081%
iTeos Therapeutics, Inc. -245.11 Million USD 62.577%
Nkarta, Inc. 57.29 Million USD 260.09%
BioCardia, Inc. 212 Thousand USD 43368.868%
Iterum Therapeutics plc 13.43 Million USD 782.616%